{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T15:51:55Z","timestamp":1788537115699,"version":"build-2803163510"},"reference-count":19,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2025,6,2]],"date-time":"2025-06-02T00:00:00Z","timestamp":1748822400000},"content-version":"vor","delay-in-days":1,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,6,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>OBJECTIVES<\/jats:title>\n                  <jats:p>Acute aortic dissection (AAD) commonly occurs with a dilation of the ascending aorta at diameters under the threshold of surgical indication. Aortic diameter\/height index (AHI) has been proposed for risk stratification and more accurate prophylactic surgery.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>METHODS<\/jats:title>\n                  <jats:p>From January 2001 to November 2023, all patients operated on for AAD at our Institute were prospectively collected and retrospectively analysed, calculating the AHI. A Control Group without aortic pathology was stratified for the same risk index, and a modelling risk analysis for aortic dissection was also performed.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>RESULTS<\/jats:title>\n                  <jats:p>A group of 210 patients was operated during the study period, of whom 168 (80%) had a prevalent post-junctional aortic dilation with a mean aortic diameter at the time of diagnosis of 5.1\u2009\u00b1\u20090.7\u2009cm. In 53\/210 (25%), the aortic diameter was &amp;gt; 5.5\u2009cm. According to AHI, 19\/210 patients (9%) were low-risk, 142\/210 (67.6%) moderate, 45\/210 (21.3%) high and 4\/210 (2%) severe risk. In the AHI probability density function, the peak for dissection was 2.93\u2009cm\/m for males and 3.05 for females. Control were 6343 patients (3.2% at moderate risk) with AHI of 2.01\u2009cm\/m. After simulating the dissecting process, 215 (3.3%) had AHI \u2265 2.9\u2009cm\/m.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>CONCLUSIONS<\/jats:title>\n                  <jats:p>The measurement of the aortic diameter to height index in patients with acute aortic dissection revealed a significant prevalence of individuals presenting a moderate risk for acute aortic events. Regardless of absolute aortic diameter values, patients with AHI exceeding 2.9\u2009cm\/m should be referred to an aortic centre for multidisciplinary risk assessment.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/icvts\/ivaf125","type":"journal-article","created":{"date-parts":[[2025,6,2]],"date-time":"2025-06-02T14:23:21Z","timestamp":1748874201000},"source":"Crossref","is-referenced-by-count":3,"title":["Ascending aortic aneurysm and dissection risk: focus on aortic height index"],"prefix":"10.1093","volume":"40","author":[{"given":"Susanna","family":"Grego","sequence":"first","affiliation":[{"name":"Rare Cardiovascular Disease Unit, Cardiocentro Ticino Institute, EOC , Lugano,","place":["Switzerland"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1184-7210","authenticated-orcid":false,"given":"Alberto","family":"Pozzoli","sequence":"additional","affiliation":[{"name":"Heart Surgery Unit, Cardiocentro Ticino Institute, EOC , 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