{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T18:16:45Z","timestamp":1792174605822,"version":"4.4.0"},"reference-count":30,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2024,7,11]],"date-time":"2024-07-11T00:00:00Z","timestamp":1720656000000},"content-version":"vor","delay-in-days":10,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/100007330","name":"AtriCure","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007330","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,7,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>OBJECTIVES<\/jats:title>\n                  <jats:p>Thoracoscopic ablation has proven to be an effective and safe rhythm control strategy, especially for persistent atrial fibrillation. However, its impact on quality of life (QoL) and potential gender differences remains unclear.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>METHODS<\/jats:title>\n                  <jats:p>This prospective, single-centre observational study included consecutive patients with symptomatic atrial fibrillation undergoing thoracoscopic ablation. QoL was measured using the Short Form 36 (SF-36) and Atrial Fibrillation Effect on Quality-of-Life (AFEQT) questionnaires and longitudinal trend analysis including linear mixed models was used to assess gender-specific differences.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>RESULTS<\/jats:title>\n                  <jats:p>A total of 191 patients were included; mean age 63.9\u2009\u00b1\u20098.6\u2009years, 61 (31.9%) women and 148 (77.5%) with non-paroxysmal atrial fibrillation. Women were older, more symptomatic and reported lower baseline QoL. AFEQT summary scores substantially improved after three months (relative increase 51.5% from baseline; P\u2009&amp;lt;\u20090.001) and persisted up to 1-year (57.2%; P\u2009&amp;lt;\u20090.001). Women showed substantial QoL improvement, which was comparable to men at 1\u2009year. Distinct gender-related trajectories for AFEQT were observed. Women showed more often clinically important decline over time, yet AF recurrence and age were predictive factors in both men and women. Patients with AF recurrence also experienced QoL improvements, albeit to a lesser extent than those in sinus rhythm (61.3% vs 26.9%, P &amp;lt; 0.001), with no differences between men and women.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>CONCLUSIONS<\/jats:title>\n                  <jats:p>Thoracoscopic ablation for atrial fibrillation results in substantial QoL improvement and was comparable for men and women. Understanding sex-specific and age-related trajectories is important to further enhance patient-centred atrial fibrillation care.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/icvts\/ivae132","type":"journal-article","created":{"date-parts":[[2024,7,12]],"date-time":"2024-07-12T01:39:34Z","timestamp":1720748374000},"source":"Crossref","is-referenced-by-count":3,"title":["Quality of life improvement from thoracoscopic atrial fibrillation ablation in women versus men: a prospective cohort study"],"prefix":"10.1093","volume":"39","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3510-665X","authenticated-orcid":false,"given":"Lara M","family":"Vos","sequence":"first","affiliation":[{"name":"Department of Cardiothoracic Surgery, Erasmus Medical Center , Rotterdam, the Netherlands"},{"name":"Department of Cardiothoracic Surgery, St Antonius Hospital , Nieuwegein, the Netherlands"},{"name":"Department of Cardiothoracic Surgery, Amsterdam University Medical Centers , Amsterdam, the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rein","family":"Vos","sequence":"additional","affiliation":[{"name":"Department of Methodology and Statistics, CAPHRI School for Public Health and Primary Care, Maastricht University Medical Center , Maastricht, the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pythia T","family":"Nieuwkerk","sequence":"additional","affiliation":[{"name":"Department of Medical Psychology, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam Public Health Research Institute , Amsterdam, the Netherlands"},{"name":"Amsterdam Institute for Infection and Immunity, Amsterdam University Medical Centers , Amsterdam, the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter-Paul W K","family":"Vos","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, St Antonius Hospital , Nieuwegein, the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frederik N","family":"Hofman","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, St Antonius Hospital , Nieuwegein, the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert J M","family":"Klautz","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, Amsterdam University Medical Centers , Amsterdam, the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bart P","family":"Van Putte","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, St Antonius Hospital , Nieuwegein, the Netherlands"},{"name":"Department of Cardiothoracic Surgery, Amsterdam University Medical Centers , Amsterdam, the 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