{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,20]],"date-time":"2025-08-20T12:48:22Z","timestamp":1755694102119,"version":"3.41.2"},"reference-count":14,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2023,7,24]],"date-time":"2023-07-24T00:00:00Z","timestamp":1690156800000},"content-version":"vor","delay-in-days":23,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,7,19]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p\/>\n               <jats:sec>\n                  <jats:title>OBJECTIVES<\/jats:title>\n                  <jats:p>There are several surgical approaches for explanting a left ventricular assist device (LVAD) after recovery of cardiac function. Thus, remaining ventricular assist device components may bear significant risks of infection or thrombosis. We hereby report our technique and two-center experience with explantation of LVADs using a new double-patch technique.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>METHODS<\/jats:title>\n                  <jats:p>From March 2019 to April 2021, five patients underwent LVAD explantation after myocardial recovery (HVAD, n\u2009=\u20092; HeartMate 3, n\u2009=\u20093). The mean patient age was 50.3\u2009years (100% male); the mean time on the LVAD was 23.1\u2009\u00b1\u200920.8\u2009months. The aetiology of the primary heart failure was dilated cardiomyopathy (n\u2009=\u20094) and myocarditis (n\u2009=\u20091).<\/jats:p>\n                  <jats:p>LVAD explantation was performed using a median sternotomy and cardiopulmonary bypass. The LVAD was stopped, and the outflow graft was clamped. The outflow graft was ligated and sutured close to the aortic anastomosis. The driveline was clipped and removed. Under induced fibrillation, the attachment of the LVAD was released from the apical cuff and the LVAD was removed. A round pericardial patch was fixed from the inner of the ventricle. This step sealed the apex of the heart. An additional Gore-Tex patch was continuously sutured epicardially over the suture ring.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>RESULTS<\/jats:title>\n                  <jats:p>The 5 cases showed technically uncomplicated explantation of the LVADs. During the follow-up of a mean of 16.4\u2009\u00b1\u200916.9\u2009months, we observed 100% survival. There were no bleeding complications or thromboembolic events during the follow-up period.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>CONCLUSIONS<\/jats:title>\n                  <jats:p>LVAD explantation with the double-patch technique is feasible and safe. This technique allows discontinuation of anticoagulation. The 30-day survival was 100%. Further studies are needed to provide better evidence for LVAD explantation and long-term follow-up.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/icvts\/ivad110","type":"journal-article","created":{"date-parts":[[2023,7,24]],"date-time":"2023-07-24T14:17:17Z","timestamp":1690208237000},"source":"Crossref","is-referenced-by-count":1,"title":["Left ventricular assist device explantation using a new double-patch technique"],"prefix":"10.1093","volume":"37","author":[{"given":"Oliver Daniel","family":"Bhadra","sequence":"first","affiliation":[{"name":"University Heart & Vascular Center Hamburg, Department for Cardiovascular Surgery , Hamburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7418-1815","authenticated-orcid":false,"given":"Jonas","family":"Pausch","sequence":"additional","affiliation":[{"name":"University Heart & Vascular Center Hamburg, Department for Cardiovascular Surgery , Hamburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9289-8927","authenticated-orcid":false,"given":"Hug","family":"Aubin","sequence":"additional","affiliation":[{"name":"Heinrich Heine University Duesseldorf, Department for Cardiovascular Surgery , Duesseldorf, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Payam","family":"Akhyari","sequence":"additional","affiliation":[{"name":"RWTH Aachen University, Department for Cardiovascular Surgery , Aachen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8580-6369","authenticated-orcid":false,"given":"Artur","family":"Lichtenberg","sequence":"additional","affiliation":[{"name":"Heinrich Heine University Duesseldorf, Department for Cardiovascular Surgery , Duesseldorf, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Markus Johannes","family":"Barten","sequence":"additional","affiliation":[{"name":"University Heart & Vascular Center Hamburg, Department for Cardiovascular Surgery , Hamburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yousuf","family":"Alassar","sequence":"additional","affiliation":[{"name":"University Heart & Vascular Center Hamburg, Department for Cardiovascular Surgery , Hamburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hermann","family":"Reichenspurner","sequence":"additional","affiliation":[{"name":"University Heart & Vascular Center Hamburg, Department for Cardiovascular Surgery , Hamburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexander Markus","family":"Bernhardt","sequence":"additional","affiliation":[{"name":"University Heart & Vascular Center Hamburg, Department for Cardiovascular Surgery , Hamburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2023,7,24]]},"reference":[{"key":"2023072623092289500_ivad110-B1","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1016\/S0003-4975(99)00042-9","article-title":"The REMATCH trial: rationale, design, and end points. Randomized Evaluation of Mechanical Assistance for the