{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T02:18:22Z","timestamp":1785291502421,"version":"3.55.0"},"reference-count":30,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2020,4,30]],"date-time":"2020-04-30T00:00:00Z","timestamp":1588204800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,7,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p\/>\n               <jats:sec>\n                  <jats:title>OBJECTIVES<\/jats:title>\n                  <jats:p>Risk factors for pneumothorax recurrence after videothoracoscopy for primary spontaneous pneumothorax are still being debated. The goal of this study was to assess whether the pleurodesis technique and other variables are possibly associated with the postoperative ipsilateral recurrence of pneumothorax.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>METHODS<\/jats:title>\n                  <jats:p>We retrospectively collected data of 1178 consecutive \u226440-year-old patients who underwent videothoracoscopy for primary spontaneous pneumothorax in 9 centres between 2007 and 2017. We excluded patients with hybrid pleurodesis and\/or incomplete follow-up, leaving for analysis 843 cases [80% men; median age (interquartile range) 22 (18\u201328) years]. Univariable and multivariable analyses were performed by logistic regression and tested by Cox regression model to assess factors related to ipsilateral pneumothorax recurrence including age, gender, body mass index, smoking habit, cannabis smoking, respiratory comorbidity, dystrophic severity score, surgical indication, videothoracoscopy port number and side, lung resection, pleurodesis technique and postoperative prolonged air leak (&amp;gt;5\u2009days).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>RESULTS<\/jats:title>\n                  <jats:p>Blebs\/bullae resection was performed in 664 (79%) patients. Pleurodesis was achieved by partial pleurectomy in 228 (27%) cases; by pleural electrocauterization in 176 (21%); by pleural abrasion in 121 (14%); and by talc poudrage in 318 (38%). During a median follow-up period of 70.0\u2009months (95% confidence interval 66.6\u201373.4), pneumothorax recurred in 79 patients (9.4%); among these, 29 underwent redo surgery; 34, chest drain\/talc slurry; and 16, clinicoradiological observation. The only independent risk factor for recurrence was postoperative prolonged air leak (P\u2009&amp;lt;\u20090.001) that was significantly related to blebs\/bullae resection (P\u2009=\u20090.03).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>CONCLUSIONS<\/jats:title>\n                  <jats:p>In this multicentric series, postoperative ipsilateral pneumothorax recurrence was remarkable and independently related to prolonged postoperative air leak; besides the retrospective study setting, the pleurodesis method did not have an impact on recurrence. To prevent prolonged air leak, blebs\/bullae treatment should be accurate and performed only if indicated.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/icvts\/ivaa064","type":"journal-article","created":{"date-parts":[[2020,3,20]],"date-time":"2020-03-20T20:10:14Z","timestamp":1584735014000},"page":"78-84","source":"Crossref","is-referenced-by-count":24,"title":["Analysis of pneumothorax recurrence risk factors in 843 patients who underwent videothoracoscopy for primary spontaneous pneumothorax: results of a multicentric study"],"prefix":"10.1093","volume":"31","author":[{"given":"Maria","family":"Cattoni","sequence":"first","affiliation":[{"name":"Center for Thoracic Surgery and Center for Minimally Invasive Surgery, Department of Medicine and Surgery, University of Insubria, Varese, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1325-9284","authenticated-orcid":false,"given":"Nicola","family":"Rotolo","sequence":"first","affiliation":[{"name":"Center for Thoracic Surgery and Center for Minimally Invasive Surgery, Department of Medicine and Surgery, University of Insubria, Varese, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Giovanna","family":"Mastromarino","sequence":"first","affiliation":[{"name":"Unit of Thoracic Surgery, Regional Hospital San Camillo-Forlanini, Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giuseppe","family":"Cardillo","sequence":"first","affiliation":[{"name":"Unit of Thoracic Surgery, Regional Hospital San Camillo-Forlanini, Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8571-121X","authenticated-orcid":false,"given":"Mario","family":"Nosotti","sequence":"first","affiliation":[{"name":"Thoracic