{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T16:36:30Z","timestamp":1772123790004,"version":"3.50.1"},"reference-count":14,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2025,2,12]],"date-time":"2025-02-12T00:00:00Z","timestamp":1739318400000},"content-version":"vor","delay-in-days":11,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,2,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>OBJECTIVES<\/jats:title>\n                  <jats:p>Mortality in patients with interrupted aortic arch (IAA) rates among the highest in congenital heart surgery. Various techniques for aortic arch repair are described; reintervention rates remain substantial. This retrospective single-centre study aimed to evaluate the long-term outcome in a biventricular series with a preferably performed direct anastomosis and one-stage repair.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>METHODS<\/jats:title>\n                  <jats:p>At the Children\u2019s Heart Center Linz, 58 biventricular patients with IAA were operated between 1999 and 2023. Median age at operation was 10 [7; 15] days and weight was 3.3 [3; 3.7] kg. In the 24 children with ventricular septal defects (VSDs) only, the arch was repaired by a direct anastomosis. Thirty-four had complex concomitant heart defects, and the arch reconstruction was performed by direct anastomosis (20), direct anastomosis + patch (10), reverse subclavian flap + patch (3) and aortic autograft + patch (1).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>RESULTS<\/jats:title>\n                  <jats:p>Median cardiopulmonary bypass time was 222 [159; 315] min, and aortic cross-clamp time was 94 [75; 143] min. Two patients died during the hospital stay (4%), two patients after discharge (4%), and four (7%) required an arch reintervention during a follow-up period of median 9.3 [6.2; 17.2] years. There was no death or arch reintervention in the VSD group.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>CONCLUSIONS<\/jats:title>\n                  <jats:p>All-cause mortality in biventricular patients with IAA was 7%, and the arch reintervention rate was 8%. Direct aortic anastomosis in patients with VSD can only be performed with excellent outcomes, with no deaths or arch reinterventions being observed after a follow-up up to 24\u2009years.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Clinical registration number<\/jats:title>\n                  <jats:p>EK Nr 1268\/2021, Ethics committee of the Medical Faculty at Johannes Kepler University Linz.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/icvts\/ivaf026","type":"journal-article","created":{"date-parts":[[2025,2,12]],"date-time":"2025-02-12T16:06:21Z","timestamp":1739376381000},"source":"Crossref","is-referenced-by-count":1,"title":["Long-term outcome after repair of interrupted aortic arch in a single centre"],"prefix":"10.1093","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7499-7646","authenticated-orcid":false,"given":"Michaela","family":"Kreuzer","sequence":"first","affiliation":[{"name":"Division of Pediatric and Congenital Heart Surgery, Kepler University Hospital , Linz,","place":["Austria"]},{"name":"Medical Faculty, Johannes Kepler University Linz , Linz,","place":["Austria"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eva","family":"Sames-Dolzer","sequence":"additional","affiliation":[{"name":"Division of Pediatric and Congenital Heart Surgery, Kepler University Hospital , Linz,","place":["Austria"]},{"name":"Medical Faculty, Johannes Kepler University Linz , Linz,","place":["Austria"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andreas","family":"Tulzer","sequence":"additional","affiliation":[{"name":"Medical Faculty, Johannes Kepler University Linz , Linz,","place":["Austria"]},{"name":"Department of Pediatric Cardiology, Kepler University Hospital , Linz,","place":["Austria"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Melanie","family":"Klapper","sequence":"additional","affiliation":[{"name":"Division of Pediatric and Congenital Heart Surgery, Kepler University Hospital , Linz,","place":["Austria"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roland","family":"Mair","sequence":"additional","affiliation":[{"name":"Division of Pediatric and Congenital Heart Surgery, Kepler University Hospital , Linz,","place":["Austria"]},{"name":"Medical Faculty, Johannes Kepler University Linz , Linz,","place":["Austria"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6358-5048","authenticated-orcid":false,"given":"Gregor","family":"Gierlinger","sequence":"additional","affiliation":[{"name":"Division of Pediatric and Congenital Heart Surgery, Kepler University Hospital , Linz,","place":["Austria"]},{"name":"Medical Faculty, Johannes Kepler University Linz , Linz,","place":["Austria"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fabian","family":"Seeber","sequence":"additional","affiliation":[{"name":"Division of Pediatric and Congenital Heart Surgery, Kepler University Hospital , Linz,","place":["Austria"]},{"name":"Medical Faculty, Johannes Kepler University Linz , Linz,","place":["Austria"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0935-1766","authenticated-orcid":false,"given":"Rudolf","family":"Mair","sequence":"additional","affiliation":[{"name":"Division of Pediatric and Congenital Heart Surgery, Kepler University Hospital , Linz,","place":["Austria"]},{"name":"Medical Faculty, Johannes Kepler University Linz , Linz,","place":["Austria"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2025,2,12]]},"reference":[{"key":"2025030500011501300_ivaf026-B1","doi-asserted-by":"crossref","first-page":"2050","DOI":"10.1016\/j.athoracsur.2020.05.146","article-title":"Outcomes