{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T10:18:08Z","timestamp":1782209888750,"version":"3.54.5"},"reference-count":26,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2023,11,6]],"date-time":"2023-11-06T00:00:00Z","timestamp":1699228800000},"content-version":"vor","delay-in-days":5,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"Maxima Medical Center in Eindhoven","award":["10140021910007"],"award-info":[{"award-number":["10140021910007"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,11,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>OBJECTIVES<\/jats:title>\n                  <jats:p>In patients undergoing video-assisted thoracoscopic surgery for pneumothorax, the benefits and risks of single-shot intercostal nerve block as loco-regional analgesia are not well known. We retrospectively compared the effectiveness of intercostal nerve blocks as a viable alternative to thoracic epidural analgesia (TEA) regarding pain control and enhanced recovery.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>METHODS<\/jats:title>\n                  <jats:p>A retrospective multicentre analysis with single-centre propensity score matching was performed in patients undergoing video-assisted thoracoscopic surgery for pneumothorax receiving either TEA or intercostal nerve block. The primary outcome was a proportion of pain scores \u22654 (scale 0\u201310) until postoperative day (POD) 3. Secondary outcomes included variation in pain over time, additional opioid use, length of stay, mobility, complications and recurrence rate.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>RESULTS<\/jats:title>\n                  <jats:p>In 218 patients, TEA was compared to intercostal nerve block and showed no difference in the proportion of pain scores \u22654 {14.3% [interquartile range (IQR) 0.0\u201333.3] vs 11.1% (IQR 0.0\u201327.3) respectively, P\u2009=\u20090.24}, more frequently needed additional opioids on the day of surgery (18% vs 48%) and first POD (20% vs 42%), had a shorter length of stay (4.0\u2009days [IQR 3.0\u20137.0] vs 3.0\u2009days [IQR 2.8\u20134.0]) and were significantly more mobile until POD 3, while having similar recurrences. Intercostal nerve block had higher pain scores early in the course whereas TEA had higher late (rebound) pain scores.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>CONCLUSIONS<\/jats:title>\n                  <jats:p>In a multimodal analgesic setting with additional opioids, intercostal nerve block shows comparable moments of unacceptable pain from POD 0\u20133 compared to TEA and is linked to improved mobility. Results require randomized confirmation.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/icvts\/ivad180","type":"journal-article","created":{"date-parts":[[2023,11,9]],"date-time":"2023-11-09T11:45:29Z","timestamp":1699530329000},"source":"Crossref","is-referenced-by-count":5,"title":["Pain management after pneumothorax surgery: intercostal nerve block or thoracic epidural analgesia"],"prefix":"10.1093","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8667-3780","authenticated-orcid":false,"given":"Louisa N","family":"Spaans","sequence":"first","affiliation":[{"name":"Department of Surgery, Maxima Medical Center , Eindhoven, Netherlands"},{"name":"Department of Epidemiology and Data Science, Amsterdam University Medical Centers, University of Amsterdam , Amsterdam, Netherlands"},{"name":"Methodology, Amsterdam Public Health , Amsterdam, Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Quirine C A","family":"van Steenwijk","sequence":"additional","affiliation":[{"name":"Department of Surgery, Maxima Medical Center , Eindhoven, Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adelina","family":"Seiranjan","sequence":"additional","affiliation":[{"name":"Department of Surgery, Maxima Medical Center , Eindhoven, Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicky","family":"Janssen","sequence":"additional","affiliation":[{"name":"Department of Surgery, Zuyderland Medical Centre , Heerlen, Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6313-2658","authenticated-orcid":false,"given":"Erik R","family":"de Loos","sequence":"additional","affiliation":[{"name":"Department of Surgery, Zuyderland Medical Centre , Heerlen, Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Denis","family":"Susa","sequence":"additional","affiliation":[{"name":"Department of Surgery, Bravis Hospital , Bergen op Zoom, Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan P","family":"Eerenberg","sequence":"additional","affiliation":[{"name":"Department of Surgery, Tergooi Medical Centre , Hilversum, Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R A (Arthur)","family":"Bouwman","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Pain Medicine, Catharina Hospital , Eindhoven, Netherlands"},{"name":"Department of Electrical Engineering, Signal Processing Systems, Eindhoven Technical University , Eindhoven, Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcel G","family":"Dijkgraaf","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Data Science, Amsterdam University Medical Centers, University of Amsterdam , Amsterdam, Netherlands"},{"name":"Methodology, Amsterdam Public Health , Amsterdam, Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank J C","family":"van den Broek","sequence":"additional","affiliation":[{"name":"Department of Surgery, Maxima Medical Center , Eindhoven, Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2023,11,6]]},"reference":[{"key":"2023111420514007500_ivad180-B1","doi-asserted-by":"crossref","first-page":"284","DOI":"10.3346\/jkms.2008.23.2.284","article-title":"Effects of additional pleurodesis with dextrose and talc-dextrose solution after video assisted thoracoscopic procedures for primary spontaneous pneumothorax","volume":"23","author":"Chung","year":"2008","journal-title":"J Korean Med Sci"},{"key":"2023111420514007500_ivad180-B2","doi-asserted-by":"crossref","first-page":"1790","DOI":"10.1016\/j.athoracsur.2014.06.034","article-title":"Mechanical pleurodesis does not reduce recurrence of spontaneous pneumothorax: a randomized 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