Surgery and Lung Transplantation, Fondazione IRCCS Ca\u2019 Granda Ospedale Maggiore Policlinico, Milan, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4303-6244","authenticated-orcid":false,"given":"Paolo","family":"Mendogni","sequence":"first","affiliation":[{"name":"Thoracic Surgery and Lung Transplantation, Fondazione IRCCS Ca\u2019 Granda Ospedale Maggiore Policlinico, Milan, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandro","family":"Rizzi","sequence":"first","affiliation":[{"name":"Thoracic Surgery, ASST Santi Paolo e Carlo, Ospedale San Paolo, Milan, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2830-2783","authenticated-orcid":false,"given":"Federico","family":"Raveglia","sequence":"first","affiliation":[{"name":"Thoracic Surgery, ASST Santi Paolo e Carlo, Ospedale San Paolo, Milan, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandra","family":"Siciliani","sequence":"first","affiliation":[{"name":"Department of Thoracic Surgery, Sapienza University of Rome, Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erino A","family":"Rendina","sequence":"first","affiliation":[{"name":"Department of Thoracic Surgery, Sapienza University of Rome, Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucio","family":"Cagini","sequence":"first","affiliation":[{"name":"Department of Thoracic Surgery, University of Perugia Medical School, Perugia, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1521-7723","authenticated-orcid":false,"given":"Alberto","family":"Matricardi","sequence":"first","affiliation":[{"name":"Department of Thoracic Surgery, University of Perugia Medical School, Perugia, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pier Luigi","family":"Filosso","sequence":"first","affiliation":[{"name":"Department of Thoracic Surgery, Azienda Ospedaliera Universitaria Citt\u00e0 della Salute e della Scienza di Torino, Turin, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erika","family":"Passone","sequence":"first","affiliation":[{"name":"Department of Thoracic Surgery, Azienda Ospedaliera Universitaria Citt\u00e0 della Salute e della Scienza di Torino, Turin, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefano","family":"Margaritora","sequence":"first","affiliation":[{"name":"Department of General Thoracic Surgery, Fondazione Policlinico Universitario \u201cA. Gemelli\u201d, IRCCS, Universit\u00e0 Cattolica del Sacro Cuore, Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Letizia","family":"Vita","sequence":"first","affiliation":[{"name":"Department of General Thoracic Surgery, Fondazione Policlinico Universitario \u201cA. Gemelli\u201d, IRCCS, Universit\u00e0 Cattolica del Sacro Cuore, Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6267-0099","authenticated-orcid":false,"given":"Pietro","family":"Bertoglio","sequence":"first","affiliation":[{"name":"Division of Thoracic Surgery, IRCCS, Sacro Cuore-Don Calabria Hospital, Negrar di Valpolicella, Verona, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3867-9429","authenticated-orcid":false,"given":"Andrea","family":"Viti","sequence":"first","affiliation":[{"name":"Division of Thoracic Surgery, IRCCS, Sacro Cuore-Don Calabria Hospital, Negrar di Valpolicella, Verona, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6281-1800","authenticated-orcid":false,"given":"Andrea","family":"Imperatori","sequence":"first","affiliation":[{"name":"Center for Thoracic Surgery and Center for Minimally Invasive Surgery, Department of Medicine and Surgery, University of Insubria, Varese, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2020,4,30]]},"reference":[{"key":"2020070114041412200_ivaa064-B1","doi-asserted-by":"crossref","first-page":"590","DOI":"10.1378\/chest.119.2.590","article-title":"Management of spontaneous pneumothorax: an American College of Chest Physicians Delphi consensus statement","volume":"119","author":"Baumann","year":"2001","journal-title":"Chest"},{"key":"2020070114041412200_ivaa064-B2","doi-asserted-by":"crossref","first-page":"ii18","DOI":"10.1136\/thx.2010.136986","article-title":"Management of spontaneous pneumothorax: British Thoracic Society Pleural Disease Guideline 2010","volume":"65","author":"MacDuff","year":"2010","journal-title":"Thorax"},{"key":"2020070114041412200_ivaa064-B3","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1183\/09031936.00219214","article-title":"ERS task 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