{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T05:36:51Z","timestamp":1791178611732,"version":"4.1.0"},"reference-count":60,"publisher":"Oxford University Press (OUP)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Integrative and Comparative Biology"],"DOI":"10.1093\/icb\/icn046","type":"journal-article","created":{"date-parts":[[2008,6,22]],"date-time":"2008-06-22T00:25:23Z","timestamp":1214094323000},"page":"494-504","source":"Crossref","is-referenced-by-count":46,"title":["Three tiers of genome evolution in reptiles"],"prefix":"10.1093","volume":"48","author":[{"given":"C. L.","family":"Organ","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R. G.","family":"Moreno","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S. V.","family":"Edwards","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2008,6,2]]},"reference":[{"key":"1_31843824","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1534\/genetics.106.058917","volume":"174","year":"2006","ISSN":"https:\/\/id.crossref.org\/issn\/0016-6731","issn-type":"print"},{"issue":"1","key":"2_22814179","doi-asserted-by":"publisher","first-page":"26","DOI":"10.1093\/molbev\/msl150","volume":"24","year":"2007","journal-title":"Molecular Biology and Evolution","ISSN":"https:\/\/id.crossref.org\/issn\/0737-4038","issn-type":"print"},{"issue":"1","key":"3_6411507","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1016\/S0378-1119(99)00485-0","volume":"241","author":"Bernardi","year":"2000","journal-title":"Gene","ISSN":"https:\/\/id.crossref.org\/issn\/0378-1119","issn-type":"print"},{"issue":"5","key":"4_18166435","doi-asserted-by":"publisher","first-page":"925","DOI":"10.1101\/gr.1860604","volume":"14","year":"2004","journal-title":"Genome Research","ISSN":"https:\/\/id.crossref.org\/issn\/1088-9051","issn-type":"print"},{"issue":"3","key":"5_28568990","doi-asserted-by":"publisher","first-page":"257","DOI":"10.1098\/rsbl.2006.0611","volume":"3","author":"Brown","year":"2007","journal-title":"Biology Letters","ISSN":"https:\/\/id.crossref.org\/issn\/1744-9561","issn-type":"print"},{"issue":"1","key":"6_16778796","doi-asserted-by":"publisher","first-page":"78","DOI":"10.1006\/jmbi.1997.0951","volume":"268","author":"Burge","year":"1997","journal-title":"Journal of molecular biology","ISSN":"https:\/\/id.crossref.org\/issn\/0022-2836","issn-type":"print"},{"issue":"1-4","key":"7_17335924","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1159\/000063018","volume":"96","author":"Burt","year":"2002","journal-title":"Cytogenetic and genome research","ISSN":"https:\/\/id.crossref.org\/issn\/1424-8581","issn-type":"print"},{"issue":"1","key":"8_4770244","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1242\/jcs.34.1.247","volume":"34","author":"Cavalier-Smith","year":"1978","journal-title":"Journal of Cell Science","ISSN":"https:\/\/id.crossref.org\/issn\/0021-9533","issn-type":"print"},{"key":"9_31341257","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1007\/BF00058691","volume":"71","year":"1986","journal-title":"Genetica","ISSN":"https:\/\/id.crossref.org\/issn\/0016-6707","issn-type":"print"},{"key":"10_31341258","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1007\/BF00123167","volume":"72","year":"1987","journal-title":"Genetica","ISSN":"https:\/\/id.crossref.org\/issn\/0016-6707","issn-type":"print"},{"issue":"3","key":"11_15846192","doi-asserted-by":"publisher","first-page":"308","DOI":"10.1007\/BF00163235","volume":"40","author":"Duret","year":"1995","journal-title":"Journal of Molecular Evolution","ISSN":"https:\/\/id.crossref.org\/issn\/0022-2844","issn-type":"print"},{"issue":"1-4","key":"12_29194476","doi-asserted-by":"publisher","first-page":"120","DOI":"10.1159\/000103172","volume":"117","author":"Ellegren","year":"2007","journal-title":"Cytogenetic and genome research","ISSN":"https:\/\/id.crossref.org\/issn\/1424-8581","issn-type":"print"},{"issue":"4","key":"13_23089772","doi-asserted-by":"publisher","first-page":"543","DOI":"10.1098\/rsbl.2006.0523","volume":"2","author":"Ericson","year":"2006","journal-title":"Biology