{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,20]],"date-time":"2026-04-20T10:47:57Z","timestamp":1776682077957,"version":"3.51.2"},"reference-count":10,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2021,4,24]],"date-time":"2021-04-24T00:00:00Z","timestamp":1619222400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,6,28]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>The most frequent cause of suboptimal results in a parathyroid adenoma resection is an ectopic location, mainly in the anterior mediastinum. These cases may not always be resected through a traditional cervical access. We present 2 cases of primary hyperparathyroidism who underwent an unsuccessful bilateral cervical exploration due to parathyroid tissue located inside the thymic gland. A video-assisted thoracoscopic surgery thymectomy with intraoperative determination of blood parathormone levels was performed. A 50% reduction of intraoperatory parathyroid hormone blood from the highest basal level at 5 and 10\u2009min after resection was obtained. Final pathological results showed an intra-thymic parathyroid adenoma in the first patient and an intra-thymic focus of parathyroid hyperplasia in the second patient. In conclusion, video-assisted thoracoscopic surgery thymectomy could be the optimal approach to resect ectopic parathyroid adenomas located in the anterior mediastinum.<\/jats:p>","DOI":"10.1093\/icvts\/ivab043","type":"journal-article","created":{"date-parts":[[2021,1,23]],"date-time":"2021-01-23T15:49:10Z","timestamp":1611416950000},"page":"82-84","source":"Crossref","is-referenced-by-count":2,"title":["What to do when the parathyroid gland is not found during a transcervical exploration?"],"prefix":"10.1093","volume":"33","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3774-8173","authenticated-orcid":false,"given":"Georgina","family":"\u00a0Planas","sequence":"first","affiliation":[{"name":"Department of Thoracic Surgery, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3370-0869","authenticated-orcid":false,"given":"Juan Carlos","family":"Trujillo-Reyes","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain"},{"name":"Department of Surgery, Universitat Autonoma de Barcelona, Barcelona, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mauro","family":"Guarino","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5144-2963","authenticated-orcid":false,"given":"Elisabeth","family":"Mart\u00ednez-T\u00e9llez","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain"},{"name":"Department of Surgery, Universitat Autonoma de Barcelona, Barcelona, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Esther","family":"Cladellas","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jose Ignacio","family":"P\u00e9rez","sequence":"additional","affiliation":[{"name":"Department of Endocrine and General Surgery, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5551-0145","authenticated-orcid":false,"given":"Antonio","family":"Moral","sequence":"additional","affiliation":[{"name":"Department of Surgery, Universitat Autonoma de Barcelona, Barcelona, Spain"},{"name":"Department of Endocrine and General Surgery, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9","family":"Belda","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain"},{"name":"Department of Surgery, Universitat Autonoma de Barcelona, Barcelona, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2021,4,24]]},"reference":[{"key":"2022031517055158300_ivab043-B1","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1016\/j.amjsurg.2005.10.049","article-title":"Incidence and location of ectopic abnormal parathyroid glands","volume":"191","author":"Phitayakorn","year":"2006","journal-title":"Am J Surg"},{"key":"2022031517055158300_ivab043-B2","first-page":"1374","volume-title":"Schwartz\u2019s Principles of Surgery","author":"Lal","year":"2010"},{"key":"2022031517055158300_ivab043-B3","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1016\/j.amjsurg.2008.07.022","article-title":"Reoperative parathyroidectomy in 228 patients during the era of minimal-access surgery and intraoperative parathyroid hormone monitoring","volume":"196","author":"Richards","year":"2008","journal-title":"Am J Surg"},{"key":"2022031517055158300_ivab043-B4","doi-asserted-by":"crossref","first-page":"2700","DOI":"10.1007\/s00330-017-5190-4","article-title":"Benefit of 18F-fluorocholine PET imaging in parathyroid surgery","volume":"28","author":"Huber","year":"2018","journal-title":"Eur Radiol"},{"key":"2022031517055158300_ivab043-B5","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1148\/radiol.2019182122","article-title":"Diagnostic performance of 4D CT and Sestamibi SPECT\/CT in localizing parathyroid adenomas in primary hyperparathyroidism","volume":"291","author":"Yeh","year":"2019","journal-title":"Radiology"},{"key":"2022031517055158300_ivab043-B6","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1186\/s12893-019-0641-2","article-title":"Thoracoscopic surgical case of an ectopic mediastinal parathyroid adenoma detected by chance: a case report","volume":"19","author":"Mitsuboshi","year":"2019","journal-title":"BMC Surg"},{"key":"2022031517055158300_ivab043-B7","year":"2007"},{"key":"2022031517055158300_ivab043-B8","doi-asserted-by":"crossref","first-page":"174","DOI":"10.21037\/acs.2019.02.04","article-title":"A systematic review of robotic versus open and video assisted thoracoscopic surgery (VATS) approaches for thymectomy","volume":"8","author":"O\u2019Sullivan","year":"2019","journal-title":"Ann Cardiothorac Surg"},{"key":"2022031517055158300_ivab043-B9","first-page":"1","article-title":"Intraoperative scintigraphy using a large field-of-view portable gamma camera for primary hyperparathyroidism: initial experience","volume":"2015","author":"Hall","year":"2015","journal-title":"Biomed Res Int"},{"key":"2022031517055158300_ivab043-B10","first-page":"145749691987758","article-title":"Indocyanine green fluorescence angiography can guide intraoperative localization during parathyroid surgery","volume":"25","author":"Di Meo","year":"2019","journal-title":"Scand J Surg"}],"container-title":["Interactive CardioVascular and Thoracic Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/icvts\/article-pdf\/33\/1\/82\/42900278\/ivab043.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/icvts\/article-pdf\/33\/1\/82\/42900278\/ivab043.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,15]],"date-time":"2022-03-15T17:09:13Z","timestamp":1647364153000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/icvts\/article\/33\/1\/82\/6248205"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,4,24]]},"references-count":10,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2021,4,24]]},"published-print":{"date-parts":[[2021,6,28]]}},"URL":"https:\/\/doi.org\/10.1093\/icvts\/ivab043","relation":{},"ISSN":["1569-9285"],"issn-type":[{"value":"1569-9285","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2021,7,1]]},"published":{"date-parts":[[2021,4,24]]}}}