{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T16:05:13Z","timestamp":1775059513663,"version":"3.50.1"},"reference-count":25,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2024,5,16]],"date-time":"2024-05-16T00:00:00Z","timestamp":1715817600000},"content-version":"vor","delay-in-days":15,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,5,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>OBJECTIVES<\/jats:title>\n                  <jats:p>The aim of this study was to evaluate the efficacy of a multimodal preemptive analgesia management approach, specifically incorporating ultrasound-guided thoracic paravertebral block (UG-TPVB) in conjunction with intravenous analgesia, after video-assisted thoracoscopic (VATS) lobectomy under the guidance of enhanced recovery after surgery.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>METHODS<\/jats:title>\n                  <jats:p>A total of 690 patients who underwent VATS lobectomy between October 2021 and March 2022 were divided into the UG-TPVB group (group T, n\u2009=\u2009345) and the control group (group C, n\u2009=\u2009345). Patients in group T received UG-TPVB prior to the induction of general anaesthesia, while group C did not undergo nerve block. A comparison was conducted between the 2 groups regarding various indicators, including postoperative sedation, static\/dynamic numeric rating scale scores, intraoperative fentanyl consumption, duration of mechanical ventilation\/anaesthesia recovery\/hospitalization, postoperative complications and other relevant factors.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>RESULTS<\/jats:title>\n                  <jats:p>The static\/dynamic numeric rating scale scores of group T were lower than those of group C after surgery. Intraoperative fentanyl consumption in group T (0.384\u2009\u00b1\u20090.095\u2009mg) was lower than that in group C (0.465\u2009\u00b1\u20090.053\u2009mg). The duration of mechanical ventilation, anaesthesia recovery and hospitalization were significantly shorter in group T compared to group C. Patient satisfaction rate in group T (70.1%) was higher than that in group C (53.6%). All differences were statistically significant (P\u2009&amp;lt;\u20090.05).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>CONCLUSIONS<\/jats:title>\n                  <jats:p>The multimodal preemptive analgesia management strategy effectively reduces postoperative pain, decreases opioid consumption and promotes faster recovery in patients undergoing VATS lobectomy.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/icvts\/ivae096","type":"journal-article","created":{"date-parts":[[2024,5,15]],"date-time":"2024-05-15T14:23:05Z","timestamp":1715782985000},"source":"Crossref","is-referenced-by-count":3,"title":["Optimizing patient outcomes: the impact of multimodal preemptive analgesia in video-assisted thoracoscopic lobectomy"],"prefix":"10.1093","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-7645-149X","authenticated-orcid":false,"given":"Bing","family":"Li","sequence":"first","affiliation":[{"name":"Department of Anesthesiology, Jiangsu Province Hospital and First Affiliated Hospital with Nanjing Medical University , Nanjing City, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yu","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, Jiangsu Province Hospital and First Affiliated Hospital with Nanjing Medical University , Nanjing City, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rong","family":"Ma","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, Jiangsu Province Hospital and First Affiliated Hospital with Nanjing Medical University , Nanjing City, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2024,5,16]]},"reference":[{"key":"2024052823525545300_ivae096-B1","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1093\/ejcts\/ezt525","article-title":"Regional analgesia for video-assisted thoracic surgery: a systematic review","volume":"45","author":"Steinthorsdottir","year":"2014","journal-title":"Eur J Cardiothorac Surg"},{"key":"2024052823525545300_ivae096-B2","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1016\/j.jtcvs.2020.01.105","article-title":"Comparison of video-assisted thoracoscopic surgery with thoracotomy in bronchial sleeve lobectomy for centrally located non-small cell lung cancer","volume":"161","author":"Xie","year":"2021","journal-title":"J Thorac Cardiovasc Surg"},{"key":"2024052823525545300_ivae096-B3","doi-asserted-by":"crossref","first-page":"1209","DOI":"10.1093\/ejcts\/ezz224","article-title":"What counts more: the patient, the surgical technique, or the hospital? A multivariable analysis of factors affecting perioperative complications of pulmonary lobectomy by video-assisted thoracoscopic surgery from a large nationwide registry","volume":"56","author":"Infante","year":"2019","journal-title":"Eur J Cardiothorac Surg"},{"key":"2024052823525545300_ivae096-B4","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.ijsu.2018.07.006","article-title":"Investigation of single-dose thoracic paravertebral analgesia for postoperative pain control after thoracoscopic lobectomy\u2014a randomized controlled trial","volume":"57","author":"Ding","year":"2018","journal-title":"Int J Surg"},{"key":"2024052823525545300_ivae096-B5","doi-asserted-by":"crossref","DOI":"10.1093\/icvts\/ivac271","article-title":"Is video-assisted thoracoscopic surgery comparable with thoracotomy in perioperative and long-term survival outcomes for non-small-cell lung cancer after neoadjuvant treatment?","volume":"35","author":"Wang","year":"2022","journal-title":"Interact 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