Letters","ISSN":"https:\/\/id.crossref.org\/issn\/1744-9561","issn-type":"print"},{"issue":"1","key":"14_18416091","doi-asserted-by":"publisher","first-page":"197","DOI":"10.1016\/j.ympev.2004.04.018","volume":"33","author":"Evans","year":"2004","journal-title":"Molecular phylogenetics and evolution","ISSN":"https:\/\/id.crossref.org\/issn\/1055-7903","issn-type":"print"},{"key":"16_31117315","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1016\/j.zool.2007.02.003","volume":"110","year":"2007","journal-title":"ZOOLOGY"},{"issue":"3","key":"17_18165245","doi-asserted-by":"publisher","first-page":"1031","DOI":"10.1016\/j.ympev.2003.09.016","volume":"31","author":"Fujita","year":"2004","journal-title":"Molecular phylogenetics and evolution","ISSN":"https:\/\/id.crossref.org\/issn\/1055-7903","issn-type":"print"},{"issue":"10","key":"18_19449893","doi-asserted-by":"publisher","first-page":"1451","DOI":"10.1101\/gr.4086505","volume":"15","year":"2005","journal-title":"Genome Research","ISSN":"https:\/\/id.crossref.org\/issn\/1088-9051","issn-type":"print"},{"issue":"11","key":"20_29754257","doi-asserted-by":"publisher","first-page":"1547","DOI":"10.1101\/gr.7050807","volume":"17","author":"Green","year":"2007","journal-title":"Genome Research","ISSN":"https:\/\/id.crossref.org\/issn\/1088-9051","issn-type":"print"},{"issue":"1","key":"21_11128053","first-page":"65","volume":"76","author":"Gregory","year":"2001","journal-title":"Biological Reviews (Cambridge; Print)","ISSN":"https:\/\/id.crossref.org\/issn\/0006-3231","issn-type":"print"},{"key":"25_31566905","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1038\/nature03154","volume":"432","year":"2004","ISSN":"https:\/\/id.crossref.org\/issn\/1476-4687","issn-type":"print"},{"issue":"database_issue","key":"26_23449653","doi-asserted-by":"publisher","first-page":"D610","DOI":"10.1093\/nar\/gkl996","volume":"35","year":"2007","journal-title":"Nucleic Acids Research","ISSN":"https:\/\/id.crossref.org\/issn\/0305-1048","issn-type":"print"},{"issue":"11","key":"27_6361511","doi-asserted-by":"crossref","first-page":"1521","DOI":"10.1093\/oxfordjournals.molbev.a026064","volume":"16","author":"Hughes","year":"1999","journal-title":"Molecular Biology and Evolution","ISSN":"https:\/\/id.crossref.org\/issn\/0737-4038","issn-type":"print"},{"key":"28_31541612","doi-asserted-by":"crossref","first-page":"860","DOI":"10.1038\/35057062","volume":"409","year":"2001","ISSN":"https:\/\/id.crossref.org\/issn\/1476-4687","issn-type":"print"},{"issue":"1-2","key":"29_5881215","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1016\/S0378-1119(97)00475-7","volume":"205","author":"Jabbari","year":"1997","journal-title":"Gene","ISSN":"https:\/\/id.crossref.org\/issn\/0378-1119","issn-type":"print"},{"issue":"1","key":"30_17466483","doi-asserted-by":"publisher","first-page":"51","DOI":"10.1093\/nar\/gkg129","volume":"31","author":"Karolchik","year":"2003","journal-title":"Nucleic Acids Research","ISSN":"https:\/\/id.crossref.org\/issn\/0305-1048","issn-type":"print"},{"issue":"6","key":"31_17083005","doi-asserted-by":"publisher","first-page":"996","DOI":"10.1101\/gr.229102. Article published online before print in May 2002","volume":"12","year":"2002","journal-title":"Genome Research","ISSN":"https:\/\/id.crossref.org\/issn\/1088-9051","issn-type":"print"},{"issue":"1-2","key":"32_23479908","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1016\/j.gene.2006.09.026","volume":"388","author":"Kumazawa","year":"2007","journal-title":"Gene","ISSN":"https:\/\/id.crossref.org\/issn\/0378-1119","issn-type":"print"},{"key":"33_31541612","doi-asserted-by":"crossref","first-page":"860","DOI":"10.1038\/35057062","volume":"409","year":"2001","ISSN":"https:\/\/id.crossref.org\/issn\/1476-4687","issn-type":"print"},{"issue":"2","key":"34_19468529","doi-asserted-by":"publisher","first-page":"581","DOI":"10.1016\/j.ympev.2005.07.016","volume":"37","author":"Lawson","year":"2005","journal-title":"Molecular phylogenetics and