{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T04:31:08Z","timestamp":1790829068117,"version":"4.1.0"},"reference-count":22,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2020,11,19]],"date-time":"2020-11-19T00:00:00Z","timestamp":1605744000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,1,22]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p\/>\n               <jats:sec>\n                  <jats:title>OBJECTIVES<\/jats:title>\n                  <jats:p>Left ventricular assist device (LVAD) implantation for end-stage heart failure patients has been on the rise, providing a reliable long-term option. For some LVAD patients, longer term LV unloading leads to recovery; hence, the need for evaluating potential myocardial recovery and weaning eligibility has emerged.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>METHODS<\/jats:title>\n                  <jats:p>All patients who underwent contemporary LVAD explantation at our institution between 2009 and 2020 were included in the study. Patients in New York Heart Association I, left ventricular ejection fraction &amp;gt;40%, a cardiac index &amp;gt;2.4\u2009l\/min and a peak oxygen intake &amp;gt;50% predicted underwent a 4-phase weaning assessment. A minimally invasive approach using a titanium plug was the surgery of choice in the most recent explants. Kaplan\u2013Meier curves were used to estimate the survival at 1 and 5\u2009years.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>RESULTS<\/jats:title>\n                  <jats:p>Twenty-six patients (17 HeartMate II, 9 HeartWare) underwent LVAD explantation after a median 317\u2009days of support [IQ (212\u2013518)], range 131\u20131437. Mean age at explant was 35.8\u2009\u00b1\u200912.7\u2009years and 85% were males. Idiopathic dilated cardiomyopathy was the underlying diagnosis in 70% of cases. Thirteen (48%) patients were on short-term mechanical circulatory support and 60% required intensive care unit admission prior to the LVAD implantation. At 1\u2009year, Kaplan\u2013Meier estimated survival was 88%, whereas at 6\u2009years, it was 77%. The average left ventricular ejection fraction at 1 year post-explant was 44.25% \u00b1 8.44.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>CONCLUSIONS<\/jats:title>\n                  <jats:p>The use of a standardized weaning protocol (echocardiographic and invasive) and a minimally invasive LVAD explant technique minimizes periprocedural complications and leads to good long-term device-free survival rates.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/icvts\/ivaa259","type":"journal-article","created":{"date-parts":[[2020,10,10]],"date-time":"2020-10-10T19:09:29Z","timestamp":1602356969000},"page":"298-305","source":"Crossref","is-referenced-by-count":19,"title":["A detailed explantation assessment protocol for patients with left ventricular assist devices with myocardial 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