{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,19]],"date-time":"2026-04-19T23:41:19Z","timestamp":1776642079987,"version":"3.51.2"},"reference-count":0,"publisher":"Oxford University Press (OUP)","license":[{"start":{"date-parts":[[2023,10,9]],"date-time":"2023-10-09T00:00:00Z","timestamp":1696809600000},"content-version":"am","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"Abstract<\/jats:title>\n \n OBJECTIVES<\/jats:title>\n This study aimed to evaluate the safety and efficacy of decortication for stage III drug-resistant tuberculous empyema (TE).<\/jats:p>\n <\/jats:sec>\n \n METHODS<\/jats:title>\n We analyzed all patients with stage III TE who underwent decortication between March 2015 and October 2019 at Wuhan Pulmonary Hospital. The patients were divided into two groups according to drug-susceptibility testing of bronchoscopy lavage fluid, pleural effusion and tissue specimens, including a drug-resistant group and a drug-sensitive group. We collected and comparatively analyzed the preoperative, perioperative, and postoperative data of the two groups to evaluate the safety and efficacy of decortication for stage III drug-resistant TE.<\/jats:p>\n <\/jats:sec>\n \n RESULTS<\/jats:title>\n In total, 135 cases met the inclusion criteria and were enrolled, including 30 cases in the drug-resistant group and 105 cases in the drug-sensitive group. No mortalities were recorded for the entire study population. Compared to the drug-sensitive group, the drug-resistant group was associated with a longer operation time (259.8\u2009\u00b1\u200978.4\u2009min vs 187.2\u2009\u00b1\u200956.0\u2009min, p\u2009=\u20090.00), a larger volume of intraoperative blood loss (300 [200,400\uff3dml vs 200 [130, 300\uff3dml, p\u2009=\u20090.00) and a higher intraoperative transfusion rate (5\/30, 16.7% vs 4\/105, 3.8%, p\u2009=\u20090.04). The rate of complications was significantly higher in the drug-resistant group (23; 76.7%) than in the drug-sensitive group (53; 50.5%) (p\u2009=\u20090.01). Recurrence was not reported in any of the patients. Twenty-three (76.7%) patients in the drug-resistant group and 90 (85.7%) patients in the drug-resistant group recovered to an \u201cExcellent\u201d level, and three cases in each group recovered to an \u201cPoor\u201d level; there was no significant difference between the two groups in surgical effects (p\u2009=\u20090.21).<\/jats:p>\n <\/jats:sec>\n \n CONCLUSIONS<\/jats:title>\n Decortication is a safe, effective and feasible option for patients with stage III drug-resistant TE, although the operation is difficult and risky.<\/jats:p>\n <\/jats:sec>","DOI":"10.1093\/icvts\/ivad166","type":"journal-article","created":{"date-parts":[[2023,10,9]],"date-time":"2023-10-09T14:57:02Z","timestamp":1696863422000},"source":"Crossref","is-referenced-by-count":1,"title":["The safety and efficacy of decortication for stage III drug-resistant tuberculous empyema"],"prefix":"10.1093","author":[{"given":"Li","family":"Yao","sequence":"first","affiliation":[{"name":"Wuhan Pulmonary Hospital Department of Surgery, , Wuhan, China 430000"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bing","family":"Wang","sequence":"additional","affiliation":[{"name":"Wuhan Pulmonary Hospital Department of Surgery, , Wuhan, China 430000"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"XianXiang","family":"Chen","sequence":"additional","affiliation":[{"name":"Wuhan Pulmonary Hospital Department of Surgery, , Wuhan, China 430000"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"QiBin","family":"Liu","sequence":"additional","affiliation":[{"name":"Wuhan Pulmonary Hospital Department of Surgery, , Wuhan, China 430000"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jian","family":"Sheng","sequence":"additional","affiliation":[{"name":"Wuhan Pulmonary Hospital Department of Surgery, , Wuhan, China 430000"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaoyu","family":"Liu","sequence":"additional","affiliation":[{"name":"Wuhan Pulmonary Hospital Department of Surgery, , Wuhan, China 430000"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"XiYong","family":"Dai","sequence":"additional","affiliation":[{"name":"Wuhan Pulmonary Hospital Department of Surgery, , Wuhan, China 430000"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"YuHui","family":"Jiang","sequence":"additional","affiliation":[{"name":"Wuhan Pulmonary Hospital Department of Surgery, , Wuhan, China 430000"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2023,10,9]]},"container-title":["Interdisciplinary CardioVascular and Thoracic Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/icvts\/advance-article-pdf\/doi\/10.1093\/icvts\/ivad166\/51960116\/ivad166.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/icvts\/advance-article-pdf\/doi\/10.1093\/icvts\/ivad166\/51960116\/ivad166.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,9]],"date-time":"2023-10-09T14:57:02Z","timestamp":1696863422000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/icvts\/advance-article\/doi\/10.1093\/icvts\/ivad166\/7301448"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,10,9]]},"references-count":0,"URL":"https:\/\/doi.org\/10.1093\/icvts\/ivad166","relation":{},"ISSN":["2753-670X"],"issn-type":[{"value":"2753-670X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,10,9]]},"article-number":"ivad166"}}