Treatment of Congestive Heart Failure","volume":"67","author":"Rose","year":"1999","journal-title":"Ann Thorac Surg"},{"key":"2023072623092289500_ivad110-B2","doi-asserted-by":"crossref","first-page":"885","DOI":"10.1056\/NEJMoa067758","article-title":"Use of a continuous-flow device in patients awaiting heart transplantation","volume":"357","author":"Miller","year":"2007","journal-title":"N Engl J Med"},{"key":"2023072623092289500_ivad110-B3","doi-asserted-by":"crossref","first-page":"2241","DOI":"10.1056\/NEJMoa0909938","article-title":"Advanced heart failure treated with continuous-flow left ventricular assist device","volume":"361","author":"Slaughter","year":"2009","journal-title":"N Engl J Med"},{"key":"2023072623092289500_ivad110-B4","doi-asserted-by":"crossref","first-page":"1540","DOI":"10.1016\/j.jacc.2016.07.743","article-title":"Cardiac Recovery During Long-Term Left Ventricular Assist Device Support","volume":"68","author":"Wever-Pinzon","year":"2016","journal-title":"J Am Coll Cardiol United States"},{"key":"2023072623092289500_ivad110-B5","doi-asserted-by":"crossref","first-page":"672","DOI":"10.1016\/j.healun.2010.01.007","article-title":"Cardiac fibrosis and cellular hypertrophy decrease the degree of reverse remodeling and improvement in cardiac function during left ventricular assist","volume":"29","author":"Saito","year":"2010","journal-title":"J Hear Lung Transplant Off Publ Int Soc Hear Transplant United States"},{"key":"2023072623092289500_ivad110-B6","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1016\/j.healun.2010.01.010","article-title":"Reversal of impaired myocardial beta-adrenergic receptor signaling by continuous-flow left ventricular assist device support","volume":"29","author":"Akhter","year":"2010","journal-title":"J Heart Lung Transplant"},{"key":"2023072623092289500_ivad110-B7","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1016\/j.jacc.2010.11.010","article-title":"Clinical, molecular, and genomic changes in response to a left ventricular assist device","volume":"57","author":"Hall","year":"2011","journal-title":"J Am Coll Cardiol"},{"key":"2023072623092289500_ivad110-B8","doi-asserted-by":"crossref","first-page":"2022","DOI":"10.3390\/jcm11072022","article-title":"The History of Durable Left Ventricular Assist Devices and Comparison of Outcomes: heartWare, HeartMate II, HeartMate 3, and the Future of Mechanical Circulatory Support","volume":"11","author":"Berardi","year":"2022","journal-title":"JCM"},{"key":"2023072623092289500_ivad110-B9","doi-asserted-by":"crossref","first-page":"1560","DOI":"10.1016\/j.healun.2021.08.001","article-title":"LVAD decommissioning for myocardial recovery: long-term ventricular remodeling and adverse events","volume":"40","author":"Gerhard","year":"2021","journal-title":"J Heart Lung Transplant"},{"key":"2023072623092289500_ivad110-B10","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1093\/icvts\/ivab344","article-title":"Results from a multicentre evaluation of plug use for left ventricular assist device explantation","volume":"34","author":"Potapov","year":"2021","journal-title":"Interact CardioVasc Thorac Surg"},{"key":"2023072623092289500_ivad110-B11","doi-asserted-by":"crossref","first-page":"822","DOI":"10.1097\/MAT.0000000000001574","article-title":"Left Ventricular Assist Device as a Bridge to Recovery: single Center Experience of Successful Device Explantation","volume":"68","author":"Zhang","year":"2022","journal-title":"Asaio J"},{"key":"2023072623092289500_ivad110-B12","doi-asserted-by":"crossref","first-page":"855","DOI":"10.1093\/ejcts\/ezaa461","article-title":"Cardiac recovery following left ventricular assist device therapy: experience of complete device explantation including ventricular patch plasty","volume":"59","author":"Gyoten","year":"2021","journal-title":"Eur J Cardiothorac Surg"},{"key":"2023072623092289500_ivad110-B13","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1016\/j.hlc.2017.07.011","article-title":"Percutaneous Decommissioning of Left Ventricular Assist Device","volume":"27","author":"Soon","year":"2018","journal-title":"Heart Lung Circ"},{"key":"2023072623092289500_ivad110-B14","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1097\/MAT.0000000000000926","article-title":"Left Ventricular Assist Device Decommissioning Compared with Explantation for Ventricular Recovery: a Systematic Review","volume":"66","author":"Choi","year":"2020","journal-title":"Asaio J"}],"container-title":["Interdisciplinary CardioVascular and Thoracic Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/icvts\/advance-article-pdf\/doi\/10.1093\/icvts\/ivad110\/50947189\/ivad110.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/icvts\/article-pdf\/37\/1\/ivad110\/50970150\/ivad110.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/icvts\/article-pdf\/37\/1\/ivad110\/50970150\/ivad110.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,7,26]],"date-time":"2023-07-26T23:09:45Z","timestamp":1690412985000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/icvts\/article\/doi\/10.1093\/icvts\/ivad110\/7229990"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,7,1]]},"references-count":14,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2023,7,19]]}},"URL":"https:\/\/doi.org\/10.1093\/icvts\/ivad110","relation":{},"ISSN":["2753-670X"],"issn-type":[{"type":"electronic","value":"2753-670X"}],"subject":[],"published-other":{"date-parts":[[2023,7,1]]},"published":{"date-parts":[[2023,7,1]]},"article-number":"ivad110"}}