{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T22:29:27Z","timestamp":1792794567296,"version":"4.5.0"},"reference-count":30,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2021,8,27]],"date-time":"2021-08-27T00:00:00Z","timestamp":1630022400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Skane Regional Research Fund, ALF-funds"},{"name":"University of Iceland Research Fund","id":[{"id":"https:\/\/ror.org\/01db6h964","id-type":"ROR","asserted-by":"crossref"}]},{"name":"Landspitali Research Fund and the Mats Kleberg Foundation"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,1,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>\u2002<\/jats:title>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>OBJECTIVES<\/jats:title>\n                    <jats:p>Acute type A aortic dissection (ATAAD) is a rare but severe condition, routinely treated with emergent cardiac surgery. Many surgeons have the notion that patients with ATAAD tend to come in clusters, but no studies have examined these observations. This investigation was undertaken to study the potential association between the lunar cycle and the incidence of ATAAD.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS<\/jats:title>\n                    <jats:p>We collected information on 2995 patients who underwent ATAAD surgery at centres from the Nordic Consortium for Acute Type A Aortic Dissection collaboration. We cross-referenced the time of surgery with lunar phase using a case-crossover design with 2 different definitions of full moon (&amp;gt;99% illumination and the 7-day full moon period).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS<\/jats:title>\n                    <jats:p>The period when the moon was illuminated the most (99% definition) did not show any significant increase in incidence for ATAAD surgery. However, when the full moon period was compared with all other moon phases, it yielded a relative risk of 1.08 [95% confidence interval (CI) 1.00\u20131.17, P\u2009=\u20090.057] and, compared to waxing moon, only the relative risk was 1.11 (95% CI 1.01\u20131.23, P\u2009=\u20090.027). The peak incidence came 4\u20136\u2009days after the moon was fully illuminated.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSIONS<\/jats:title>\n                    <jats:p>This study found an overrepresentation of surgery for ATAAD during the full moon phase. The explanation for this is not known, but we speculate that sleep deprivation during full moon leads to a temporary increase in blood pressure, which in turn could trigger rupture of the aortic wall. While this finding is interesting, it needs to be corroborated and the clinical implications are debateable.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/icvts\/ivab220","type":"journal-article","created":{"date-parts":[[2021,8,27]],"date-time":"2021-08-27T18:41:55Z","timestamp":1630089715000},"page":"105-110","source":"Crossref","is-referenced-by-count":9,"title":["Once after a full moon: acute type A aortic dissection and lunar phases"],"prefix":"10.1093","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5428-7455","authenticated-orcid":false,"given":"Henrik","family":"Bjursten","sequence":"first","affiliation":[{"name":"Department of Cardiothoracic Surgery, Lund University, Sk\u00e5ne University Hospital, Lund, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Oudin \u00c5str\u00f6m","sequence":"additional","affiliation":[{"name":"Division of Occupational and Environmental Medicine, Department of Laboratory Medicine, Lund University, Lund, Sweden"},{"name":"Division of Sustainable Health, Department of Public Health and Clinical Medicine, Ume\u00e5 University, Ume\u00e5, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shahab","family":"Nozohoor","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, Lund University, Sk\u00e5ne University Hospital, Lund, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Khalil","family":"Ahmad","sequence":"additional","affiliation":[{"name":"Department of Thoracic and Cardiovascular Surgery, Aarhus University Hospital, Skejby, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariann","family":"Tang","sequence":"additional","affiliation":[{"name":"Department of Thoracic and Cardiovascular Surgery, Aarhus University Hospital, Skejby, 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