{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T12:02:55Z","timestamp":1753876975805,"version":"3.41.2"},"reference-count":25,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2022,5,6]],"date-time":"2022-05-06T00:00:00Z","timestamp":1651795200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,8,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p\/>\n               <jats:sec>\n                  <jats:title>OBJECTIVES<\/jats:title>\n                  <jats:p>The paediatric tracheobronchial inflammatory myofibroblastic tumour (IMT) is a rare disease. Whether limited surgical resection is a feasible surgical approach for these patients remains controversial. The objectives of this study were to report the long-term prognosis after limited surgical resections on paediatric tracheobronchial IMT and provide a surgical management strategy for this rare disease.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>METHODS<\/jats:title>\n                  <jats:p>Paediatric tracheobronchial IMT patients who underwent limited surgical resection from 2012 to 2020 were enrolled in this study. The clinical characteristics, course of treatment and long-term outcomes of all participants were collated. We presented the accumulated data and analysed the feasibility of limited surgical resection on the paediatric tracheobronchial IMT.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>RESULTS<\/jats:title>\n                  <jats:p>A total of 9 children with tracheobronchial IMTs were enrolled in our study. Cough and shortness of breath were the most common symptoms. All 9 participants underwent surgical treatment, including 2 tracheal reconstructions, 4 carinal reconstructions and 3 bronchial sleeve resections. Among the participants, 6\/9 (66%) were positive for the anaplastic lymphoma receptor tyrosine kinase gene in terms of immunohistochemistry. None of the participants died of short-term complications. The follow-up period was 5.4 (range, 1.1\u20139.3) years, during which all participants remained well.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>CONCLUSIONS<\/jats:title>\n                  <jats:p>Limited surgical resection is preferred for paediatrics with tracheobronchial IMTs. Meanwhile, patients with complete resection have an excellent long-term prognosis.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/icvts\/ivac117","type":"journal-article","created":{"date-parts":[[2022,5,4]],"date-time":"2022-05-04T19:10:05Z","timestamp":1651691405000},"source":"Crossref","is-referenced-by-count":1,"title":["Limited airway resection and reconstruction for paediatric tracheobronchial inflammatory myofibroblastic tumour"],"prefix":"10.1093","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1558-1349","authenticated-orcid":false,"given":"Junguo","family":"Dong","sequence":"first","affiliation":[{"name":"Department of Thoracic Surgery and Oncology, the First Affiliated Hospital of Guangzhou Medical University, State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health , Guangzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Diego","family":"Gonzalez-Rivas","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, Coru\u00f1a University Hospital , Coru\u00f1a, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pengcheng","family":"Lv","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery and Oncology, the First Affiliated Hospital of Guangzhou Medical University, State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health , Guangzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhexin","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, Shanghai Chest Hospital, Shanghai Jiao Tong University , Shanghai, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiaxi","family":"He","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery and Oncology, the First Affiliated Hospital of Guangzhou Medical University, State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health , Guangzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Feng","family":"Yao","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, Shanghai Chest Hospital, Shanghai Jiao Tong University , Shanghai, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shuben","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery and Oncology, the First Affiliated Hospital of Guangzhou Medical University, State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health , Guangzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2022,5,6]]},"reference":[{"key":"2022082714182742600_ivac117-B1","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1016\/j.jpedsurg.2015.11.015","article-title":"Inflammatory myofibroblastic tumors in children","volume":"51","author":"Dalton","year":"2016","journal-title":"J Pediatr Surg"},{"key":"2022082714182742600_ivac117-B2","first-page":"171","article-title":"Pediatric inflammatory myofibroblastic tumors of the airway: two case reports with varying clinical presentation","volume":"30","author":"Kumar","year":"2018","journal-title":"Iran J Otorhinolaryngol"},{"key":"2022082714182742600_ivac117-B3","first-page":"S68","article-title":"Manual trans-tracheal high frequency positive pressure ventilation for left main bronchus and carinal mass surgical resection in a child","volume":"27","author":"Akhtar","year":"2017","journal-title":"J Coll Physicians Surg Pak"},{"key":"2022082714182742600_ivac117-B4","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/S0096-5588(20)30758-3","article-title":"Postinflammatory tumors of the lung; 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