{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T04:28:32Z","timestamp":1788582512834,"version":"build-2803163510"},"reference-count":78,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2025,2,19]],"date-time":"2025-02-19T00:00:00Z","timestamp":1739923200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,3,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>OBJECTIVES<\/jats:title>\n                  <jats:p>To compare outcomes of two different revascularization strategies in chronic kidney disease (CKD) patients: coronary artery bypass grafting (CABG) versus percutaneous coronary intervention (PCI).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>METHODS<\/jats:title>\n                  <jats:p>We conducted this meta-analysis according to Preferred Reporting Items for Systematic Review and Meta-Analyses guidelines and registered with PROSPERO (CRD42021238659), evaluated studies comparing CABG and PCI in patients with CAD and CKD (defined by KDIGO guidelines). Data were extracted from PubMed, EMBASE and Cochrane from 2000 to 2023. The primary end-point was long-term major adverse cardiovascular and cerebrovascular event rates, with secondary end-points including 30-day mortality, stroke, myocardial infarction (MI) and repeat revascularization. Statistical analyses included Kaplan\u2013Meier estimations, Cox regression, and meta-regression to address heterogeneity. Publication bias was assessed via funnel plots. No funding was received, and the authors report no conflicts of interest.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>RESULTS<\/jats:title>\n                  <jats:p>We included 33 studies with 402\u2009300 patients (eGFR &amp;lt;60\u2009ml\/min\/1.73 m2). The cohort comprised 132\u2009314 coronary artery bypass graft and 269\u2009986 PCI patients. Over 3 years, coronary artery bypass group provided protection against major adverse cardiac and cerebrovascular events, MI, and repeat revascularization compared to PCI. However, PCI showed better short-term outcomes, including lower 30-day mortality. Coronary artery bypass group was linked to a higher stroke risk over the 3-year follow-up.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>CONCLUSIONS<\/jats:title>\n                  <jats:p>Revascularization strategies for CKD and coronary artery disease patients should balance PCI's short-term benefits with CABG\u2019s long-term advantages.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/icvts\/ivaf021","type":"journal-article","created":{"date-parts":[[2025,2,19]],"date-time":"2025-02-19T16:48:00Z","timestamp":1739983680000},"source":"Crossref","is-referenced-by-count":4,"title":["Myocardial revascularization in patients with chronic kidney disease: a systematic review and meta-analysis of surgical versus percutaneous coronary revascularization"],"prefix":"10.1093","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3251-7659","authenticated-orcid":false,"given":"Valentina","family":"Grazioli","sequence":"first","affiliation":[{"name":"Cardio-Thoracic Surgery Department, Maastricht University Medical Centre (MUMC) , Maastricht,","place":["The Netherlands"]},{"name":"Department of Cardiac Surgery, Cliniche Humanitas Gavazzeni , Bergamo,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2611-5626","authenticated-orcid":false,"given":"Michele","family":"Di Mauro","sequence":"additional","affiliation":[{"name":"Faculty of Health, Medicine and Life Sciences, Maastricht University , Maastricht,","place":["The Netherlands"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giacomo","family":"Perocchio","sequence":"additional","affiliation":[{"name":"Division of Cardiac Surgery, Ospedale Policlinico San Martino , Genova,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Piersilvio","family":"Gerometta","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery, Cliniche Humanitas Gavazzeni , Bergamo,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4863-569X","authenticated-orcid":false,"given":"Alfonso","family":"Agnino","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Division of Robotic and Minimally-Invasive Cardiac Surgery, Cliniche Humanitas Gavazzeni , Bergamo,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maurizio","family":"Pin","sequence":"additional","affiliation":[{"name":"Cardiovascular Department, Maria Cecilia Hospital, GVM Care & Research , Cotignola (Ravenna),","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paolo","family":"Meani","sequence":"additional","affiliation":[{"name":"Cardio-Thoracic Surgery Department, Maastricht University Medical Centre (MUMC) , Maastricht,","place":["The Netherlands"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matteo","family":"Matteucci","sequence":"additional","affiliation":[{"name":"Cardio-Thoracic Surgery Department, Maastricht University Medical Centre (MUMC) , Maastricht,","place":["The Netherlands"]},{"name":"Cardiac Surgery Unit, ASST Sette Laghi , Varese,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5250-1796","authenticated-orcid":false,"given":"Daniele","family":"Ronco","sequence":"additional","affiliation":[{"name":"Cardio-Thoracic Surgery Department, Maastricht University Medical Centre (MUMC) , Maastricht,","place":["The Netherlands"]},{"name":"Cardiac Surgery Unit, ASST Grande Ospedale Metropolitano Niguarda , Milano,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giulio","family":"Massimi","sequence":"additional","affiliation":[{"name":"Cardio-Thoracic Surgery Department, Maastricht University Medical Centre (MUMC) , Maastricht,","place":["The Netherlands"]},{"name":"Cardiac Surgery Unit, Santa Maria Hospital , Terni,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos","family":"Maessen","sequence":"additional","affiliation":[{"name":"Cardio-Thoracic Surgery Department, Maastricht University Medical Centre (MUMC) , Maastricht,","place":["The Netherlands"]},{"name":"Cardiovascular Research Institute Maastricht (CARIM) , Maastricht,","place":["The Netherlands"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8836-4778","authenticated-orcid":false,"given":"Domenico","family":"Corradi","sequence":"additional","affiliation":[{"name":"Department of Medicine and Surgery, Unit of Pathology, University of Parma , Parma,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4680-0815","authenticated-orcid":false,"given":"Mario","family":"Gaudino","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, Weill Cornell Medicine, Presbyterian Hospital , New York, NY,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberto","family":"Lorusso","sequence":"additional","affiliation":[{"name":"Cardio-Thoracic Surgery Department, Maastricht University Medical Centre (MUMC) , Maastricht,","place":["The Netherlands"]},{"name":"Cardiovascular Research Institute Maastricht (CARIM) , 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