{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T16:48:22Z","timestamp":1788281302518,"version":"build-2803163510"},"reference-count":29,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2021,7,19]],"date-time":"2021-07-19T00:00:00Z","timestamp":1626652800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,11,22]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>\u2002<\/jats:title>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>OBJECTIVES<\/jats:title>\n                  <jats:p>Practice patterns for the use of extracorporeal membrane oxygenation (ECMO) during high-risk airway interventions vary, and data are limited. We aim to characterize our recent experience using ECMO for procedural support during whole-lung lavage (WLL) and high-risk bronchoscopy for central airway obstruction (CAO).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>METHODS<\/jats:title>\n                  <jats:p>We performed a retrospective cohort study of adults who received ECMO during WLL and high-risk bronchoscopy from 1 July 2018 to 30 March 2020. Our primary end point was successful completion of the intervention. Secondary end points included ECMO-associated complications and hospital survival.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>RESULTS<\/jats:title>\n                  <jats:p>Eight patients received venovenous ECMO for respiratory support during 9 interventions; 3 WLLs for pulmonary alveolar proteinosis were performed in 2 patients, and 6 patients underwent 6 bronchoscopic interventions for CAO. We initiated ECMO prior to the intervention in 8 cases and during the intervention in 1 case for respiratory decompensation. All 9 interventions were successfully completed. Median ECMO duration was 17.8\u2009h (interquartile range, 15.9\u201326.6) for the pulmonary alveolar proteinosis group and 1.9\u2009h (interquartile range, 1.4\u20138.1) for the CAO group. There was 1 cannula-associated deep vein thrombosis; there were no other ECMO complications. Seven patients (87.5%) and 4 (50.0%) patients survived to discharge and 1 year postintervention, respectively.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>CONCLUSIONS<\/jats:title>\n                  <jats:p>Use of venovenous ECMO to facilitate high-risk airway interventions is safe and feasible. Planned preprocedural ECMO initiation may prevent avoidable respiratory emergencies and extend therapeutic airway interventions to patients otherwise considered too high-risk to treat. Guidelines are needed to inform the utilization of ECMO during high-risk bronchoscopy and other airway interventions.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/icvts\/ivab195","type":"journal-article","created":{"date-parts":[[2021,6,26]],"date-time":"2021-06-26T11:10:30Z","timestamp":1624705830000},"page":"913-920","source":"Crossref","is-referenced-by-count":19,"title":["Venovenous extracorporeal membrane oxygenation during high-risk airway interventions"],"prefix":"10.1093","volume":"33","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8776-1264","authenticated-orcid":false,"given":"John W","family":"Stokes","sequence":"first","affiliation":[{"name":"Department of Thoracic Surgery, Vanderbilt University Medical Center, Nashville, TN, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1055-4678","authenticated-orcid":false,"given":"James M","family":"Katsis","sequence":"additional","affiliation":[{"name":"Department of Pulmonary and Critical Care Medicine, Rush University Medical Center, Chicago, IL, USA"},{"name":"Department of Cardiovascular and Thoracic Surgery, Rush University, Medical Center, Chicago, IL, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Whitney D","family":"Gannon","sequence":"additional","affiliation":[{"name":"Department of Allergy, Pulmonary, and Critical Care Medicine, Vanderbilt University Medical Center, Nashville, TN, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7136-5408","authenticated-orcid":false,"given":"Todd W","family":"Rice","sequence":"additional","affiliation":[{"name":"Department of Allergy, Pulmonary, and Critical Care Medicine, Vanderbilt University Medical Center, Nashville, TN, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8186-0832","authenticated-orcid":false,"given":"Robert 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USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clayne","family":"Benson","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, Vanderbilt University Medical Center, Nashville, TN, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4456-4484","authenticated-orcid":false,"given":"Matthew","family":"Bacchetta","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, Vanderbilt University Medical Center, Nashville, TN, USA"},{"name":"Department of Cardiac Surgery, Vanderbilt University Medical Center, Nashville, TN, USA"},{"name":"Department of Biomedical Engineering, Vanderbilt University Medical Center, Nashville, TN, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6504-2063","authenticated-orcid":false,"given":"Fabien","family":"Maldonado","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, 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