{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,4]],"date-time":"2026-04-04T18:02:00Z","timestamp":1775325720779,"version":"3.50.1"},"reference-count":7,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2020,2,22]],"date-time":"2020-02-22T00:00:00Z","timestamp":1582329600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,5,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Impella\u00ae pumps are increasingly utilized in patients in cardiogenic shock. We report on a case series where Impella support was insufficient, and a switch to venoarterial extracorporeal membrane oxygenation (VA ECMO) became necessary. ECMO patients with previous Impella devices were identified utilizing our institutional ECMO database. Since 2014, 10 patients with a mean age of 62\u2009\u00b1\u20093\u2009years were identified. Despite correct placement of all Impella pumps, cardiogenic shock persisted with progressive multi-organ failure (Impella type 2.5\/CP n\u2009=\u20096\/4 patients). Femoro-femoral VA ECMO was implanted percutaneously on the contralateral side with the Impella initially left on standby but retracted into the descending aorta for transport reasons after a mean support time of 20\u2009\u00b1\u20098\u2009h. All patients were able to unload their heart by left ventricular ejection with a blood pressure amplitude of 15\u2009\u00b1\u20093\u2009mmHg on VA ECMO support. After VA ECMO implantation haemodynamic parameters improved significantly within 24\u2009h of support (mean serum lactate levels decreased from 92\u2009\u00b1\u200917 to 44\u2009\u00b1\u200910\u2009mg\/dl, P\u2009=\u20090.031). Survival to hospital discharge was 70%. These data indicate that the Impella 2.5\u00ae and CP\u00ae might not be sufficient in profound cardiogenic shock. Comparative studies are necessary to specify which patient population benefits from which type of circulatory support.<\/jats:p>","DOI":"10.1093\/icvts\/ivaa015","type":"journal-article","created":{"date-parts":[[2020,1,27]],"date-time":"2020-01-27T12:06:50Z","timestamp":1580126810000},"page":"711-714","source":"Crossref","is-referenced-by-count":6,"title":["Increasing use of the Impella\u00ae-pump in severe cardiogenic shock: a word of caution"],"prefix":"10.1093","volume":"30","author":[{"given":"Sergey","family":"Vasin","sequence":"first","affiliation":[{"name":"Department of Cardiothoracic Surgery, University Medical Center Regensburg, Regensburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alois","family":"Philipp","sequence":"first","affiliation":[{"name":"Department of Cardiothoracic Surgery, University Medical Center Regensburg, Regensburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bernhard","family":"Floerchinger","sequence":"first","affiliation":[{"name":"Department of Cardiothoracic Surgery, University Medical Center Regensburg, Regensburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Priyank","family":"Rastogi","sequence":"first","affiliation":[{"name":"Department of Cardiothoracic Surgery, University Medical Center Regensburg, Regensburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dirk","family":"Lunz","sequence":"first","affiliation":[{"name":"Department of Anesthesiology, University Medical Center Regensburg, Regensburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Mueller","sequence":"first","affiliation":[{"name":"Department of Internal Medicine II, University Medical Center Regensburg, Regensburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christof","family":"Schmid","sequence":"first","affiliation":[{"name":"Department of Cardiothoracic Surgery, University Medical Center Regensburg, Regensburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniele","family":"Camboni","sequence":"first","affiliation":[{"name":"Department of Cardiothoracic Surgery, University Medical Center Regensburg, Regensburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2020,2,22]]},"reference":[{"key":"2020042503355389900_ivaa015-B1","doi-asserted-by":"crossref","first-page":"1287","DOI":"10.1056\/NEJMoa1208410","article-title":"Intraaortic balloon support for myocardial infarction with cardiogenic shock","volume":"367","author":"Thiele","year":"2012","journal-title":"N Engl J 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