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Histopathological examinations of the resected anastomotic tissue revealed intimal hyperplasia at the anastomotic site. Predominant lesion cells were identified as myofibroblasts and had the characteristics of fibroblasts and synthetic smooth muscle cells. These cells could be a useful target for preventing anastomotic stenosis after total anomalous pulmonary vein connection repair.<\/jats:p>","DOI":"10.1093\/icvts\/ivab007","type":"journal-article","created":{"date-parts":[[2021,1,29]],"date-time":"2021-01-29T20:11:36Z","timestamp":1611951096000},"page":"998-1000","source":"Crossref","is-referenced-by-count":1,"title":["Histopathology of anastomotic stenosis after total anomalous pulmonary vein connection"],"prefix":"10.1093","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0198-6495","authenticated-orcid":false,"given":"Naoki","family":"Masaki","sequence":"first","affiliation":[{"name":"Department of Cardiovascular Surgery, Miyagi Children\u2019s Hospital, Sendai, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3476-2869","authenticated-orcid":false,"given":"Masahiro","family":"Mizumoto","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Miyagi Children\u2019s Hospital, Sendai, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Osamu","family":"Adachi","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Miyagi Children\u2019s Hospital, Sendai, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sadahiro","family":"Sai","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Miyagi Children\u2019s Hospital, Sendai, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2021,2,3]]},"reference":[{"key":"2021052808395723700_ivab007-B1","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1016\/S0022-5223(99)70287-4","article-title":"Surgical management of progressive pulmonary venous obstruction after repair of total anomalous pulmonary venous connection","volume":"117","author":"Lacour-Gayet","year":"1999","journal-title":"J Thorac Cardiovasc Surg"},{"key":"2021052808395723700_ivab007-B2","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1016\/S0002-9149(00)01022-5","article-title":"Mechanism of pulmonary vein stenosis in infants with normally connected veins","volume":"86","author":"Sadr","year":"2000","journal-title":"Am J Cardiol"},{"key":"2021052808395723700_ivab007-B3","doi-asserted-by":"crossref","first-page":"1198","DOI":"10.1097\/PAS.0000000000000892","article-title":"Paucicellular fibrointimal proliferation characterizes pediatric pulmonary vein stenosis: clinicopathologic analysis of 213 samples from 97 patients","volume":"41","author":"Kovach","year":"2017","journal-title":"Am J Surg Pathol"},{"key":"2021052808395723700_ivab007-B4","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1016\/j.jtcvs.2020.01.098","article-title":"Progression of vascular remodeling in pulmonary vein obstruction","volume":"160","author":"Masaki","year":"2020","journal-title":"J Thorac Cardiovasc Surg"}],"container-title":["Interactive CardioVascular and Thoracic Surgery"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/icvts\/article-pdf\/32\/6\/998\/38338186\/ivab007.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/academic.oup.com\/icvts\/article-pdf\/32\/6\/998\/38338186\/ivab007.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,5,28]],"date-time":"2021-05-28T08:51:15Z","timestamp":1622191875000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/icvts\/article\/32\/6\/998\/6126910"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,2,3]]},"references-count":4,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2021,2,3]]},"published-print":{"date-parts":[[2021,5,27]]}},"URL":"https:\/\/doi.org\/10.1093\/icvts\/ivab007","relation":{},"ISSN":["1569-9285"],"issn-type":[{"value":"1569-9285","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2021,6,1]]},"published":{"date-parts":[[2021,2,3]]}}}