{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T13:41:32Z","timestamp":1762868492232,"version":"3.37.3"},"reference-count":24,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2021,5,21]],"date-time":"2021-05-21T00:00:00Z","timestamp":1621555200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"name":"Finnish State Research"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,10,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p\/>\n               <jats:sec>\n                  <jats:title>OBJECTIVES<\/jats:title>\n                  <jats:p>Tracheobronchial stenting has an established role in the palliation of malignant central airway obstruction (CAO). The purpose of this study is to describe the experience with self-expanding metal airway stents in 2 tertiary referral centres, covering a third of the population of Finland.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>METHODS<\/jats:title>\n                  <jats:p>Patients referred to and treated with airway stenting for malignant CAO using self-expanding metal-stents were identified from electronic patient records, and data were collected using a structured Endoscopic Lower Airway Management instrument. Statistical analysis to reveal factors affecting patient benefit and survival was carried out.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>RESULTS<\/jats:title>\n                  <jats:p>A total of 101 patients (mean age 65.8) and 116 procedures were identified. Procedure-related mortality was rare (3\/101 patients) and complications infrequent. The median survival was 2.3\u2009months [95% confidence interval (CI): 1.4\u20133.1). Stent benefit was not significantly affected by clinical characteristics. Survival was impacted by the use of adjunct procedures [hazard ratio (HR) 0.36, 95% CI: 0.23\u20130.58, P\u2009&amp;lt;\u20090.001), procedural urgency (HR 0.40; 95% CI: 0.23\u20130.71, P\u2009=\u20090.002) and post-treatment chemoradiotherapy (HR 0.29, 95% CI: 0.15\u20130.56, P\u2009&amp;lt;\u20090.001).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>CONCLUSIONS<\/jats:title>\n                  <jats:p>The beneficial impact observed supports the further use of tracheobronchial stenting in malignant CAO. The use of self-expanding metal stents is encouraged.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/icvts\/ivab147","type":"journal-article","created":{"date-parts":[[2021,4,24]],"date-time":"2021-04-24T19:10:55Z","timestamp":1619291455000},"page":"557-563","source":"Crossref","is-referenced-by-count":8,"title":["Tracheobronchial stents in patients with malignant airway disease: Finnish tertiary care experience"],"prefix":"10.1093","volume":"33","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5385-7065","authenticated-orcid":false,"given":"Johannes","family":"Routila","sequence":"first","affiliation":[{"name":"Department of Otorhinolaryngology\u2014Head and Neck Surgery, Turku University Hospital, Turku, Finland"},{"name":"Department of Otorhinolaryngology\u2014Head and Neck Surgery, University of Turku, Turku, Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eino","family":"Herhi","sequence":"additional","affiliation":[{"name":"Department of 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Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jami","family":"Rekola","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology\u2014Head and Neck Surgery, Turku University Hospital, Turku, Finland"},{"name":"Department of Otorhinolaryngology\u2014Head and Neck Surgery, University of Turku, Turku, Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2021,5,21]]},"reference":[{"key":"2022030915263095200_ivab147-B1","doi-asserted-by":"crossref","first-page":"S1087","DOI":"10.21037\/jtd.2017.07.27","article-title":"Malignant central airway obstruction","volume":"9","author":"Mudambi","year":"2017","journal-title":"J Thorac Dis"},{"key":"2022030915263095200_ivab147-B2","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1053\/j.semtcvs.2009.08.002","article-title":"Endoscopic management of central airway 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