{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T07:48:42Z","timestamp":1781596122532,"version":"3.54.5"},"reference-count":14,"publisher":"Oxford University Press (OUP)","issue":"9","license":[{"start":{"date-parts":[[2019,10,21]],"date-time":"2019-10-21T00:00:00Z","timestamp":1571616000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,8,20]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Introduction<\/jats:title>\n                  <jats:p>Due to concerns over wound healing, hemorrhoidectomy in patients with Crohn\u2019s disease (CD) remains controversial. We sought to ascertain safety and efficacy of excisional hemorrhoidectomy in CD.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>A retrospective review of all adult CD patients undergoing excisional hemorrhoidectomy between January 1, 1995, and January 1, 2019, at 2 IBD referral centers was performed. Data collected included patient demographics, clinical characteristics of CD (anorectal symptoms; prior nonoperative hemorrhoidal therapy; presence of other perianal disease; and activity, duration, and anatomic location of CD), and postoperative complications including bleeding, wound healing, and need for further therapy or surgical intervention after surgery.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>A total of 36 adult patients with Crohn\u2019s disease with symptomatic hemorrhoidal disease were included. The study cohort included 16 males (44%), and median age was 49 (range, 21 to 77) years. Predominant symptoms included pain (n = 16; 44%), prolapse (n = 8; 22%), and bleeding (n = 12; 33%). Sixteen patients (44%) had nonoperative therapy before surgery. Twenty-four patients (67%) had other perianal disease. At the time of hemorrhoidectomy, 9 patients (25%) were exposed to corticosteroids, 8 patients (25%) to immunomodulators, and 9 patients (25%) to biologics. During a median follow-up time of 31.5 (range, 1 to 255) months after hemorrhoidectomy, 4 patients (11%) had complications (1 developed a stricture, 1 developed a perianal abscess\/fistula, 1 had a nonhealing wound, and 1 had hemorrhoidal recurrence).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>Our data suggest that excisional hemorrhoidectomy may be performed safely in CD patients who have failed nonoperative hemorrhoidal therapy without concern for de novo perianal disease or need for proctectomy.<\/jats:p>\n                  <jats:p>Hemorrhoidal disease is common in patients with Crohn\u2019s disease. This study sought to understand the outcomes of surgically treating hemorrhoids in patients with Crohn\u2019s disease.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ibd\/izz255","type":"journal-article","created":{"date-parts":[[2019,10,21]],"date-time":"2019-10-21T09:43:39Z","timestamp":1571651019000},"page":"1390-1393","source":"Crossref","is-referenced-by-count":13,"title":["Excisional Hemorrhoidectomy: Safe in Patients With Crohn\u2019s Disease?"],"prefix":"10.1093","volume":"26","author":[{"given":"Amy L","family":"Lightner","sequence":"first","affiliation":[{"name":"Department of Colorectal Surgery, Digestive Disease Surgical Institute, Cleveland Clinic, Cleveland, OH"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Kearney","sequence":"additional","affiliation":[{"name":"Department of Colorectal Surgery, Digestive Disease Surgical Institute, Cleveland Clinic, Cleveland, OH"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danica","family":"Giugliano","sequence":"additional","affiliation":[{"name":"Department of Colorectal Surgery, Digestive Disease Surgical Institute, Cleveland Clinic, Cleveland, OH"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tracy","family":"Hull","sequence":"additional","affiliation":[{"name":"Department of Colorectal Surgery, Digestive Disease Surgical Institute, Cleveland Clinic, Cleveland, OH"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefan D","family":"Holubar","sequence":"additional","affiliation":[{"name":"Department of Colorectal Surgery, Digestive Disease Surgical Institute, Cleveland Clinic, Cleveland, OH"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sharon","family":"Koh","sequence":"additional","affiliation":[{"name":"Division of Colon and Rectal Surgery, Cedars-Sinai Medical Center, Los Angeles, CA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karen","family":"Zaghiyan","sequence":"additional","affiliation":[{"name":"Division of Colon and Rectal Surgery, Cedars-Sinai Medical Center, Los Angeles, CA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Phillip R","family":"Fleshner","sequence":"additional","affiliation":[{"name":"Division of Colon and Rectal Surgery, Cedars-Sinai Medical Center, Los Angeles, CA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2019,10,21]]},"reference":[{"key":"2020082023070069800_CIT0001","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1097\/DCR.0b013e31825228b0","article-title":"The spectrum of perianal Crohn\u2019s disease in a population-based cohort","volume":"55","author":"Eglinton","year":"2012","journal-title":"Dis Colon Rectum."},{"key":"2020082023070069800_CIT0002","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1111\/codi.12555","article-title":"Is haemorrhoidectomy in inflammatory bowel disease harmful? 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