{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,19]],"date-time":"2026-05-19T05:17:54Z","timestamp":1779167874466,"version":"3.51.4"},"reference-count":22,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2022,4,26]],"date-time":"2022-04-26T00:00:00Z","timestamp":1650931200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,2,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>There is lack of knowledge concerning postpartum infections in women with inflammatory bowel disease (IBD). Our aim is to determine the 30-day postpartum infectious complications in women with and without IBD who have a caesarian section, normal vaginal delivery, or assisted vaginal delivery.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We used Danish national registries to establish a study population of liveborn, singleton births from January 1, 1997, through December 31, 2015. We examined 30-day postpartum maternal infectious complications in women with and without IBD, according to the mode of delivery. Statistical models were adjusted for multiple confounders.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In all, 3255 women with and 207 608 without IBD had a caesarian section. Within 30 days postpartum, 4.5% of women with and 3.7% without IBD had an infectious complication. Increased infectious complications included overall infections (adjusted OR [aOR], 1.83; 95% confidence interval [CI], 1.35\u20132.47), infections of the gastrointestinal tract (aOR, 4.36, 95% CI 2.34-8.10), and infections of the skin and subcutaneous tissue (aOR, 4.45; 95% CI, 2.30\u20138.50). Other puerperal infections, urological and gynecological, and other infections were increased, although not significantly. For vaginal deliveries, 1.6% of 5771 women with IBD and 1.3% of 793 110 women without IBD had an infectious complication, and the aOR of infections of the gastrointestinal tract was 3.17 (95% CI, 1.47\u20136.85). There were too few outcomes to calculate the risk of infections after assisted vaginal delivery.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The risk of a 30-day postpartum infectious complication is increased in women with IBD. Physicians should carefully monitor their patients postpartum to prevent these adverse outcomes.<\/jats:p><\/jats:sec>","DOI":"10.1093\/ibd\/izac088","type":"journal-article","created":{"date-parts":[[2022,4,26]],"date-time":"2022-04-26T19:24:20Z","timestamp":1651001060000},"page":"260-267","source":"Crossref","is-referenced-by-count":10,"title":["Increased Risk of Postpartum Infections After Caesarian and Vaginal Delivery in Women With Inflammatory Bowel Disease: A Danish Nationwide Cohort Study"],"prefix":"10.1093","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2720-4404","authenticated-orcid":false,"given":"Sonia","family":"Friedman","sequence":"first","affiliation":[{"name":"Division of Gastroenterology, Hepatology, and Endoscopy, Department of Medicine, Brigham and Women\u2019s Hospital, Boston, Massachusetts and Harvard Medical School , Boston, MA , USA"},{"name":"Center for Clinical Epidemiology, Odense University Hospital, Odense , Denmark"},{"name":"Research 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Epidemiology, Odense University Hospital, Odense , Denmark"},{"name":"Research Unit of Clinical Epidemiology, Department of Clinical Research, University of Southern Denmark , Odense , Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bente Mertz","family":"N\u00f8rg\u00e5rd","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Hepatology, and Endoscopy, Department of Medicine, Brigham and Women\u2019s Hospital, Boston, Massachusetts and Harvard Medical School , Boston, MA , USA"},{"name":"Center for Clinical Epidemiology, Odense University Hospital, Odense , Denmark"},{"name":"Research Unit of Clinical Epidemiology, Department of Clinical Research, University of Southern Denmark , Odense , 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