{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,16]],"date-time":"2026-02-16T09:07:44Z","timestamp":1771232864234,"version":"3.50.1"},"reference-count":26,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2021,4,1]],"date-time":"2021-04-01T00:00:00Z","timestamp":1617235200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,7,26]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p\/>\n               <jats:sec>\n                  <jats:title>OBJECTIVES<\/jats:title>\n                  <jats:p>This study aims to evaluate the efficacy, safety and long-term outcomes of a renoprotective non-contrast, transoesophageal echocardiography-guided transapical (TA) transcatheter aortic valve replacement (TAVR) strategy with a balloon-expandable prosthesis, as well as to determine its impact on renal function.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>METHODS<\/jats:title>\n                  <jats:p>Between 2009 and 2019, 200 consecutive patients underwent a non-contrast, transoesophageal echocardiography-guided TA TAVR with a balloon-expandable prosthesis.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>RESULTS<\/jats:title>\n                  <jats:p>The device success rate was 95.5%. Transoesophageal echocardiography-guided deployment demonstrated a low rate of procedure-related complications: 9.5% of acute kidney injury, 8% postoperative bleeding, 6% low-cardiac output, 4.5% postprocedural aortic regurgitation \u2265+2, 4% implantation of permanent pacemaker and 2% stroke. There were no significant differences between preoperative and on discharge estimated glomerular filtration rate (53.9\u2009\u00b1\u200922.2 vs 54.3\u2009\u00b1\u200922.9\u2009ml\/min\/1.73 m2, P\u2009=\u20090.60). Logistic regression analysis confirmed postoperative bleeding as an independent predictor for acute kidney injury (odds ratio (OR) 11.148, 95% confidence interval 3.537\u201335.140, P\u2009&amp;lt;\u20090.001). In-hospital mortality was 7.5%. The mean follow-up was 48.5\u2009\u00b1\u200939.9\u2009months. Renal function and patient\u2019s chronic kidney disease stage did not significantly vary during follow-up. Long-term cumulative survival at 1, 5 and 10\u2009years was 84.2\u2009\u00b1\u20090.027%, 42.9\u2009\u00b1\u20090.038% and 32.5\u2009\u00b1\u20090.044%, respectively. Renal function affected on neither in-hospital mortality nor long-term survival.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>CONCLUSIONS<\/jats:title>\n                  <jats:p>Non-contrast, transoesophageal echocardiography-guided TA TAVR is a safe and reproducible technique with a low incidence of periprocedural complications that avoids the use of contrast and mitigates the incidence of acute kidney injury.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/icvts\/ivab080","type":"journal-article","created":{"date-parts":[[2021,2,26]],"date-time":"2021-02-26T12:20:50Z","timestamp":1614342050000},"page":"195-202","source":"Crossref","is-referenced-by-count":5,"title":["Non-contrast transoesophageal echo-guided transapical transcatheter aortic valve replacement: 10-year experience of a renoprotective strategy"],"prefix":"10.1093","volume":"33","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1483-9037","authenticated-orcid":false,"given":"Victor X","family":"Mosquera","sequence":"first","affiliation":[{"name":"Department of Cardiac Surgery, Complejo Hospitalario Universitario de A Coru\u00f1a, A Coru\u00f1a, Spain"},{"name":"Instituto de Investigaci\u00f3n Biom\u00e9dica de A Coru\u00f1a (INIBIC), A Coru\u00f1a, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2741-732X","authenticated-orcid":false,"given":"Alberto","family":"Bouzas-Mosquera","sequence":"additional","affiliation":[{"name":"Instituto de Investigaci\u00f3n Biom\u00e9dica de A Coru\u00f1a (INIBIC), A Coru\u00f1a, Spain"},{"name":"Department of Cardiology, Complejo Hospitalario Universitario de A Coru\u00f1a, A Coru\u00f1a, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yago","family":"Vilela-Gonz\u00e1lez","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery, Complejo Hospitalario Universitario de A Coru\u00f1a, A Coru\u00f1a, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B\u00e1rbara","family":"Oujo-Gonz\u00e1lez","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery, Complejo Hospitalario Universitario de A Coru\u00f1a, A Coru\u00f1a, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlos","family":"Velasco-Garc\u00eda","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery, Complejo Hospitalario Universitario de A Coru\u00f1a, A Coru\u00f1a, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1480-6027","authenticated-orcid":false,"given":"Jos\u00e9 J","family":"Cuenca-Castillo","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery, Complejo Hospitalario Universitario de A Coru\u00f1a, A Coru\u00f1a, Spain"},{"name":"Instituto de Investigaci\u00f3n Biom\u00e9dica de A Coru\u00f1a (INIBIC), A Coru\u00f1a, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9 M","family":"Herrera-Nore\u00f1a","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery, Complejo Hospitalario Universitario de A Coru\u00f1a, A Coru\u00f1a, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2021,4,1]]},"reference":[{"key":"2022030915262143000_ivab080-B1","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1002\/ccd.21207","article-title":"Contrast-induced nephropathy","volume":"71","author":"Pucelikova","year":"2008","journal-title":"Catheter Cardiovasc 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