{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T02:39:59Z","timestamp":1790476799998,"version":"4.1.0"},"reference-count":22,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2020,11,22]],"date-time":"2020-11-22T00:00:00Z","timestamp":1606003200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,1,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p\/>\n               <jats:sec>\n                  <jats:title>OBJECTIVES<\/jats:title>\n                  <jats:p>Despite promising short- and mid-term results for durability of the Trifecta valve, contradictory reports of early structural valve deterioration (SVD) do exist. We investigated the incidence of SVD after surgical aortic valve replacement (SAVR) with the Trifecta in our single-centre experience.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>METHODS<\/jats:title>\n                  <jats:p>Data of 347 consecutive patients (mean age 71.6\u2009\u00b1\u20099.5\u2009years, 63.4% male) undergoing SAVR with the Trifecta between 2011 and 2017 were analysed. Clinical and echocardiographic reports were obtained with a median follow-up of 41\u2009months (1114 patient years).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>RESULTS<\/jats:title>\n                  <jats:p>Isolated SAVR was performed in 122 patients (35.2%), whereas 225 patients (64.8%) underwent concomitant procedures. The median EuroSCORE II was 4.0 (0.9; 7.1) and 30-day mortality was 3.7% (n\u2009=\u200913). Kaplan\u2013Meier estimates for the freedom of overall mortality at 1, 5 and 7 years were 88.7\u2009\u00b1\u20091.7%, 73.7\u2009\u00b1\u20092.6% and 64.7\u2009\u00b1\u20094.2%, respectively. SVD was observed in 25 patients (7.2%) with a median time to first diagnosis of 73\u2009months. Freedom of SVD was 92.5\u2009\u00b1\u20090.9% at 5 years and 65.5\u2009\u00b1\u20097.1% at 7 years. Thirteen patients underwent reintervention for SVD (6 re-SAVR, 7 valve-in-valve), resulting in a freedom of reintervention for the SVD of 98.5\u2009\u00b1\u20091.1% at 5 years and 76.9\u2009\u00b1\u20096.9% at 7 years.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>CONCLUSIONS<\/jats:title>\n                  <jats:p>We herein report one of the highest rates of SVD after SAVR with the Trifecta. These data indicate that the durability of the prosthesis decreases at intermediate to long-term follow-up, leading to considerable rates of reintervention due to SVD.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/icvts\/ivaa236","type":"journal-article","created":{"date-parts":[[2020,9,21]],"date-time":"2020-09-21T19:21:43Z","timestamp":1600716103000},"page":"39-46","source":"Crossref","is-referenced-by-count":16,"title":["Structural valve deterioration after aortic valve replacement with the Trifecta valve"],"prefix":"10.1093","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0925-6160","authenticated-orcid":false,"given":"Paul","family":"Werner","sequence":"first","affiliation":[{"name":"Division of Cardiac Surgery, Department of Surgery, Medical University of Vienna, Vienna, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jasmin","family":"Gritsch","sequence":"additional","affiliation":[{"name":"Division of Cardiac Surgery, Department of Surgery, Medical University of Vienna, Vienna, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sabine","family":"Scherzer","sequence":"additional","affiliation":[{"name":"Division of Cardiac Surgery, Department of Surgery, Medical University of Vienna, Vienna, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1583-5783","authenticated-orcid":false,"given":"Christoph","family":"Gross","sequence":"additional","affiliation":[{"name":"Division of Cardiac Surgery, Department of Surgery, Medical University of Vienna, Vienna, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9843-2925","authenticated-orcid":false,"given":"Marco","family":"Russo","sequence":"additional","affiliation":[{"name":"Division of Cardiac Surgery, Department of Surgery, Medical University of Vienna, Vienna, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Iuliana","family":"Coti","sequence":"additional","affiliation":[{"name":"Division of Cardiac Surgery, Department of Surgery, Medical University of Vienna, Vienna, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2818-2227","authenticated-orcid":false,"given":"Alfred","family":"Kocher","sequence":"additional","affiliation":[{"name":"Division of Cardiac Surgery, Department of Surgery, Medical University of Vienna, Vienna, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7257-110X","authenticated-orcid":false,"given":"Guenther","family":"Laufer","sequence":"additional","affiliation":[{"name":"Division of Cardiac Surgery, Department of Surgery, Medical University of Vienna, Vienna, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4950-5432","authenticated-orcid":false,"given":"Martin","family":"Andreas","sequence":"additional","affiliation":[{"name":"Division of Cardiac Surgery, Department of Surgery, Medical University of Vienna, Vienna, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2020,11,22]]},"reference":[{"key":"2022030919150795000_ivaa236-B1","doi-asserted-by":"crossref","first-page":"1262","DOI":"10.1016\/j.jtcvs.2015.01.052","article-title":"National trends in utilization and in-hospital outcomes of mechanical versus bioprosthetic aortic valve replacements","volume":"149","author":"Isaacs","year":"2015","journal-title":"J Thorac Cardiovasc Surg"},{"key":"2022030919150795000_ivaa236-B2","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1161\/01.CIR.95.2.479","article-title":"Prevention of bioprosthetic heart valve calcification by ethanol preincubation. 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