{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T12:03:13Z","timestamp":1753876993669,"version":"3.41.2"},"reference-count":15,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2024,11,19]],"date-time":"2024-11-19T00:00:00Z","timestamp":1731974400000},"content-version":"vor","delay-in-days":18,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,11,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>OBJECTIVES<\/jats:title>\n                  <jats:p>To evaluate the feasibility, safety and quality of robotic-assisted mitral valve repair in complex versus non-complex cases during the early phase of a programme.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>METHODS<\/jats:title>\n                  <jats:p>Since the programme launch in September 2021 until February 2024, 100 patients underwent robotic-assisted mitral valve repair. Of them, 21 patients had complex repairs, while 79 had non-complex repairs. The median age was 58\u2009years for complex cases and 61\u2009years for non-complex cases (P\u2009=\u20090.36).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>RESULTS<\/jats:title>\n                  <jats:p>Bileaflet prolapse was significantly more prevalent in the complex group (52.4% vs 12.7%, P\u2009&amp;lt;\u20090.001). Neochord placement (61.9% vs 13.9%, P\u2009&amp;lt;\u20090.001) and commissuroplasty (28.6% vs 5.1%, P\u2009=\u20090.005) were more frequent in the complex group. The complex group had longer cardiopulmonary bypass times (161 vs 141\u2009min, P\u2009&amp;lt;\u20090.001), aortic cross-clamp times (123 vs 102\u2009min, P\u2009&amp;lt;\u20090.001) and leaflet repair times (43 vs 24\u2009min, P\u2009&amp;lt;\u20090.001). Second pump runs were required more often for complex cases (23.8% vs 3.8%, P\u2009=\u20090.01). All patients left the operating room with residual mitral regurgitation of mild or less. Fewer complex patients were extubated in the operating room (42.9% vs 70.9%, P\u2009=\u20090.02), yet hospital stay was similar (4 vs 4\u2009days, P\u2009=\u20090.56). There were no significant differences in postoperative adverse events. There were no differences in mitral regurgitation of mild or less 4\u2009weeks post-surgery (95.2% vs 98.7%, P\u2009=\u20090.47).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>CONCLUSIONS<\/jats:title>\n                  <jats:p>Complex mitral valve repair can be safely and effectively performed with robotic assistance, even in the early phase of a programme. Despite longer operative and ventilation times in the complex group, hospital stay and postoperative adverse events remained similar.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/icvts\/ivae182","type":"journal-article","created":{"date-parts":[[2024,11,19]],"date-time":"2024-11-19T06:51:58Z","timestamp":1731999118000},"source":"Crossref","is-referenced-by-count":0,"title":["Feasibility, safety and quality of complex mitral valve repair in the early phase of a robotic surgery programme"],"prefix":"10.1093","volume":"39","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8815-9029","authenticated-orcid":false,"given":"Kei","family":"Kobayashi","sequence":"first","affiliation":[{"name":"Division of Cardiac Surgery, Department of Cardiothoracic Surgery, University of Pittsburgh and UPMC Heart and Vascular Institute , Pittsburgh, PA,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yizhan","family":"Guo","sequence":"additional","affiliation":[{"name":"Division of Cardiac Surgery, Department of Cardiothoracic Surgery, University of Pittsburgh and UPMC Heart and Vascular Institute , Pittsburgh, PA,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"suffix":"Jr","given":"Thomas E","family":"Rubino","sequence":"additional","affiliation":[{"name":"Division of Cardiac Surgery, Department of Cardiothoracic Surgery, University of Pittsburgh and UPMC Heart and Vascular Institute , Pittsburgh, PA,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luis E","family":"Ramirez","sequence":"additional","affiliation":[{"name":"Division of Cardiac Surgery, Department of Cardiothoracic Surgery, University of Pittsburgh and UPMC Heart and Vascular Institute , Pittsburgh, PA,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephen D","family":"Waterford","sequence":"additional","affiliation":[{"name":"Division of Cardiac Surgery, Department of Cardiothoracic Surgery, University of Pittsburgh and UPMC Heart and Vascular Institute , Pittsburgh, PA,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ibrahim","family":"Sultan","sequence":"additional","affiliation":[{"name":"Division of Cardiac Surgery, Department of Cardiothoracic Surgery, University of Pittsburgh and UPMC Heart and Vascular Institute , Pittsburgh, PA,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Victor D","family":"Morell","sequence":"additional","affiliation":[{"name":"Division of Cardiac Surgery, Department of Cardiothoracic Surgery, University of Pittsburgh and UPMC Heart and Vascular Institute , Pittsburgh, PA,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6577-649X","authenticated-orcid":false,"given":"Johannes","family":"Bonatti","sequence":"additional","affiliation":[{"name":"Division of Cardiac Surgery, Department of Cardiothoracic Surgery, University of Pittsburgh and UPMC Heart and Vascular Institute , Pittsburgh, PA,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2024,11,18]]},"reference":[{"key":"2024112116013747600_ivae182-B1","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1093\/icvts\/ivaa271","article-title":"Benefits of robotically-assisted surgery for complex mitral valve repair","volume":"32","author":"Fujita","year":"2021","journal-title":"Interact CardioVasc Thorac Surg"},{"key":"2024112116013747600_ivae182-B2","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1016\/j.jtcvs.2010.09.008","article-title":"Robotic repair of posterior mitral valve prolapse versus conventional approaches: potential realized","volume":"141","author":"Mihaljevic","year":"2011","journal-title":"J Thorac Cardiovasc Surg"},{"key":"2024112116013747600_ivae182-B3","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1016\/j.athoracsur.2023.07.047","article-title":"Robotic mitral valve repair for degenerative mitral regurgitation","volume":"117","author":"Mori","year":"2024","journal-title":"Ann Thorac Surg"},{"key":"2024112116013747600_ivae182-B4","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1093\/ejcts\/ezz029","article-title":"Can complex mitral valve repair be performed with robotics? 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