of interrupted aortic arch repair in children with biventricular circulation","volume":"111","author":"Andrianova","year":"2021","journal-title":"Ann Thorac Surg"},{"key":"2025030500011501300_ivaf026-B2","doi-asserted-by":"crossref","first-page":"1819","DOI":"10.1016\/j.athoracsur.2018.01.035","article-title":"Long-term outcome of interrupted arch repair with direct anastomosis and homograft augmentation patch","volume":"105","author":"Uzzaman","year":"2018","journal-title":"Ann Thorac Surg"},{"key":"2025030500011501300_ivaf026-B3","doi-asserted-by":"crossref","first-page":"942","DOI":"10.1016\/j.jtcvs.2009.09.069","article-title":"Twenty-three years of single-stage end-to-side anastomosis repair of interrupted aortic arches","volume":"139","author":"Hussein","year":"2010","journal-title":"J Thorac Cardiovasc Surg"},{"key":"2025030500011501300_ivaf026-B4","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1016\/j.jtcvs.2004.10.004","article-title":"Risk factors associated with mortality and interventions in 472 neonates with interrupted aortic arch: a Congenital Heart Surgeons Society study","volume":"129","author":"McCrindle","year":"2005","journal-title":"J Thorac Cardiovasc Surg"},{"key":"2025030500011501300_ivaf026-B5","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1016\/j.athoracsur.2024.02.009","article-title":"Long-term outcomes after interrupted aortic arch repair","volume":"118","author":"Miller","year":"2024","journal-title":"Ann Thorac Surg"},{"key":"2025030500011501300_ivaf026-B6","doi-asserted-by":"crossref","first-page":"742","DOI":"10.1093\/icvts\/ivy147","article-title":"Double-arterial cannulation: a strategy for whole body perfusion during aortic arch reconstruction","volume":"27","author":"Kreuzer","year":"2018","journal-title":"Interact CardioVasc Thorac Surg"},{"key":"2025030500011501300_ivaf026-B7","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1093\/ejcts\/ezab433","article-title":"Aortic arch reconstruction in the Norwood procedure using a curved polytetrafluorethylene patch","volume":"61","author":"Sames-Dolzer","year":"2022","journal-title":"Eur J Cardiothorac Surg"},{"key":"2025030500011501300_ivaf026-B8","doi-asserted-by":"crossref","first-page":"1577","DOI":"10.1016\/j.athoracsur.2006.05.105","article-title":"Interrupted aortic arch repair: aortic arch advancement without a patch minimizes arch reinterventions","volume":"82","author":"Morales","year":"2006","journal-title":"Ann Thorac Surg"},{"key":"2025030500011501300_ivaf026-B9","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1093\/ejcts\/ezy030","article-title":"The Ross-Konno procedure in neonates and infants less than 3 months of age","volume":"54","author":"Sames-Dolzer","year":"2018","journal-title":"Eur J Cardiothorac Surg"},{"key":"2025030500011501300_ivaf026-B10","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1093\/ejcts\/ezz136","article-title":"High prevalence of early arch reobstruction after arch repair in patients with anomalous right subclavian artery","volume":"57","author":"Ravintharan","year":"2020","journal-title":"Eur J Cardiothorac Surg"},{"key":"2025030500011501300_ivaf026-B11","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1016\/j.ijcard.2020.11.018","article-title":"Post-operative musculoskeletal outcomes in patients with coarctation of the aorta following different surgical approaches","volume":"327","author":"Kr\u00f6\u00f6nstr\u00f6m","year":"2021","journal-title":"Int J Cardiol"},{"key":"2025030500011501300_ivaf026-B12","doi-asserted-by":"crossref","first-page":"953","DOI":"10.1016\/0735-1097(89)90472-5","article-title":"Left subclavian flap aortoplasty for coarctation of the aorta: effects on forearm vascular function and growth","volume":"14","author":"Shenberger","year":"1989","journal-title":"J Am Coll Cardiol"},{"key":"2025030500011501300_ivaf026-B13","doi-asserted-by":"crossref","first-page":"856","DOI":"10.1017\/S1047951119000386","article-title":"Left arm structure and function late after subclavian flap repair of aortic coarctation in childhood","volume":"29","author":"Dennis","year":"2019","journal-title":"Cardiol Young"},{"key":"2025030500011501300_ivaf026-B14","doi-asserted-by":"crossref","first-page":"ezad038","DOI":"10.1093\/ejcts\/ezad038","article-title":"Long-term follow-up after simultaneous arterial switch operation and aortic arch repair","volume":"63","author":"Kreuzer","year":"2023","journal-title":"Eur J Cardiothorac Surg"}],"container-title":["Interdisciplinary CardioVascular and Thoracic Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/icvts\/advance-article-pdf\/doi\/10.1093\/icvts\/ivaf026\/61861140\/ivaf026.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/icvts\/article-pdf\/40\/2\/ivaf026\/61861140\/ivaf026.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/icvts\/article-pdf\/40\/2\/ivaf026\/61861140\/ivaf026.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,5]],"date-time":"2025-03-05T00:01:35Z","timestamp":1741132895000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/icvts\/article\/doi\/10.1093\/icvts\/ivaf026\/8010469"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2]]},"references-count":14,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2025,2,5]]}},"URL":"https:\/\/doi.org\/10.1093\/icvts\/ivaf026","relation":{},"ISSN":["2753-670X"],"issn-type":[{"value":"2753-670X","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2025,2]]},"published":{"date-parts":[[2025,2]]},"article-number":"ivaf026"}}