{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,21]],"date-time":"2026-02-21T03:56:10Z","timestamp":1771646170671,"version":"3.50.1"},"reference-count":28,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2022,5,30]],"date-time":"2022-05-30T00:00:00Z","timestamp":1653868800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,7,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>OBJECTIVES<\/jats:title>\n                  <jats:p>The aim of this study was to determine the long-term results of mitral valve (MV) repair with anterior leaflet patch augmentation.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>METHODS<\/jats:title>\n                  <jats:p>Between 2012 and 2015, 45 patients underwent MV repair using the anterior leaflet patch augmentation technique at our institution. The mean age of the patients was 65.9\u2009\u00b1\u200913.0\u2009years (16 males). We reviewed the MV pathology and the surgical techniques used and assessed the early and late results.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>RESULTS<\/jats:title>\n                  <jats:p>In terms of MV pathology, 43 patients (95.6%) had pure mitral regurgitation (MR) and 2 patients (4.4%) had mixed mitral stenosis and MR. Rheumatic changes were seen in 18 patients (40.0%). Postoperative echocardiography showed that 95.6% of patients had none to mild MR. During a median follow-up period of 5.5\u2009years (range 0.1\u20138.3\u2009years), there were 8 late deaths. Nine patients (20%) required reoperation. The mean interval between the initial operation and redo operation was 3.7\u2009\u00b1\u20093.1\u2009years (range: 0.4\u20137.8\u2009years). The causes of reoperation included patch dehiscence (n\u2009=\u20094), progression of mitral stenosis (n\u2009=\u20092), band dehiscence (n\u2009=\u20091), patch enlargement (n\u2009=\u20091) and unknown (n\u2009=\u20091). Eight patients underwent MV replacement and 1 underwent repeat MV repair. The freedom from reoperation at 3 and 5\u2009years was 85.7\u2009\u00b1\u20096.7% and 81.2\u2009\u00b1\u20097.7%, respectively.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>CONCLUSIONS<\/jats:title>\n                  <jats:p>Anterior leaflet patch augmentation can provide excellent early results in the majority of the patients even in the presence of rheumatic pathology; however, we observed late reoperation in 20% of patients. Thus, this technique should be used with caution and careful follow-up with serial echocardiography is essential.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/icvts\/ivac144","type":"journal-article","created":{"date-parts":[[2022,5,31]],"date-time":"2022-05-31T22:17:01Z","timestamp":1654035421000},"source":"Crossref","is-referenced-by-count":4,"title":["Early and late results of mitral valve repair with anterior leaflet patch augmentation"],"prefix":"10.1093","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1411-1062","authenticated-orcid":false,"given":"Hiromu","family":"Kehara","sequence":"first","affiliation":[{"name":"Division of Cardiovascular Surgery, Temple University and Lewis Katz School of Medicine , Philadelphia, PA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4487-8224","authenticated-orcid":false,"given":"Kenji","family":"Minakata","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Surgery, Temple University and Lewis Katz School of Medicine , Philadelphia, PA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James","family":"McCarthy","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Surgery, Temple University and Lewis Katz School of Medicine , Philadelphia, PA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gengo","family":"Sunagawa","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Surgery, Temple University and Lewis Katz School of Medicine , Philadelphia, PA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7950-2238","authenticated-orcid":false,"given":"Chirantan","family":"Mangukia","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Surgery, Temple University and Lewis Katz School of Medicine , Philadelphia, PA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stacey","family":"Brann","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Surgery, Temple University and Lewis Katz School of Medicine , Philadelphia, PA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huaqing","family":"Zhao","sequence":"additional","affiliation":[{"name":"Center for Biostatistics and Epidemiology, Department of Biomedical Education and Data Science, Temple University and Lewis Katz School of Medicine , Philadelphia, PA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert","family":"Boova","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Surgery, Temple University and Lewis Katz School of Medicine , Philadelphia, PA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshiya","family":"Toyoda","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Surgery, Temple University and Lewis Katz School of Medicine , Philadelphia, PA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2022,5,30]]},"reference":[{"key":"2022072011060050200_ivac144-B1","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1016\/j.pcad.2017.10.006","article-title":"Mitral valve repair in degenerative mitral regurgitation: state of the art","volume":"60","author":"Bonis","year":"2017","journal-title":"Prog Cardiovasc Dis"},{"key":"2022072011060050200_ivac144-B2","doi-asserted-by":"crossref","first-page":"1990","DOI":"10.1016\/j.athoracsur.2020.04.031","article-title":"Does referral bias impact outcomes of surgery for degenerative mitral valve disease?","volume":"110","author":"Hasan","year":"2020","journal-title":"Ann Thorac Surg"},{"key":"2022072011060050200_ivac144-B3","doi-asserted-by":"crossref","DOI":"10.1016\/j.jtcvs.2020.09.129","article-title":"A multiparameter algorithm to guide repair of degenerative mitral regurgitation","author":"McCarthy","year":"2020","journal-title":"J Thorac Cardiovasc Surg"},{"key":"2022072011060050200_ivac144-B4","doi-asserted-by":"crossref","first-page":"1022","DOI":"10.1161\/01.CIR.91.4.1022","article-title":"Valve repair improves the outcome of surgery for mitral regurgitation. 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