{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T12:01:56Z","timestamp":1753876916211,"version":"3.41.2"},"reference-count":4,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2022,9,2]],"date-time":"2022-09-02T00:00:00Z","timestamp":1662076800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,9,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Tumours or tumour-like lesions around the aortic valve are relatively rare and are difficult to diagnose. We report an interesting case of calcified thrombi in the Valsalva sinuses and coronary cusps that mimicked an aortic valve tumour. A 68-year-old man presented with a 20-mm calcified mass in the non-coronary and left-coronary cusps extending to their corresponding Valsalva sinuses, which was detected by echocardiography and contrast-enhanced computed tomography. The lesions were resected to establish the diagnosis and prevent systemic embolization. Intraoperative and histopathological examination revealed an atrophied non-coronary leaflet and calcified atherosclerotic lesions of the Valsalva sinuses and contiguous parts of the cusps, with ulceration and fibrin thrombi. The lesions were resected and aortic valve replacement was performed to avoid aortic valve dysfunction. The patient\u2019s atrial fibrillation was controlled, and anticoagulants were discontinued 3 months postoperatively. Surgery to establish the diagnosis and to prevent systemic thromboembolism was thought to be reasonable, even in the absence of valvular dysfunction.<\/jats:p>","DOI":"10.1093\/icvts\/ivac232","type":"journal-article","created":{"date-parts":[[2022,8,31]],"date-time":"2022-08-31T20:18:28Z","timestamp":1661977108000},"source":"Crossref","is-referenced-by-count":0,"title":["Calcified thrombi of the Valsalva sinuses mimicking an aortic valve tumour"],"prefix":"10.1093","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2531-4885","authenticated-orcid":false,"given":"Ryo","family":"Nakamura","sequence":"first","affiliation":[{"name":"Department of Thoracic and Cardiovascular Surgery, Wakayama Medical University Hospital , Wakayama City, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7151-6480","authenticated-orcid":false,"given":"Kentaro","family":"Honda","sequence":"additional","affiliation":[{"name":"Department of Thoracic and Cardiovascular Surgery, Wakayama Medical University Hospital , Wakayama City, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8084-6983","authenticated-orcid":false,"given":"Hideki","family":"Kunimoto","sequence":"additional","affiliation":[{"name":"Department of Thoracic and Cardiovascular Surgery, Wakayama Medical University Hospital , Wakayama City, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0074-4523","authenticated-orcid":false,"given":"Yoshiharu","family":"Nishimura","sequence":"additional","affiliation":[{"name":"Department of Thoracic and Cardiovascular Surgery, Wakayama Medical University Hospital , Wakayama City, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2022,9,2]]},"reference":[{"key":"2022092118384464300_ivac232-B1","doi-asserted-by":"crossref","first-page":"e161","DOI":"10.1016\/j.jtcvs.2019.04.094","article-title":"Calcified amorphous tumor in the aortic valve identified by computed tomography","volume":"159","author":"Koyama","year":"2020","journal-title":"J Thorac Cardiovasc Surg"},{"key":"2022092118384464300_ivac232-B2","doi-asserted-by":"crossref","first-page":"e235","DOI":"10.1016\/j.athoracsur.2018.01.050","article-title":"A calcified amorphous tumor originating in the aortic valve cusp","volume":"105","author":"Kasai","year":"2018","journal-title":"Ann Thorac Surg"},{"key":"2022092118384464300_ivac232-B3","doi-asserted-by":"crossref","first-page":"148","DOI":"10.4250\/jcu.2014.22.3.148","article-title":"Native aortic valve thrombosis resembling papillary fibroelastoma","volume":"22","author":"Kim","year":"2014","journal-title":"J Cardiovasc Ultrasound"},{"key":"2022092118384464300_ivac232-B4","doi-asserted-by":"crossref","first-page":"e35","DOI":"10.4081\/rt.2009.e35","article-title":"Tumors and tumor-like lesions of the heart valves","volume":"1","author":"Yuan","year":"2009","journal-title":"Rare Tumors"}],"container-title":["Interactive CardioVascular and Thoracic Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/icvts\/advance-article-pdf\/doi\/10.1093\/icvts\/ivac232\/45666146\/ivac232.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/icvts\/article-pdf\/35\/4\/ivac232\/45947506\/ivac232.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/icvts\/article-pdf\/35\/4\/ivac232\/45947506\/ivac232.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,9,21]],"date-time":"2022-09-21T18:41:27Z","timestamp":1663785687000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/icvts\/article\/doi\/10.1093\/icvts\/ivac232\/6687130"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,9,2]]},"references-count":4,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2022,9,9]]}},"URL":"https:\/\/doi.org\/10.1093\/icvts\/ivac232","relation":{},"ISSN":["1569-9285"],"issn-type":[{"type":"electronic","value":"1569-9285"}],"subject":[],"published-other":{"date-parts":[[2022,10,1]]},"published":{"date-parts":[[2022,9,2]]},"article-number":"ivac232"}}