{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,29]],"date-time":"2025-08-29T19:10:06Z","timestamp":1756494606622,"version":"3.44.0"},"reference-count":17,"publisher":"Oxford University Press (OUP)","issue":"8","license":[{"start":{"date-parts":[[2025,8,18]],"date-time":"2025-08-18T00:00:00Z","timestamp":1755475200000},"content-version":"vor","delay-in-days":17,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,8,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Objectives<\/jats:title>\n                  <jats:p>Data from the German Aortic Valve Registry (GARY) were analysed to determine whether there are differences between patients with and without chronic lung disease (CLD) undergoing transcatheter aortic valve implantation (TAVI) and surgical aortic valve replacement (SAVR) and whether TAVI or SAVR is more beneficial in patients with preexisting CLD.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>Follow-up data from GARY registry patients treated from 2014 to 2015 and from 2018 to 2019 were incorporated in the analysis. Demographic results for each of the 2 treatment modalities were evaluated, and patients with and without CLD were compared. In a second step, variables that would have influenced the treatment decision in CLD patients in direction of either SAVR or TAVI were accounted for in the adjusted analysis. This led to a subgroup of 1385 patients with CLD that was subjected to propensity score weighted analysis to compare outcomes of TAVI and SAVR.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>After exclusion, 11\u00a0457 SAVR patients and 2378 TAVI patients were analysed. CLD patients were sicker than patients without CLD, although the observed 30-day mortality was lower than expected by 3 risk scores. Accordingly, long-term survival in CLD patients was lower in both treatment groups than in patients without CLD. Thirty-day mortality was similar in the 2 treatment groups (SAVR 2.3%, TAVI 3.8%, P\u2009=\u2009.964) in spite of a possible selection bias in favour of SAVR. During a 5-year follow-up, survival after TAVI (44.6%) was significantly lower than after SAVR (56.7%), P\u2009=\u2009.029.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>Patients with CLD undergoing SAVR or TAVI are generally at higher risk for complications or death after the procedure than patients without CLD. After 5 years, patient-reported outcomes were similar in TAVI and in SAVR patients.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/icvts\/ivaf189","type":"journal-article","created":{"date-parts":[[2025,8,18]],"date-time":"2025-08-18T12:54:44Z","timestamp":1755521684000},"source":"Crossref","is-referenced-by-count":0,"title":["Short- and Long-Term Outcomes After Transcatheter or Surgical Aortic Valve Replacement in Patients With Chronic Lung Disease: An Analysis From the German Aortic Valve Registry"],"prefix":"10.1093","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4404-510X","authenticated-orcid":false,"given":"Andreas","family":"B\u00f6ning","sequence":"first","affiliation":[{"name":"Department of Cardiovascular Surgery, University Hospital Giessen , 35392 Giessen,","place":["Germany"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Umniye","family":"Balaban","sequence":"additional","affiliation":[{"name":"Goethe University Frankfurt, Institute of Biostatistics and Mathematical Modelling , Frankfurt,","place":["Germany"]},{"name":"German Center for Cardiovascular Research, DZHK (Deutsches Zentrum f\u00fcr Herz-Kreislaufforschung), Partner Site Rhine-Main , Frankfurt am Main,","place":["Germany"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eva","family":"Herrmann","sequence":"additional","affiliation":[{"name":"Goethe University Frankfurt, Institute of Biostatistics and Mathematical Modelling , Frankfurt,","place":["Germany"]},{"name":"German Center for Cardiovascular Research, DZHK (Deutsches Zentrum f\u00fcr Herz-Kreislaufforschung), Partner Site Rhine-Main , Frankfurt am Main,","place":["Germany"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andreas","family":"Beckmann","sequence":"additional","affiliation":[{"name":"Department for Cardiac Surgery, Heart Center Duisburg , Duisburg,","place":["Germany"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raffi","family":"Bekeredjian","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Robert-Bosch Hospital Stuttgart , Stuttgart,","place":["Germany"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9669-7372","authenticated-orcid":false,"given":"Sabine","family":"Bleiziffer","sequence":"additional","affiliation":[{"name":"Clinic for Thoracic and Cardiovascular Surgery, Herz-und Diabeteszentrum Bad Oeynhausen, Bad Oeynhausen ,","place":["Germany"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9508-3261","authenticated-orcid":false,"given":"Stephan","family":"Ensminger","sequence":"additional","affiliation":[{"name":"Department of Thoracic and Cardiovascular Surgery, University Hospital Schleswig-Holstein , L\u00fcbeck,","place":["Germany"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christian","family":"Frerker","sequence":"additional","affiliation":[{"name":"Department of Medicine, University Medical Center Schleswig-Holstein , L\u00fcbeck,","place":["Germany"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Helge","family":"M\u00f6llmann","sequence":"additional","affiliation":[{"name":"Medizinische Klinik I, St.-Johannes-Hospital Dortmund , Dortmund,","place":["Germany"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Walther","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery, Goethe University Hospital , Frankfurt,","place":["Germany"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Timm","family":"Bauer","sequence":"additional","affiliation":[{"name":"Sana Klinikum Offenbach, Department of Cardiology , 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