{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T12:01:11Z","timestamp":1753876871608,"version":"3.41.2"},"reference-count":32,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2025,5,30]],"date-time":"2025-05-30T00:00:00Z","timestamp":1748563200000},"content-version":"vor","delay-in-days":1,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,6,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>OBJECTIVES<\/jats:title>\n                  <jats:p>Peripheral cannula selection in minimally invasive cardiac surgery (MICS) is crucial, as venous drainage limitations during cardiopulmonary bypass (CPB) can impair end-organ perfusion and overall outcomes. This study evaluates the in vivo venous drainage efficiency of different peripheral venous cannulas for adult MICS by applying dynamic similarity (DS) prediction formulas.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>METHODS<\/jats:title>\n                  <jats:p>This observational study included 75 adult MICS patients with use of single peripheral venous cannulation from January 2017 to June 2023. The analysis included cannulas Bio-Medicus Multi XL Life Support, Nextgen Bicaval and Smart cannulas. Cannula performance was assessed by comparing predicted pressures with in vivo measurements.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>RESULTS<\/jats:title>\n                  <jats:p>A total of 278, 314 and 264 measurements were recorded for the Multi, Next and Smart cannulas, respectively. No significant demographic differences were found between groups. Lin\u2019s concordance correlation coefficients for agreement between predicted and measured pressures were &amp;gt;0.95 for the Multi and Next cannulas but substantially lower for the Smart cannula (0.80). Bland-Altman analysis showed a mean bias of \u22121.09\u2009mmHg for the Multi, \u22120.15\u2009mmHg for the Next and 3.68\u2009mmHg for the Smart cannula, with the latter exceeding the \u00b112.5\u2009mmHg limits of agreement.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>CONCLUSIONS<\/jats:title>\n                  <jats:p>DS-based predictions revealed significant performance variability among peripheral venous cannula types. The in vivo performance was adequately predicted for the Multi and Next cannulas but not for the Smart cannula, underscoring the need for real-life evaluations and performance monitoring during CPB. Incorporating dynamic performance assessments into clinical decision-making might optimize venous drainage and patient outcomes.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/icvts\/ivaf127","type":"journal-article","created":{"date-parts":[[2025,5,30]],"date-time":"2025-05-30T04:38:47Z","timestamp":1748579927000},"source":"Crossref","is-referenced-by-count":0,"title":["Clinical assessment of cannula performance during adult minimally invasive valve surgery using predictive mathematical models"],"prefix":"10.1093","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2092-6321","authenticated-orcid":false,"given":"Korneel","family":"Vandewiele","sequence":"first","affiliation":[{"name":"Department of Perfusion, Ghent University Hospital , Ghent,","place":["Belgium"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Filip","family":"De Somer","sequence":"additional","affiliation":[{"name":"Department of Perfusion, Ghent University Hospital , Ghent,","place":["Belgium"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Vandenheuvel","sequence":"additional","affiliation":[{"name":"Department of Cardiac Anaesthesia, Ghent University Hospital , Ghent,","place":["Belgium"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pascal","family":"Verdonck","sequence":"additional","affiliation":[{"name":"Department of Biomedical Engineering, Ghent University , Ghent,","place":["Belgium"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thierry","family":"Bov\u00e9","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery, Ghent University Hospital , Ghent,","place":["Belgium"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2025,5,29]]},"reference":[{"key":"2025063009211408100_ivaf127-B1","doi-asserted-by":"publisher","first-page":"48","DOI":"10.1093\/icvts\/ivaa052","article-title":"The impact of cardiopulmonary bypass management on outcome: a propensity matched comparison between minimally invasive and conventional valve surgery","volume":"31","author":"Vandewiele","year":"2020","journal-title":"Interact Cardiovasc Thorac Surg"},{"key":"2025063009211408100_ivaf127-B2","doi-asserted-by":"publisher","first-page":"655","DOI":"10.1111\/j.1525-1594.2004.07373.x","article-title":"Prediction of the clinical performance of adult arterial cannulas","volume":"28","author":"De Somer","year":"2004","journal-title":"Artif Organs"},{"key":"2025063009211408100_ivaf127-B3","doi-asserted-by":"publisher","first-page":"331","DOI":"10.1177\/0267659119885586","article-title":"Peripheral cannulae selection for veno-arterial extracorporeal life support: a