{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T19:22:17Z","timestamp":1790018537310,"version":"4.0.1"},"reference-count":23,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2021,5,13]],"date-time":"2021-05-13T00:00:00Z","timestamp":1620864000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"DOI":"10.13039\/100013410","name":"LivaNova","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100013410","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,7,26]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>OBJECTIVES<\/jats:title><jats:p>Sutureless aortic valve prostheses have been introduced to facilitate the implant process, speed up the operating time and improve haemodynamic performance. The goal of this study was to assess the potential advantages of using sutureless prostheses during minimally invasive aortic valve replacement in a large multicentre population.<\/jats:p><\/jats:sec><jats:sec><jats:title>METHODS<\/jats:title><jats:p>From 2011 to 2019, a total of 3402 patients in 11 hospitals underwent isolated aortic valve replacement with minimal access approaches using a bioprosthesis. A total of 475 patients received sutureless valves; 2927 received standard valves. The primary outcome was the incidence of 30-day deaths. Secondary outcomes were the occurrence of major complications following procedures performed with sutureless or standard bioprostheses. Propensity matched comparisons was performed based on a multivariable logistic regression model.<\/jats:p><\/jats:sec><jats:sec><jats:title>RESULTS<\/jats:title><jats:p>The annual number of sutureless valve implants increased over the years. The matching procedure paired 430 sutureless with 860 standard aortic valve replacements. A total of 0.7% and 2.1% patients with sutureless and standard prostheses, respectively, died within 30\u2009days (P\u2009=\u20090.076). Cross-clamp times [48 (40\u201362) vs 63\u2009min (48\u201374); P\u2009=\u20090.001] and need for blood transfusions (27.4% vs 33.5%; P\u2009=\u20090.022) were lower in patients with sutureless valves. No difference in permanent pacemaker insertions was observed in the overall population (3.3% vs 4.4% in the standard and sutureless groups; P\u2009=\u20090.221) and in the matched groups (3.6% vs 4.7% in the standard and sutureless groups; P\u2009=\u20090.364).<\/jats:p><\/jats:sec><jats:sec><jats:title>CONCLUSIONS<\/jats:title><jats:p>The use of sutureless prostheses is advantageous and facilitates the adoption of a minimally invasive approach, reducing cardiac arrest time and the number of blood transfusions. No increased risk of permanent pacemaker insertion was observed.<\/jats:p><\/jats:sec>","DOI":"10.1093\/icvts\/ivab070","type":"journal-article","created":{"date-parts":[[2021,2,22]],"date-time":"2021-02-22T20:10:56Z","timestamp":1614024656000},"page":"188-194","source":"Crossref","is-referenced-by-count":14,"title":["Minimally invasive aortic valve replacement: short-term efficacy of sutureless compared with stented bioprostheses"],"prefix":"10.1093","volume":"33","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2261-7098","authenticated-orcid":false,"given":"Domenico","family":"Paparella","sequence":"first","affiliation":[{"name":"Department of Cardiac Surgery, Santa Maria Hospital, GVM Care & Research, Bari, Italy"},{"name":"Dipartimento Scienze Medice e Chirurgiche, Universit\u00e0 di Foggia, Foggia, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4913-9834","authenticated-orcid":false,"given":"Giuseppe","family":"Santarpino","sequence":"additional","affiliation":[{"name":"Cardiac Surgery Unit, Department of Experimental and Clinical Medicine, Magna Graecia University, Catanzaro, Italy"},{"name":"Department of Cardiac Surgery, Klinikum N\u00fcrnberg, Paracelsus Medical University, Nuremberg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8373-8486","authenticated-orcid":false,"given":"Marco","family":"Moscarelli","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery, Anthea Hospital, GVM Care & Research, Bari, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6936-350X","authenticated-orcid":false,"given":"Pietro","family":"Guida","sequence":"additional","affiliation":[{"name":"Regional General Hospital \u201cF. Miulli\u201d, Acquaviva delle Fonti, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adriano","family":"De Santis","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery, Santa Maria Hospital, GVM Care & Research, Bari, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Khalil","family":"Fattouch","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery, Maria Eleonora Hospital, GVM Care & Research, Palermo, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luigi","family":"Martinelli","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery, ICLAS, GVM Care & Research, Rapallo, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberto","family":"Coppola","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery, ICLAS, GVM Care & Research, Rapallo, 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