{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T23:22:37Z","timestamp":1787008957609,"version":"build-2736575974"},"reference-count":21,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2021,6,13]],"date-time":"2021-06-13T00:00:00Z","timestamp":1623542400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,8,18]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>\u2002<\/jats:title>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>OBJECTIVES<\/jats:title>\n                    <jats:p>The Ross procedure is an attractive option for the management of aortic valve disease in paediatric patients. We reviewed our experience with the paediatric Ross procedure to determine survival and freedom from reoperation in the third decade after surgery.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS<\/jats:title>\n                    <jats:p>We reviewed the data of 124 paediatric patients [71% male, median age at time of surgery 11.1\u2009years (interquartile range 6\u201314.8\u2009years); 63.7% bicuspid aortic valve], who underwent the Ross procedure at 2 tertiary centres from April 1991 to April 2020. The Ross-Konno procedures were performed on 14 (11.3%) patients. Deaths were cross-checked with the national health insurance database, and survival status was available for 96.8% of the patients. The median follow-up time was 12.1\u2009years (interquartile range 3\u201318\u2009years).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS<\/jats:title>\n                    <jats:p>There were 3 early and 6 late deaths. All early deaths occurred in patients aged &amp;lt;1\u2009year at the time of surgery. The 25-year survival was 90.3%. Actuarial freedom from reoperation (linearized rates in parentheses) was as follows: Autograft reoperation was 90.8% (0.48%\/patient-year) and right ventricular outflow tract (RVOT) reoperation was 67% (2.07%\/patient year) at 25\u2009years. The univariable Cox-proportional hazard analysis revealed younger age at time of surgery (P\u2009&amp;lt;\u20090.001), smaller implanted valve size (P\u2009&amp;lt;\u20090.001) and the use of a xenograft rather than a homograft (P\u2009&amp;lt;\u20090.001) as predictors of RVOT reoperation. At multivariable Cox-proportional hazard analysis, only age was an independent risk factor for RVOT reoperation (P\u2009=\u20090.041).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSIONS<\/jats:title>\n                    <jats:p>The Ross and the Ross-Konno procedures are associated with good outcomes in paediatric patients. Reoperation of the RVOT is frequent and associated with younger age.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/icvts\/ivab093","type":"journal-article","created":{"date-parts":[[2021,4,18]],"date-time":"2021-04-18T15:06:48Z","timestamp":1618758408000},"page":"455-461","source":"Crossref","is-referenced-by-count":10,"title":["Long-term outcomes after the paediatric Ross and Ross-Konno procedures"],"prefix":"10.1093","volume":"33","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8426-5038","authenticated-orcid":false,"given":"Johanna","family":"Schlein","sequence":"first","affiliation":[{"name":"Department of Cardiac Surgery, Medical University of Vienna, Vienna, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barbara Elisabeth","family":"Ebner","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Pulmonology, Allergology, and Cystic Fibrosis, Department of Pediatrics III, Innsbruck Medical University, Innsbruck, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ralf","family":"Geiger","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Pulmonology, Allergology, and Cystic Fibrosis, Department of Pediatrics III, Innsbruck Medical University, Innsbruck, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2932-5074","authenticated-orcid":false,"given":"Paul","family":"Simon","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery, Medical University of Vienna, Vienna, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gregor","family":"Wollenek","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery, Medical University of Vienna, Vienna, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anton","family":"Moritz","sequence":"additional","affiliation":[{"name":"Department of Thoracic and Cardiovascular Surgery, Johann Wolfgang Goethe University, Frankfurt am Main, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas","family":"Gamillscheg","sequence":"additional","affiliation":[{"name":"Division of Pediatric Cardiology, Department of Pediatrics, Medical University Graz, Graz, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eva","family":"Base","sequence":"additional","affiliation":[{"name":"Division of Cardiac Thoracic Vascular Anaesthesia and Intensive Care Medicine, Department of Anaesthesia, Intensive Care Medicine and Pain Medicine, Medical University of Vienna, Vienna, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G\u00fcnther","family":"Laufer","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery, Medical University of Vienna, Vienna, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2185-4895","authenticated-orcid":false,"given":"Daniel","family":"Zimpfer","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery, Medical University of Vienna, Vienna, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2021,6,13]]},"reference":[{"key":"2022030915261889600_ivab093-B1","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1016\/S0140-6736(10)60828-8","article-title":"Long-term outcomes after autograft versus homograft aortic root replacement in adults with aortic valve disease: a randomised controlled trial","volume":"376","author":"El-Hamamsy","year":"2010","journal-title":"Lancet"},{"key":"2022030915261889600_ivab093-B2","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.jsha.2013.11.003","article-title":"Aortic valve replacement in children: options and 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