paradox","volume":"35","author":"Ganushchak","year":"2020","journal-title":"Perfusion"},{"key":"2025063009211408100_ivaf127-B4","doi-asserted-by":"publisher","first-page":"566","DOI":"10.1111\/j.1525-1594.2008.00584.x","article-title":"Laboratory performance testing of venous cannulae during inlet obstruction","volume":"32","author":"Simons","year":"2008","journal-title":"Artif Organs"},{"year":"2003","author":"De Somer","key":"2025063009211408100_ivaf127-B5"},{"key":"2025063009211408100_ivaf127-B6","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1177\/0267659119830514","article-title":"Pressure and flow properties of cannulae for extracorporeal membrane oxygenation II: drainage (venous) cannulae","volume":"34","author":"Broman","year":"2019","journal-title":"Perfusion"},{"key":"2025063009211408100_ivaf127-B7","doi-asserted-by":"publisher","first-page":"571","DOI":"10.1080\/10543400701329422","article-title":"Agreement between methods of measurement with multiple observations per individual","volume":"17","author":"Bland","year":"2007","journal-title":"J Biopharm Stat"},{"key":"2025063009211408100_ivaf127-B8","doi-asserted-by":"publisher","first-page":"46","DOI":"10.1097\/MAT.0b013e318277a84f","article-title":"Prevention of caval collapse during venous drainage for CPB","volume":"59","author":"Abdel-Sayed","year":"2013","journal-title":"ASAIO"},{"key":"2025063009211408100_ivaf127-B9","doi-asserted-by":"publisher","first-page":"306","DOI":"10.1093\/ejcts\/ezt620","article-title":"Caval collapse during cardiopulmonary bypass: a reproducible bench model","volume":"46","author":"Li","year":"2014","journal-title":"Eur J Cardio-Thorac Surg"},{"key":"2025063009211408100_ivaf127-B10","doi-asserted-by":"publisher","first-page":"411","DOI":"10.1177\/0267659108089759","article-title":"New bench test for venous cannula performance assessment","volume":"22","author":"Abdel-Sayed","year":"2007","journal-title":"Perfusion"},{"key":"2025063009211408100_ivaf127-B11","doi-asserted-by":"publisher","first-page":"635","DOI":"10.1016\/j.ejcts.2008.05.037","article-title":"Routine use of self-expanding venous cannulas for cardiopulmonary bypass: benefits and pitfalls in 100 consecutive cases","volume":"34","author":"von Segesser","year":"2008","journal-title":"Eur J Cardio-Thorac Surg"},{"key":"2025063009211408100_ivaf127-B12","doi-asserted-by":"publisher","first-page":"491","DOI":"10.1177\/15569845221131534","article-title":"Single-center experience with a self-expandable venous cannula during minimally invasive cardiac surgery","volume":"17","author":"Van Praet","year":"2022","journal-title":"Innovations (Phila)"},{"key":"2025063009211408100_ivaf127-B13","doi-asserted-by":"publisher","first-page":"1221","DOI":"10.3390\/medicina59071221","article-title":"Virtually wall-less versus standard thin-wall venous cannula in the minimally invasive mitral valve surgery: single-center experience","volume":"59","author":"Ceresa","year":"2023","journal-title":"Medicina (Kaunas, Lithuania)"},{"key":"2025063009211408100_ivaf127-B14","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1051\/ject\/200234124","article-title":"Vacuum-assisted venous drainage: to air or not to air, that is the question. Has the bubble burst?","volume":"34","author":"Willcox","year":"2002","journal-title":"J ExtraCorpor Technol"},{"key":"2025063009211408100_ivaf127-B15","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1007\/s10047-005-0288-x","article-title":"Venous drainage method for cardiopulmonary bypass in single-access minimally invasive cardiac surgery: siphon and vacuum-assisted drainage","volume":"8","author":"Murai","year":"2005","journal-title":"Artif Organs"},{"key":"2025063009211408100_ivaf127-B16","doi-asserted-by":"publisher","first-page":"648","DOI":"10.1177\/0267659116651345","article-title":"VAVD vacuum may cause bubble transgression in membrane oxygenators","volume":"31","author":"Nygaard","year":"2016","journal-title":"Perfusion"},{"key":"2025063009211408100_ivaf127-B17","doi-asserted-by":"publisher","first-page":"262","DOI":"10.1055\/s-0031-1280019","article-title":"Hemolysis at different vacuum levels during vacuum-assisted venous drainage: a prospective randomized clinical trial","volume":"60","author":"Goksedef","year":"2012","journal-title":"Thorac Cardiovasc Surg"},{"key":"2025063009211408100_ivaf127-B18","doi-asserted-by":"publisher","first-page":"137","DOI":"10.1177\/026765919801300209","article-title":"Total extrathoracic cardiopulmonary support with kinetic assisted venous drainage: experience in 50 patients","volume":"13","author":"Toomasian","year":"1998","journal-title":"Perfusion"},{"key":"2025063009211408100_ivaf127-B19","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1051\/ject\/1998304160","article-title":"Assisted venous drainage, venous air, and gaseous microemboli transmission into the arterial line: an in vitro study","volume":"30","author":"Rider","year":"1998","journal-title":"J ExtraCorpor Technol"},{"key":"2025063009211408100_ivaf127-B20","doi-asserted-by":"publisher","first-page":"S49","DOI":"10.1191\/0267659104pf720oa","article-title":"Bubbles