{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,6]],"date-time":"2026-05-06T06:49:39Z","timestamp":1778050179989,"version":"3.51.4"},"reference-count":20,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2020,4,16]],"date-time":"2020-04-16T00:00:00Z","timestamp":1586995200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,7,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p\/>\n               <jats:sec>\n                  <jats:title>OBJECTIVES<\/jats:title>\n                  <jats:p>Patients with recurrent mitral regurgitation after surgical repair are currently treated with a re-repair procedure or valve replacement. The aim of this study was to compare outcomes of our series of patients who underwent re-repair versus replacement in this setting.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>METHODS<\/jats:title>\n                  <jats:p>From 2003 to 2017, a total of 79 patients with recurrent mitral regurgitation underwent re-repair, group A (39), or replacement, group B (40). Mean follow-up was 7.4\u2009\u00b1\u20093.27\u2009years (max 14.4). Inverse Probability of Treatment Weighting was used to create comparable distributions of the covariates; the Kaplan\u2013Meier method was used for survival and competing risk analysis for time to cardiac death, time to recurrence of MR \u22653+ and MR \u22652+.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>RESULTS<\/jats:title>\n                  <jats:p>A re-repair was possible in 49.4% of patients (39\/79). At hospital discharge, residual MR \u22652+ was present in 5 patients in group A, and none in group B (P\u2009&amp;lt;\u20090.001). The paired overall survival at 8\u2009years was 100% in the re-repair group and 96.5\u2009\u00b1\u20092.34% in the replacement group (P\u2009=\u20090.069). The cumulative incidence function of cardiac death, with non-cardiac death as competitive event, at 8\u2009years was 0% in group A and 3.5\u2009\u00b1\u20092.34% in group B (P\u2009=\u20090.077). The cumulative incidence function of MR \u22653+ at 8\u2009years was 29.2\u2009\u00b1\u20098.81% in group A and 0% in group B (P\u2009&amp;lt;\u20090.001).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>CONCLUSIONS<\/jats:title>\n                  <jats:p>Recurrent significant mitral regurgitation after re-repair is not rare already at 8\u2009years, but the survival tends to be worse after replacement. This finding calls for a very selective approach in pursuing a re-repair only when the intraoperative findings and the immediate results are very reassuring as far as long-term durability is concerned.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/icvts\/ivaa057","type":"journal-article","created":{"date-parts":[[2020,3,2]],"date-time":"2020-03-02T20:17:26Z","timestamp":1583180246000},"page":"35-41","source":"Crossref","is-referenced-by-count":6,"title":["Re-repair after previous mitral valve reconstruction: handle with care!"],"prefix":"10.1093","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2410-3218","authenticated-orcid":false,"given":"Cinzia","family":"Trumello","sequence":"first","affiliation":[{"name":"Division of Cardiac Surgery, IRCCS San Raffaele Scientific Institute, Milan, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ilaria","family":"Giambuzzi","sequence":"first","affiliation":[{"name":"Division of Cardiac Surgery, 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