{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T12:02:26Z","timestamp":1753876946165,"version":"3.41.2"},"reference-count":23,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2025,4,11]],"date-time":"2025-04-11T00:00:00Z","timestamp":1744329600000},"content-version":"vor","delay-in-days":13,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100007514","name":"University of Pisa","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100007514","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,3,29]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>OBJECTIVES<\/jats:title>\n                  <jats:p>Benign tracheal stenosis, as a complication of intubation or tracheotomy, is a rare but life-threatening condition. Surgical resection with end-to-end anastomosis is considered the standard treatment, when possible, providing satisfactory results in over 90% of cases. However, limited research has focused on assessing the subjective perception of quality of life (QoL) following this surgical intervention.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>METHODS<\/jats:title>\n                  <jats:p>This study involved patients who underwent surgical treatment for tracheal stenosis at the Thoracic Surgery Unit of Pisa over a 10-year period, including 12 patients treated after March 2020 during the peak of the Covid-19 pandemic. A dedicated mixed-method questionnaire was administered to evaluate short-term perceived QoL across three domains: general functionality, organ-specific functionality and psychological well-being. The assessment was performed both before surgery (PRE-period) and 3 months after surgery (POST-period).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>RESULTS<\/jats:title>\n                  <jats:p>The study included 22 patients and found a significant overall improvement in QoL following surgery, with a mean total score reduction of \u221214.64 (95% CI: \u221218.45 to 10.90, P\u2009&amp;lt;\u20090.001). General functionality and psychological well-being scores improved notably, with POST-PRE differences of \u22127.59 (95% CI: \u22129.22 to 5.68, P\u2009=\u20090.015) and \u22123.18 (95% CI: \u22124.22 to 1.91; P\u2009=\u20090.046), respectively. Patients with a history of Covid-19 showed greater improvements in general functionality (P\u2009=\u20090.042) and psychological well-being (P\u2009=\u20090.043) than others.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>CONCLUSIONS<\/jats:title>\n                  <jats:p>Surgical intervention for tracheal stenosis significantly enhances perceived patients\u2019 QoL, particularly in general functionality and psychological well-being areas. The results indicate that patients with a history of Covid-19 may experience a more pronounced recovery. Despite the risk of early postoperative complications, the overall improvement in QoL supports the effectiveness of surgical treatment.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/icvts\/ivaf090","type":"journal-article","created":{"date-parts":[[2025,4,11]],"date-time":"2025-04-11T16:59:21Z","timestamp":1744390761000},"source":"Crossref","is-referenced-by-count":0,"title":["Short-term perceived quality of life after surgical resection for benign tracheal stenosis: a pre-post intervention study"],"prefix":"10.1093","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8538-1719","authenticated-orcid":false,"given":"Vittorio","family":"Aprile","sequence":"first","affiliation":[{"name":"Division of Thoracic Surgery, Cardiac, Thoracic, and Vascular Department, University Hospital of Pisa , Pisa,","place":["Italy"]},{"name":"Department of Surgical, Medical and Molecular Pathology and Critical Care Medicine, University of Pisa , Pisa,","place":["Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5706-0974","authenticated-orcid":false,"given":"Diana","family":"Bacchin","sequence":"additional","affiliation":[{"name":"Department of Surgical, Medical and Molecular Pathology and Critical Care Medicine, University of Pisa , Pisa,","place":["Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alessandra","family":"Lenzini","sequence":"additional","affiliation":[{"name":"Division of Thoracic Surgery, Cardiac, Thoracic, and Vascular Department, University Hospital of Pisa , Pisa,","place":["Italy"]},{"name":"Department of Surgical, Medical and Molecular Pathology and Critical Care Medicine, University of Pisa , Pisa,","place":["Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Giovanna","family":"Mastromarino","sequence":"additional","affiliation":[{"name":"Division of Thoracic Surgery, Cardiac, Thoracic, and Vascular Department, University Hospital of Pisa , Pisa,","place":["Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stylianos","family":"Korasidis","sequence":"additional","affiliation":[{"name":"Division of Thoracic Surgery, Cardiac, Thoracic, and Vascular Department, University Hospital of Pisa , Pisa,","place":["Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sara","family":"Gabriele","sequence":"additional","affiliation":[{"name":"Department