evolution","ISSN":"https:\/\/id.crossref.org\/issn\/1055-7903","issn-type":"print"},{"key":"35_31117317","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1017\/S1477200007002290","volume":"5","year":"2007","journal-title":"SYSTEM BIODIVERS"},{"issue":"2","key":"36_21089284","doi-asserted-by":"publisher","first-page":"450","DOI":"10.1093\/molbev\/msj050","volume":"23","year":"2006","journal-title":"Molecular Biology and Evolution","ISSN":"https:\/\/id.crossref.org\/issn\/0737-4038","issn-type":"print"},{"issue":"6","key":"39_18363970","doi-asserted-by":"publisher","first-page":"984","DOI":"10.1093\/molbev\/msh070","volume":"21","year":"2004","journal-title":"Molecular Biology and Evolution","ISSN":"https:\/\/id.crossref.org\/issn\/0737-4038","issn-type":"print"},{"issue":"9","key":"40_29104520","doi-asserted-by":"publisher","first-page":"1254","DOI":"10.1101\/gr.6316407","volume":"17","year":"2007","journal-title":"Genome Research","ISSN":"https:\/\/id.crossref.org\/issn\/1088-9051","issn-type":"print"},{"issue":"2","key":"41_18696885","doi-asserted-by":"publisher","first-page":"137","DOI":"10.1086\/427734","volume":"165","author":"Near","year":"2005","ISSN":"https:\/\/id.crossref.org\/issn\/1537-5323","issn-type":"print"},{"issue":"2-3","key":"42_19498257","doi-asserted-by":"publisher","first-page":"185","DOI":"10.1007\/s10709-005-8008-2","volume":"125","author":"Olmo","year":"2005","journal-title":"Genetica","ISSN":"https:\/\/id.crossref.org\/issn\/0016-6707","issn-type":"print"},{"issue":"2","key":"43_17260948","doi-asserted-by":"publisher","first-page":"317","DOI":"10.1016\/S0378-1119(02)00685-6","volume":"295","author":"Olmo","year":"2002","journal-title":"Gene","ISSN":"https:\/\/id.crossref.org\/issn\/0378-1119","issn-type":"print"},{"key":"44_31566928","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1038\/nature05621","volume":"446","year":"2007","ISSN":"https:\/\/id.crossref.org\/issn\/1476-4687","issn-type":"print"},{"key":"45_28354037","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1111\/j.1463-6409.1997.tb00423.x","volume":"26","year":"1997","journal-title":"Zoologica Scripta","ISSN":"https:\/\/id.crossref.org\/issn\/0300-3256","issn-type":"print"},{"key":"46_31548080","doi-asserted-by":"crossref","first-page":"877","DOI":"10.1038\/44766","volume":"401","year":"1999","ISSN":"https:\/\/id.crossref.org\/issn\/1476-4687","issn-type":"print"},{"issue":"7","key":"47_6401323","doi-asserted-by":"publisher","first-page":"541","DOI":"10.1023\/A:1009241528994","volume":"7","author":"Pigozzi","year":"1999","journal-title":"Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology","ISSN":"https:\/\/id.crossref.org\/issn\/0967-3849","issn-type":"print"},{"issue":"2","key":"48_17817573","doi-asserted-by":"publisher","first-page":"289","DOI":"10.1016\/S1055-7903(03)00108-8","volume":"29","author":"Rest","year":"2003","journal-title":"Molecular phylogenetics and evolution","ISSN":"https:\/\/id.crossref.org\/issn\/1055-7903","issn-type":"print"},{"key":"49_31341259","first-page":"97","volume":"32","year":"1996","journal-title":"RUSS J GENET"},{"key":"50_31341260","first-page":"151","volume":"28","year":"1992","journal-title":"RUSS J GENET"},{"key":"51_31341261","first-page":"53","volume":"28","year":"1992","journal-title":"RUSS J GENET"},{"issue":"6","key":"53_23756461","doi-asserted-by":"publisher","first-page":"902","DOI":"10.1080\/10635150601091924","volume":"55","author":"Shedlock","year":"2006","journal-title":"Systematic Biology","ISSN":"https:\/\/id.crossref.org\/issn\/1063-5157","issn-type":"print"},{"issue":"8","key":"54_23646703","doi-asserted-by":"publisher","first-page":"2767","DOI":"10.1073\/pnas.0606204104","volume":"104","year":"2007","journal-title":"PNAS","ISSN":"https:\/\/id.crossref.org\/issn\/0027-8424","issn-type":"print"},{"issue":"1","key":"55_18378881","doi-asserted-by":"publisher","first-page":"111","DOI":"10.1159\/000078570","volume":"106","author":"Shibusawa","year":"2004","journal-title":"Cytogenetic and genome