{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,16]],"date-time":"2026-02-16T17:19:52Z","timestamp":1771262392130,"version":"3.50.1"},"reference-count":5,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2021,11,24]],"date-time":"2021-11-24T00:00:00Z","timestamp":1637712000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,2,21]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Myasthenia gravis (MG) is an autoimmune neuromuscular junction disorder and rarely coexists with aortic aneurysms requiring open repair. A 66-year-old patient with MG underwent extended thoraco-abdominal aortic aneurysm (TAAA) repair 16\u2009years after onset of type-B acute aortic dissection. At 62\u2009years, the patient was diagnosed with MG (MGFA class IIIa) from positive anti-acetylcholine receptor antibody without thymoma. Preoperatively, MG was well-controlled by prednisolone, cyclosporin and pyridostigmine. Extent II TAAA repair was performed under general anaesthesia maintained by total intravenous anaesthesia. Transcranial motor-evoked potential and somatosensory-evoked potential were applied to monitor intraoperative spinal cord ischaemia and muscle weakness. Amplitudes of motor-evoked potential and somatosensory-evoked potential attenuated intraoperatively but normalized after reperfusion from the reconstructed tube graft. Perioperative steroid coverage was given against surgical stress. The patient was weaned from mechanical ventilatory support on postoperative day 7. No signs of spinal cord ischaemia or muscle weakness were seen.<\/jats:p>","DOI":"10.1093\/icvts\/ivab331","type":"journal-article","created":{"date-parts":[[2021,11,9]],"date-time":"2021-11-09T12:13:23Z","timestamp":1636460003000},"page":"510-511","source":"Crossref","is-referenced-by-count":3,"title":["Open thoracoabdominal aortic aneurysm repair in a patient with myasthenia gravis"],"prefix":"10.1093","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6411-1856","authenticated-orcid":false,"given":"Kyokun","family":"Uehara","sequence":"first","affiliation":[{"name":"Department of Cardiovascular Surgery, Tenri Hospital, Nara, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasue","family":"Fujiwara","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Tenri Hospital, Nara, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manabu","family":"Morishima","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Tenri Hospital, Nara, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Atsushi","family":"Iwakura","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Tenri Hospital, Nara, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2021,11,24]]},"reference":[{"key":"2022022119395479800_ivab331-B1","first-page":"139","article-title":"Stanford type A acute aortic dissection with myasthenia gravis: report of a case","volume":"74","author":"Inoue","year":"2021","journal-title":"Kyobu Geka"},{"key":"2022022119395479800_ivab331-B2","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1111\/j.1540-8191.2008.00693.x","article-title":"Successful mitral valve surgery in a patient with myasthenia gravis","volume":"24","author":"Narin","year":"2009","journal-title":"J Card Surg"},{"key":"2022022119395479800_ivab331-B3","doi-asserted-by":"crossref","first-page":"209","DOI":"10.4103\/aca.ACA_176_18","article-title":"Anaesthetic management of myasthenia gravis in coronary artery bypass grafting","volume":"23","author":"Vanjari","year":"2020","journal-title":"Ann Card Anaesth"},{"key":"2022022119395479800_ivab331-B4","first-page":"3278147","article-title":"Anesthetic management of total aortic arch replacement in a myasthenia gravis patient under deep hypothermic circulatory arrest","volume":"2019","author":"Kondo","year":"2019","journal-title":"Case Rep Anesthesiol"},{"key":"2022022119395479800_ivab331-B5","first-page":"485","article-title":"Anesthesia and perioperative considerations for patients with myasthenia gravis","volume":"88","author":"Collins","year":"2020","journal-title":"AANA J"}],"container-title":["Interactive CardioVascular and Thoracic Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/icvts\/article-pdf\/34\/3\/510\/42571246\/ivab331.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/icvts\/article-pdf\/34\/3\/510\/42571246\/ivab331.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,2,21]],"date-time":"2022-02-21T19:42:03Z","timestamp":1645472523000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/icvts\/article\/34\/3\/510\/6438134"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,11,24]]},"references-count":5,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2021,11,24]]},"published-print":{"date-parts":[[2022,2,21]]}},"URL":"https:\/\/doi.org\/10.1093\/icvts\/ivab331","relation":{},"ISSN":["1569-9285"],"issn-type":[{"value":"1569-9285","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2022,3,1]]},"published":{"date-parts":[[2021,11,24]]}}}