{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,13]],"date-time":"2026-06-13T14:58:02Z","timestamp":1781362682155,"version":"3.54.1"},"reference-count":14,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2020,12,13]],"date-time":"2020-12-13T00:00:00Z","timestamp":1607817600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,4,19]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>OBJECTIVES<\/jats:title>\n                  <jats:p>Our goal was to evaluate the impact of the adult congenital heart disease anatomical and physiological (ACHD AP) classification system on the surgical management of Ebstein anomaly (EA) in adult patients.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>METHODS<\/jats:title>\n                  <jats:p>From February 2000 through August 2017, data of patients aged at least 16\u2009years, who underwent primary EA surgery, were retrospectively evaluated. The cohort was divided in 2 groups according to their ACHD AP classification: the moderate EA group (IIB, IIC) and the severe EA group (IID). Survival, freedom from reoperation and freedom from occurrence of major adverse advents were estimated.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>RESULTS<\/jats:title>\n                  <jats:p>There were 33 patients (21 women, 12 men). Eighteen belonged to the moderate group, 15 to the severe group. There were 12 female patients (80%) in the severe group. Patients in the moderate group were younger than those in the severe group (P\u2009=\u20090.02): 32\u2009\u00b1\u200912 vs 44\u2009\u00b1\u200915\u2009years old. Thirty tricuspid valve repairs and 3 replacements were performed. Repair was mainly performed in the moderate group (P\u2009=\u20090.02). Overall survival was 90.1 \u00b1 5.4% at 9\u2009months after the operation and did not change in the later follow-up period. It was 100% for patients in the moderate group and 80.0 \u00b1 10.3% in the severe group (P\u2009=\u20090.07), and 75.0 \u00b1 12.5% for female patients of in the severe group compared to 100% for the remaining patients (P\u2009=\u20090.025). Survival free from major adverse events, including reoperation, at 10\u2009years was 60.0 \u00b1 12.6% in the moderate and 38.1% \u00b1 12.9% in the severe group (P\u2009=\u20090.03). No patient in the moderate group evolved to be in the severe group at late follow-up.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>CONCLUSION<\/jats:title>\n                  <jats:p>Adult EA patients should undergo surgery earlier when they are still in the moderate ACHD AP classification.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/icvts\/ivaa294","type":"journal-article","created":{"date-parts":[[2020,10,28]],"date-time":"2020-10-28T20:12:23Z","timestamp":1603915943000},"page":"593-600","source":"Crossref","is-referenced-by-count":9,"title":["Surgical management of Ebstein anomaly: impact of the adult congenital heart disease anatomical and physiological classifications"],"prefix":"10.1093","volume":"32","author":[{"given":"Laura","family":"Homzova","sequence":"first","affiliation":[{"name":"Department of Congenital Heart Surgery \u2013 Pediatric Heart Surgery, German Heart Center Berlin, Berlin, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3140-9154","authenticated-orcid":false,"given":"Joachim","family":"Photiadis","sequence":"additional","affiliation":[{"name":"Department of Congenital Heart Surgery \u2013 Pediatric Heart Surgery, German Heart Center Berlin, Berlin, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9207-8010","authenticated-orcid":false,"given":"Nicod\u00e8me","family":"Sinzobahamvya","sequence":"additional","affiliation":[{"name":"Department of Congenital Heart Surgery \u2013 Pediatric Heart Surgery, German Heart Center Berlin, Berlin, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stanislav","family":"Ovroutski","sequence":"additional","affiliation":[{"name":"Department of Congenital Heart Disease \u2013 Pediatric Cardiology, German Heart Center Berlin, Berlin, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mi-Young","family":"Cho","sequence":"additional","affiliation":[{"name":"Department of Congenital Heart Surgery \u2013 Pediatric Heart Surgery, German Heart Center Berlin, Berlin, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9155-9509","authenticated-orcid":false,"given":"Antonia","family":"Schulz","sequence":"additional","affiliation":[{"name":"Department of Congenital Heart Surgery \u2013 Pediatric Heart Surgery, German Heart Center Berlin, Berlin, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2020,12,13]]},"reference":[{"key":"2022030919170670800_ivaa294-B1","doi-asserted-by":"crossref","first-page":"1890","DOI":"10.1016\/S0735-1097(02)01886-7","article-title":"The incidence of congenital heart disease","volume":"39","author":"Hoffman","year":"2002","journal-title":"J Am Coll 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