of Surgical, Medical and Molecular Pathology and Critical Care Medicine, University of Pisa , Pisa,","place":["Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alessandro","family":"Ribechini","sequence":"additional","affiliation":[{"name":"Division of Thoracic Surgery, Cardiac, Thoracic, and Vascular Department, University Hospital of Pisa , Pisa,","place":["Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mario","family":"Milazzo","sequence":"additional","affiliation":[{"name":"Department of Civil and Industrial Engineering, University of Pisa , Pisa,","place":["Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcello Carlo","family":"Ambrogi","sequence":"additional","affiliation":[{"name":"Division of Thoracic Surgery, Cardiac, Thoracic, and Vascular Department, University Hospital of Pisa , Pisa,","place":["Italy"]},{"name":"Department of Surgical, Medical and Molecular Pathology and Critical Care Medicine, University of Pisa , Pisa,","place":["Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9909-6820","authenticated-orcid":false,"given":"Marco","family":"Lucchi","sequence":"additional","affiliation":[{"name":"Division of Thoracic Surgery, Cardiac, Thoracic, and Vascular Department, University Hospital of Pisa , Pisa,","place":["Italy"]},{"name":"Department of Surgical, Medical and Molecular Pathology and Critical Care Medicine, University of Pisa , Pisa,","place":["Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2025,4,11]]},"reference":[{"key":"2025042501563065700_ivaf090-B1","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1510\/icvts.2007.168054","article-title":"Single-staged laryngotracheal resection and reconstruction for benign strictures in adults","volume":"7","author":"Marulli","year":"2008","journal-title":"Interact CardioVasc Thorac Surg"},{"key":"2025042501563065700_ivaf090-B2","doi-asserted-by":"crossref","first-page":"ezae330","DOI":"10.1093\/ejcts\/ezae330","article-title":"Tracheal resection and anastomosis in post-intubation tracheal stenosis: a systematic review","volume":"66","author":"\u00c1lvarez-Maldonado","year":"2024","journal-title":"Eur J Cardiothorac Surg"},{"key":"2025042501563065700_ivaf090-B3","doi-asserted-by":"crossref","first-page":"2099","DOI":"10.21037\/tcr.2020.02.60","article-title":"Quality-of-life evaluation in patients with laryngotracheal diseases","volume":"9","author":"Bibas","year":"2020","journal-title":"Transl Cancer Res"},{"key":"2025042501563065700_ivaf090-B4","doi-asserted-by":"crossref","first-page":"1834","DOI":"10.1016\/j.athoracsur.2020.07.046","article-title":"Long-term results and functional outcomes after surgical repair of benign laryngotracheal stenosis","volume":"111","author":"Nauta","year":"2021","journal-title":"Ann Thorac Surg"},{"key":"2025042501563065700_ivaf090-B5","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1186\/s40248-018-0147-2","article-title":"State of the art in tracheal surgery: a brief literature review","volume":"13","author":"Siciliani","year":"2018","journal-title":"Multidiscip Respir Med"},{"key":"2025042501563065700_ivaf090-B6","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1016\/j.xjtc.2020.08.023","article-title":"Laryngotracheal resection for a post-tracheotomy stenosis in a patient with coronavirus disease 2019 (COVID-19)","volume":"4","author":"Lucchi","year":"2020","journal-title":"JTCVS Tech"},{"key":"2025042501563065700_ivaf090-B7","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1093\/ejcts\/ezv471","article-title":"Long-term results of laryngotracheal resection for benign stenosis from a series of 109 consecutive patients","volume":"50","author":"D'Andrilli","year":"2016","journal-title":"Eur J Cardiothorac Surg"},{"key":"2025042501563065700_ivaf090-B8","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/0168-8510(90)90421-9","article-title":"EuroQol\u2014a new facility for the measurement of health-related quality of life","volume":"16","author":"EuroQol Group","year":"1990","journal-title":"Health Policy"},{"key":"2025042501563065700_ivaf090-B9","doi-asserted-by":"crossref","first-page":"1681","DOI":"10.1007\/s13304-023-01577-6","article-title":"Surgical treatment of tracheal stenosis during Covid-19 era: a single-center experience and lessons learnt on the field","volume":"75","author":"Bacchin","year":"2023","journal-title":"Updates Surg"},{"key":"2025042501563065700_ivaf090-B10","first-page":"05133","article-title":"Impact of dyspnea on adults with respiratory symptoms without a defined diagnosis","volume":"S0012-3692","author":"Bierbrier","year":"2024","journal-title":"Chest"},{"key":"2025042501563065700_ivaf090-B11","first-page":"870","article-title":"The development and validation of a dysphagia-specific quality-of-life questionnaire for patients with head and neck cancer: the M. D. Anderson dysphagia inventory","volume":"127","author":"Chen","year":"2001","journal-title":"Arch Otolaryngol Head Neck