{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T02:54:21Z","timestamp":1761706461090,"version":"3.41.2"},"reference-count":22,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2022,11,7]],"date-time":"2022-11-07T00:00:00Z","timestamp":1667779200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2022,11,7]],"date-time":"2022-11-07T00:00:00Z","timestamp":1667779200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,3,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p\/>\n               <jats:sec>\n                  <jats:title>Objective<\/jats:title>\n                  <jats:p>The goal was to report the midterm performance of decellularized equine pericardium used for repair of various congenital heart defects in the paediatric population.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>A retrospective review of all patients undergoing patch implants between 2016 and 2020 was performed. Patch quality, surgical handling, haemostasis and early patch-related complications were studied in all patients. Midterm performance was observed in patients with \u226512 months follow-up and an intact patch at discharge (without reoperation\/stent implant).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>A total of 201 patients with a median age of 2.5 years [interquartile range: 0.6-6.5] underwent 207 procedures at 314 implant locations. The patch was used in the following numbers\/locations: 171 for pulmonary artery (PA) augmentation, 36 for aortic repair, 35 for septal defect closure, 22 for valvular repair and 50 at other locations. Early\/30-day mortality was 6.5%. Early patch-related reoperations\/stent implants occurred in 28 locations (8.9%). No patch-related complications were noted except for bleeding in 3 locations (1%). Follow-up for \u2265 12 months was available for 132 patients\/200 locations. During a median follow-up of 29.7 months [interquartile range: 20.7-38.3], 53 patch-related reoperations\/catheter reinterventions occurred (26.5%), with the majority in the PA position (88.7%, 47\/53). Overall 12- and 24-months freedom from patch-related reoperation\/catheter reintervention per location was 91.5% (95% confidence interval: 86.7%-94.6%) and 85.2% (95% confidence interval: 78.9%-89.6%), respectively.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>Decellularized equine pericardium used for repair of various congenital heart defects showed acceptable midterm performance. The range of reoperation\/reintervention rates was similar to those observed with other xenogeneic materials in previously reported articles, occurring most frequently after PA augmentation.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/icvts\/ivac269","type":"journal-article","created":{"date-parts":[[2022,11,7]],"date-time":"2022-11-07T13:17:28Z","timestamp":1667827048000},"source":"Crossref","is-referenced-by-count":5,"title":["Midterm performance of decellularized equine pericardium in congenital heart surgery"],"prefix":"10.1093","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0153-0364","authenticated-orcid":false,"given":"Viktoria H M","family":"Weixler","sequence":"first","affiliation":[{"name":"Department of Congenital Heart Surgery - Pediatric Heart Surgery, German Heart Center Berlin , Berlin, Germany"},{"name":"DZHK (German Centre for Cardiovascular Research) , partner site Berlin, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kira","family":"Kuschnerus","sequence":"additional","affiliation":[{"name":"Department of Congenital Heart Surgery - Pediatric Heart Surgery, German Heart Center Berlin , Berlin, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Olga","family":"Romanchenko","sequence":"additional","affiliation":[{"name":"Department of Congenital Heart Surgery - Pediatric Heart Surgery, German Heart Center Berlin , Berlin, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7999-6880","authenticated-orcid":false,"given":"Stanislav","family":"Ovroutski","sequence":"additional","affiliation":[{"name":"Department of Congenital Heart Disease - Pediatric Cardiology, German Heart Center Berlin , Berlin, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mi-Young","family":"Cho","sequence":"additional","affiliation":[{"name":"Department of Congenital Heart Surgery - Pediatric Heart Surgery, German Heart Center Berlin , Berlin, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Felix","family":"Berger","sequence":"additional","affiliation":[{"name":"DZHK (German Centre for Cardiovascular Research) , partner site Berlin, Germany"},{"name":"Department of Congenital Heart Disease - Pediatric Cardiology, German Heart Center Berlin , Berlin, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4110-7694","authenticated-orcid":false,"given":"Matthias","family":"Sigler","sequence":"additional","affiliation":[{"name":"Department of Pediatric Cardiology and Intensive Care Medicine, Georg-August University G\u00f6ttingen , G\u00f6ttingen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9207-8010","authenticated-orcid":false,"given":"Nicod\u00e8me","family":"Sinzobahamvya","sequence":"additional","affiliation":[{"name":"Department of Congenital Heart Surgery - Pediatric Heart Surgery, German Heart Center Berlin , Berlin, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3140-9154","authenticated-orcid":false,"given":"Joachim","family":"Photiadis","sequence":"additional","affiliation":[{"name":"Department of Congenital Heart Surgery - Pediatric Heart Surgery, German Heart Center Berlin , Berlin, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6477-5727","authenticated-orcid":false,"given":"Peter","family":"Murin","sequence":"additional","affiliation":[{"name":"Department of Congenital Heart Surgery - Pediatric Heart Surgery, German Heart Center Berlin , Berlin, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2022,11,7]]},"reference":[{"issue":"3","key":"2024061610011688400_ivac269-B1","doi-asserted-by":"crossref","first-page":"202","DOI":"10.14503\/THIJ-14-4296","article-title":"Is autologous or heterologous pericardium better for valvuloplasty? 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