{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,25]],"date-time":"2025-11-25T20:40:50Z","timestamp":1764103250744,"version":"3.37.3"},"reference-count":29,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2021,12,6]],"date-time":"2021-12-06T00:00:00Z","timestamp":1638748800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,2,21]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>\u2002<\/jats:title>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>OBJECTIVES<\/jats:title>\n                  <jats:p>To report our experience on the management of superior vena cava graft infection.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>METHODS<\/jats:title>\n                  <jats:p>Between 2001 and 2018, patients with superior vena cava synthetic graft or patch reconstruction after resection of intrathoracic tumours or benign disease were selected retrospectively from the French EPITHOR database and participating thoracic centres. Our study population includes patients with superior vena cava graft infection, defined according to the MAGIC consensus. Superior vena cava synthetic grafts in an empyema or mediastinitis were considered as infected.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>RESULTS<\/jats:title>\n                  <jats:p>Of 111 eligible patients, superior vena cava graft infection occurred in 12 (11.9%) patients with a polytetrafluoroethylene graft secondary to contiguous contamination. Management consisted of either conservative treatment with chest tube drainage and antibiotics (n\u2009=\u20093) or a surgical graft-sparing strategy (n\u2009=\u20099). Recurrence of infection appears in 6 patients. Graft removal was performed in 2 patients among the 5 reoperated patients. The operative mortality rate was 25%.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>CONCLUSIONS<\/jats:title>\n                  <jats:p>Superior vena cava graft infection may develop as a surgical site infection secondary to early mediastinitis or empyema. Graft removal is not always mandatory but should be considered in late or recurrent graft infection or in infections caused by aggressive microorganisms (virulent or multidrug resistant bacteria or fungi).<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/icvts\/ivab337","type":"journal-article","created":{"date-parts":[[2021,11,10]],"date-time":"2021-11-10T20:37:21Z","timestamp":1636576641000},"page":"378-385","source":"Crossref","is-referenced-by-count":1,"title":["Superior vena cava graft infection in thoracic surgery: a retrospective study of the French EPITHOR database"],"prefix":"10.1093","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1433-9390","authenticated-orcid":false,"given":"Laura","family":"Filaire","sequence":"first","affiliation":[{"name":"Department of Thoracic and Endocrine Surgery, Jean Perrin Comprehensive Cancer Centre, Clermont-Ferrand, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Olaf","family":"Mercier","sequence":"additional","affiliation":[{"name":"Department of Thoracic and Vascular Surgery and Heart and Lung Transplantation, H\u00f4pital Marie Lannelongue, Paris, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2906-4433","authenticated-orcid":false,"given":"Agathe","family":"Seguin-Givelet","sequence":"additional","affiliation":[{"name":"Thoracic Department, Curie-Montsouris Thorax Institute, Paris, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Olivier","family":"Tiffet","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, North Hospital, Saint-\u00c9tienne, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pierre Emmanuel","family":"Falcoz","sequence":"additional","affiliation":[{"name":"Thoracic Surgery Department, Nouvel H\u00f4pital Civil, Strasbourg, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pierre","family":"Mordant","sequence":"additional","affiliation":[{"name":"Division of Thoracic and Vascular Surgery, H\u00f4pital Bichat, Paris, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pierre-Yves","family":"Brichon","sequence":"additional","affiliation":[{"name":"Department of Thoracic and Endocrine Surgery, University Hospital of Grenoble, Grenoble, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Philippe","family":"Lacoste","sequence":"additional","affiliation":[{"name":"Department of Thoracic and Cardiovascular Surgery, Nantes Hospital University, Nantes, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Axel","family":"Aubert","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, Clinique Belledone, Grenoble, 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