research","ISSN":"https:\/\/id.crossref.org\/issn\/1424-8581","issn-type":"print"},{"issue":"2","key":"56_6567582","doi-asserted-by":"publisher","first-page":"96","DOI":"10.1046\/j.1365-2052.2000.00565.x","volume":"31","author":"Smith","year":"2000","journal-title":"Animal genetics","ISSN":"https:\/\/id.crossref.org\/issn\/0268-9146","issn-type":"print"},{"issue":"8","key":"57_22144279","doi-asserted-by":"publisher","first-page":"430","DOI":"10.1016\/j.tree.2004.05.006","volume":"19","author":"Springer","year":"2004","journal-title":"Trends in Ecology & Evolution","ISSN":"https:\/\/id.crossref.org\/issn\/0169-5347","issn-type":"print"},{"issue":"6","key":"58_6020713","doi-asserted-by":"crossref","first-page":"993","DOI":"10.1093\/oxfordjournals.jbchem.a022066","volume":"123","author":"Tajima","year":"1998","journal-title":"Journal of Biochemistry","ISSN":"https:\/\/id.crossref.org\/issn\/0021-924X","issn-type":"print"},{"issue":"1","key":"59_12708756","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1007\/BF00332341","volume":"46","author":"Takagi","year":"1974","journal-title":"Chromosoma","ISSN":"https:\/\/id.crossref.org\/issn\/0009-5915","issn-type":"print"},{"key":"60_23082571","doi-asserted-by":"publisher","first-page":"122","DOI":"10.1016\/j.gene.2006.05.034","volume":"385","author":"Varriale","year":"2006","journal-title":"Gene","ISSN":"https:\/\/id.crossref.org\/issn\/0378-1119","issn-type":"print"},{"issue":"5507","key":"61_11044188","doi-asserted-by":"publisher","first-page":"1304","DOI":"10.1126\/science.1058040","volume":"291","author":"Venter","year":"2001","journal-title":"Science","ISSN":"https:\/\/id.crossref.org\/issn\/0036-8075","issn-type":"print"},{"issue":"2","key":"62_23661134","doi-asserted-by":"publisher","first-page":"182","DOI":"10.1016\/j.crvi.2006.10.001","volume":"330","author":"Vidal","year":"2007","journal-title":"Comptes rendus biologies","ISSN":"https:\/\/id.crossref.org\/issn\/1631-0691","issn-type":"print"},{"issue":"10-11","key":"63_19600272","doi-asserted-by":"crossref","first-page":"1000","DOI":"10.1016\/j.crvi.2005.10.001","volume":"328","author":"Vidal","year":"2005","journal-title":"Comptes rendus biologies","ISSN":"https:\/\/id.crossref.org\/issn\/1631-0691","issn-type":"print"},{"key":"64_25203567","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1086\/342079","volume":"160","year":"2002","ISSN":"https:\/\/id.crossref.org\/issn\/1537-5323","issn-type":"print"},{"key":"65_31579109","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1038\/nature06936","volume":"453","year":"2008","ISSN":"https:\/\/id.crossref.org\/issn\/1476-4687","issn-type":"print"},{"issue":"6","key":"66_21808831","doi-asserted-by":"publisher","first-page":"1203","DOI":"10.1093\/molbev\/msk008","volume":"23","year":"2006","journal-title":"Molecular Biology and Evolution","ISSN":"https:\/\/id.crossref.org\/issn\/0737-4038","issn-type":"print"},{"issue":"1","key":"67_21854167","first-page":"123","volume":"60","author":"Wiens","year":"2006","journal-title":"Evolution","ISSN":"https:\/\/id.crossref.org\/issn\/0014-3820","issn-type":"print"},{"issue":"1","key":"68_23124210","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1086\/510560","volume":"80","author":"Wong","year":"2007","journal-title":"American journal of human genetics","ISSN":"https:\/\/id.crossref.org\/issn\/0002-9297","issn-type":"print"}],"container-title":["Integrative and Comparative Biology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/icb\/article-pdf\/48\/4\/494\/1670977\/icn046.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,9,12]],"date-time":"2021-09-12T13:53:41Z","timestamp":1631454821000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/icb\/article-lookup\/doi\/10.1093\/icb\/icn046"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,6,2]]},"references-count":60,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2008,6,2]]}},"URL":"https:\/\/doi.org\/10.1093\/icb\/icn046","relation":{},"ISSN":["1540-7063","1557-7023"],"issn-type":[{"value":"1540-7063","type":"print"},{"value":"1557-7023","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,6,2]]}}}