and bypass: an update","volume":"19","author":"Kurusz","year":"2004","journal-title":"Perfusion"},{"key":"2025063009211408100_ivaf127-B21","doi-asserted-by":"publisher","first-page":"1333","DOI":"10.1016\/S0003-4975(97)00098-2","article-title":"Extracorporeal membrane oxygenation using a centrifugal pump and a servo regulator to prevent negative inlet pressure","volume":"63","author":"Pedersen","year":"1997","journal-title":"Ann Thorac Surg"},{"key":"2025063009211408100_ivaf127-B22","doi-asserted-by":"publisher","first-page":"1285","DOI":"10.1016\/S0003-4975(99)00721-3","article-title":"Venous air in the bypass circuit: a source of arterial line emboli exacerbated by vacuum-assisted drainage","volume":"68","author":"Willcox","year":"1999","journal-title":"Ann Thorac Surg"},{"key":"2025063009211408100_ivaf127-B23","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1051\/ject\/2003353207","article-title":"Limitations using the vacuum-assist venous drainage technique during cardiopulmonary bypass procedures","volume":"35","author":"Jegger","year":"2003","journal-title":"J Extracorpor Technol"},{"key":"2025063009211408100_ivaf127-B24","doi-asserted-by":"publisher","first-page":"521","DOI":"10.1177\/0267659120936453","article-title":"Is there a \"safe\" suction pressure in the venous line of extracorporeal circulation system?","volume":"35","author":"Ganushchak","year":"2020","journal-title":"Perfusion"},{"key":"2025063009211408100_ivaf127-B25","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1093\/icvts\/ivaf002","article-title":"2024 EACTS\/EACTAIC\/EBCP guidelines on cardiopulmonary bypass in adult cardiac surgery","volume":"40","author":"Wahba","year":"2025","journal-title":"Interdiscip CardioVasc Thorac Surg"},{"key":"2025063009211408100_ivaf127-B26","doi-asserted-by":"publisher","first-page":"S606","DOI":"10.21037\/jtd.2018.03.101","article-title":"Cannulation for veno-venous extracorporeal membrane oxygenation","volume":"10","author":"Lindholm","year":"2018","journal-title":"J Thorac Dis"},{"key":"2025063009211408100_ivaf127-B27","doi-asserted-by":"publisher","first-page":"330","DOI":"10.1111\/aor.14421","article-title":"Numerical and experimental investigation of a lighthouse tip drainage cannula used in extracorporeal membrane oxygenation","volume":"47","author":"Fiusco","year":"2023","journal-title":"Artif Organs"},{"key":"2025063009211408100_ivaf127-B28","doi-asserted-by":"publisher","first-page":"854938","DOI":"10.1155\/2012\/854938","article-title":"The need of slanted side holes for venous cannulae","volume":"2012","author":"Park","year":"2012","journal-title":"Comput Math Methods Med"},{"key":"2025063009211408100_ivaf127-B29","doi-asserted-by":"publisher","first-page":"205","DOI":"10.1097\/MAT.0000000000001440","article-title":"Improved drainage cannula design to reduce thrombosis in veno-arterial extracorporeal membrane oxygenation","volume":"68","author":"Vatani","year":"2022","journal-title":"ASAIO J"},{"key":"2025063009211408100_ivaf127-B30","doi-asserted-by":"publisher","first-page":"154","DOI":"10.1111\/j.1525-1594.2007.00356.x","article-title":"An in vitro and in vivo study of the detection and reversal of venous collapse during extracorporeal life support","volume":"31","author":"Simons","year":"2007","journal-title":"Artif Organs"},{"key":"2025063009211408100_ivaf127-B31","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1111\/aor.12540","article-title":"Potential danger of pre-pump clamping on negative pressure-associated gaseous microemboli generation during extracorporeal life support\u2013an in vitro study","volume":"40","author":"Wang","year":"2016","journal-title":"Artif Organs"},{"key":"2025063009211408100_ivaf127-B32","doi-asserted-by":"publisher","first-page":"276","DOI":"10.1111\/j.1525-1594.2012.01560.x","article-title":"Hypovolemia in extracorporeal life support can lead to arterial gaseous microemboli","volume":"37","author":"Simons","year":"2013","journal-title":"Artif Organs"}],"container-title":["Interdisciplinary CardioVascular and Thoracic Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/icvts\/advance-article-pdf\/doi\/10.1093\/icvts\/ivaf127\/63401681\/ivaf127.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/icvts\/article-pdf\/40\/6\/ivaf127\/63401681\/ivaf127.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/icvts\/article-pdf\/40\/6\/ivaf127\/63401681\/ivaf127.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,30]],"date-time":"2025-06-30T13:21:18Z","timestamp":1751289678000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/icvts\/article\/doi\/10.1093\/icvts\/ivaf127\/8153091"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5,29]]},"references-count":32,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2025,6,4]]}},"URL":"https:\/\/doi.org\/10.1093\/icvts\/ivaf127","relation":{},"ISSN":["2753-670X"],"issn-type":[{"type":"electronic","value":"2753-670X"}],"subject":[],"published-other":{"date-parts":[[2025,6]]},"published":{"date-parts":[[2025,5,29]]},"article-number":"ivaf127"}}