Surg"},{"key":"2025042501563065700_ivaf090-B12","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1001\/jamaoto.2015.2562","article-title":"Dysphagia following airway reconstruction in adults","volume":"142","author":"Lennon","year":"2016","journal-title":"JAMA Otolaryngol Head Neck Surg"},{"key":"2025042501563065700_ivaf090-B13","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1097\/MOO.0000000000000362","article-title":"Voice and swallowing outcomes for adults undergoing reconstructive surgery for laryngotracheal stenosis","volume":"25","author":"Clunie","year":"2017","journal-title":"Curr Opin Otolaryngol Head Neck Surg"},{"key":"2025042501563065700_ivaf090-B14","doi-asserted-by":"crossref","first-page":"227","DOI":"10.21037\/acs.2018.03.07","article-title":"Functional outcome after (laryngo)tracheal resection and reconstruction for acquired benign (laryngo)tracheal stenosis","volume":"7","author":"Timman","year":"2018","journal-title":"Ann Cardiothorac Surg"},{"key":"2025042501563065700_ivaf090-B15","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1016\/j.chest.2024.06.3804","article-title":"Management of central airway obstruction: an American College of Chest Physicians clinical practice guideline","volume":"167","author":"Mahmood","year":"2025","journal-title":"Chest"},{"key":"2025042501563065700_ivaf090-B16","doi-asserted-by":"crossref","first-page":"1096.e1","DOI":"10.1016\/j.jamda.2017.09.007","article-title":"Management of dyspnea and anxiety in chronic obstructive pulmonary disease: a critical review","volume":"18","author":"Yohannes","year":"2017","journal-title":"J AmMed Dir Assoc"},{"key":"2025042501563065700_ivaf090-B17","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1159\/000519216","article-title":"The value of dyspnea and spirometry in detecting relapse of benign tracheal stenosis","volume":"101","author":"Kossyvaki","year":"2022","journal-title":"Respiration"},{"key":"2025042501563065700_ivaf090-B18","doi-asserted-by":"crossref","first-page":"1075","DOI":"10.1001\/jamaoto.2016.2029","article-title":"Evaluation of dyspnea outcomes after endoscopic airway surgery for laryngotracheal stenosis","volume":"142","author":"Samad","year":"2016","journal-title":"JAMA Otolaryngol Head Neck Surg"},{"key":"2025042501563065700_ivaf090-B19","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1016\/j.bbi.2020.05.048","article-title":"Covid-19 pandemic and mental health consequences: systematic review of the current evidence","volume":"89","author":"Vindegaard","year":"2020","journal-title":"Brain Behav Immun"},{"key":"2025042501563065700_ivaf090-B20","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1001\/jamaoto.2020.4148","article-title":"Evaluation of the incidence and potential mechanisms of tracheal complications in patients with Covid-19","volume":"147","author":"Fiacchini","year":"2021","journal-title":"JAMA Otolaryngol Head Neck Surg"},{"key":"2025042501563065700_ivaf090-B21","doi-asserted-by":"crossref","first-page":"ezae026","DOI":"10.1093\/ejcts\/ezae026","article-title":"Surgery for tracheal and laryngotracheal stenosis: a historical case series","volume":"65","author":"Mammana","year":"2024","journal-title":"Eur J Cardiothorac Surg"},{"key":"2025042501563065700_ivaf090-B22","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1510\/icvts.2009.202978","article-title":"The etiological factors of recurrence after tracheal resection and reconstruction in post-intubation stenosis","volume":"9","author":"Abbasidezfouli","year":"2009","journal-title":"Interact CardioVasc Thorac Surg"},{"key":"2025042501563065700_ivaf090-B23","doi-asserted-by":"crossref","first-page":"983","DOI":"10.1510\/icvts.2009.213215","article-title":"Urgent segmental resection as the primary strategy in management of benign tracheal stenosis. A single center experience in 164 consecutive cases","volume":"9","author":"Krajc","year":"2009","journal-title":"Interact CardioVasc Thorac Surg"}],"container-title":["Interdisciplinary CardioVascular and Thoracic Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/icvts\/advance-article-pdf\/doi\/10.1093\/icvts\/ivaf090\/62916243\/ivaf090.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/icvts\/article-pdf\/40\/4\/ivaf090\/62916243\/ivaf090.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/icvts\/article-pdf\/40\/4\/ivaf090\/62916243\/ivaf090.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,25]],"date-time":"2025-04-25T05:56:43Z","timestamp":1745560603000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/icvts\/article\/doi\/10.1093\/icvts\/ivaf090\/8111574"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3,29]]},"references-count":23,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2025,3,29]]}},"URL":"https:\/\/doi.org\/10.1093\/icvts\/ivaf090","relation":{},"ISSN":["2753-670X"],"issn-type":[{"type":"electronic","value":"2753-670X"}],"subject":[],"published-other":{"date-parts":[[2025,4]]},"published":{"date-parts":[[2025,3,29]]},"article-number":"ivaf090"}}