{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,14]],"date-time":"2026-03-14T03:12:55Z","timestamp":1773457975582,"version":"3.50.1"},"reference-count":40,"publisher":"Oxford University Press (OUP)","license":[{"start":{"date-parts":[[2019,5,15]],"date-time":"2019-05-15T00:00:00Z","timestamp":1557878400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"name":"Catalan Society of Gastroenterology"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Fatigue is a common symptom in patients with inflammatory bowel disease (IBD), and it often persists despite clinical remission. Acupuncture has been shown to be effective for treating fatigue in patients with many chronic diseases. The main objective of the study was to assess the efficacy of electroacupuncture (EAc), compared with sham EAc (ShEAc) or being on a waitlist (WL), for treating fatigue in patients with quiescent IBD in a single-blind randomized trial.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>Fifty-two patients with IBD in clinical remission and fatigue were randomly assigned to 1 of 3 groups: EAc, ShEAc, or WL. Patients in the EAc and ShEAc groups received 9 sessions over 8 weeks. Fatigue was evaluated with the IBD-validated Functional Assessment of Chronic Illness Therapy-Fatigue Scale (FACIT-FS).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Baseline characteristics were similar in the 3 groups. Both EAc and ShEAc presented improved Functional Assessment of Chronic Illness Therapy-Fatigue Scale scores compared with baseline: the respective improvements were 9.53 (95% confidence intervals, 6.75\u201312.3, P &lt; 0.001) and 5.46 points (95% confidence intervals, 2.7\u20139.7, P = 0.015), respectively. No significant changes were observed in the WL group. In the comparison of treatment groups, EAc was nonsignificantly better than ShEAc (EAc, 33.27 and ShEAc, 28.13, P = 0.168); both EAc and ShEAc improved fatigue scores significantly compared to WL (24.5; P = 0.01 and 0.04, respectively).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>Both EAc and ShEAc reduced fatigue scores in IBD patients when compared to WL. No differences were observed between EAc and ShEAc, although the study was not powered to rule out a difference. Acupuncture may offer improvements to patients with few other treatment alternatives. Clinical Trials Org Id: NCT02733276.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ibd\/izz091","type":"journal-article","created":{"date-parts":[[2019,5,15]],"date-time":"2019-05-15T16:33:05Z","timestamp":1557937985000},"source":"Crossref","is-referenced-by-count":16,"title":["A Prospective Pilot Randomized Study: Electroacupuncture vs. Sham Procedure for the Treatment of Fatigue in Patients With Quiescent Inflammatory Bowel Disease"],"prefix":"10.1093","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3675-1135","authenticated-orcid":false,"given":"Diana","family":"Horta","sequence":"first","affiliation":[{"name":"Digestive Diseases Unit, Hospital Universitari Parc Taul\u00ed, Sabadell, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alba","family":"Lira","sequence":"additional","affiliation":[{"name":"Digestive Diseases Unit, Hospital Universitari Parc Taul\u00ed, Sabadell, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Meritxell","family":"Sanchez-Lloansi","sequence":"additional","affiliation":[{"name":"Digestive Diseases Unit, Hospital Universitari Parc Taul\u00ed, Sabadell, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Albert","family":"Villoria","sequence":"additional","affiliation":[{"name":"Digestive Diseases Unit, Hospital Universitari Parc Taul\u00ed, Sabadell, Spain"},{"name":"Department of Medicine, Universitat Autonoma de Barcelona, Bellaterra, Spain"},{"name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Hep\u00e1ticas y Digestivas (CIBERehd), Instituto de Salud Carlos III, Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcelo","family":"Teggiachi","sequence":"additional","affiliation":[{"name":"Private medical acupuncturist, Sabadell, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dario","family":"Garc\u00eda-Rojo","sequence":"additional","affiliation":[{"name":"Medical Acupuncturist. Hospital Universitari Parc Taul\u00ed, Sabadell, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Susana","family":"Garc\u00eda-Molina","sequence":"additional","affiliation":[{"name":"Private medical acupuncturist, Sabadell, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ariadna","family":"Figuerola","sequence":"additional","affiliation":[{"name":"Digestive Diseases Unit, Hospital Universitari Parc Taul\u00ed, Sabadell, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria","family":"Esteve","sequence":"additional","affiliation":[{"name":"Digestive Diseases Unit, Hospital Universitari Mutua Terrassa, Terrassa, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xavier","family":"Calvet","sequence":"additional","affiliation":[{"name":"Digestive Diseases Unit, Hospital Universitari Parc Taul\u00ed, Sabadell, Spain"},{"name":"Department of Medicine, Universitat Autonoma de Barcelona, Bellaterra, Spain"},{"name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Hep\u00e1ticas y Digestivas (CIBERehd), Instituto de Salud Carlos III, Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2019,5,15]]},"reference":[{"key":"2019071109554971000_CIT0001","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1111\/j.1365-2036.2011.04914.x","article-title":"Fatigue in out-patients with inflammatory bowel disease is common and multifactorial","volume":"35","author":"Bager","year":"2012","journal-title":"Aliment Pharmacol Ther."},{"key":"2019071109554971000_CIT0002","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1093\/ecco-jcc\/jjv168","article-title":"Practical guideline for fatigue management in inflammatory bowel disease","volume":"10","author":"Kreijne","year":"2016","journal-title":"J Crohns 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