{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,24]],"date-time":"2026-01-24T18:47:28Z","timestamp":1769280448462,"version":"3.49.0"},"reference-count":5,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2025,12,24]],"date-time":"2025-12-24T00:00:00Z","timestamp":1766534400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["92259303"],"award-info":[{"award-number":["92259303"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82450112"],"award-info":[{"award-number":["82450112"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"CAMS Innovation Fund for Medical Sciences","award":["2021-I2M-5\u2013002"],"award-info":[{"award-number":["2021-I2M-5\u2013002"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,1,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To assess the application of preoperative indocyanine green (ICG) near-infrared (NIR) fluorescence imaging in video-assisted thoracoscopic surgery (VATS) for posterior mediastinal neurogenic tumors.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We present a case of a 66-year-old female with a T3-adjacent posterior mediastinal tumor. She received intravenous ICG (5 mg\/kg) 24 hours before surgery. Intraoperative NIR imaging was used to identify the tumor and nearby nerves during VATS.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>ICG fluorescence clearly delineated the tumor margins and visualized the adjacent sympathetic and intercostal nerves. This guided the complete resection of the tumor, which extended into the intervertebral foramen, with no postoperative complications. Pathology confirmed a schwannoma.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>ICG NIR imaging offers enhanced intraoperative visualization for complex posterior mediastinal tumors. It aids in distinguishing tumor from normal tissue and identifying key nerves, thereby facilitating complete resection while minimizing the risk of iatrogenic injury. This technique shows promise for managing \"dumbbell\" tumors via a minimally invasive approach.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Preoperative ICG injection is a useful adjunct in VATS for posterior mediastinal tumors, improving the delineation of tumor borders and neural structures to enhance surgical precision and safety.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/icvts\/ivaf211","type":"journal-article","created":{"date-parts":[[2025,12,23]],"date-time":"2025-12-23T12:53:00Z","timestamp":1766494380000},"source":"Crossref","is-referenced-by-count":0,"title":["Preoperative Intravenous Indocyanine Green Injection Demarcates Tumor Border and Adjacent Nerves in Surgical Resection of Posterior Mediastinal Neurogenic Tumors"],"prefix":"10.1093","volume":"41","author":[{"given":"Kongxu","family":"Dai","sequence":"first","affiliation":[{"name":"Department of Thoracic Surgery, Peking University People\u2019s Hospital , Beijing 100044,","place":["China"]},{"name":"Thoracic Oncology Institute, Peking University People\u2019s Hospital , Beijing 100044,","place":["China"]},{"name":"Research Unit of Intelligence Diagnosis and Treatment in Early Non-small Cell Lung Cancer, Chinese Academy of Medical Sciences, 2021RU002, Peking University People\u2019s Hospital , Beijing 100044,","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Feng","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, Peking University People\u2019s Hospital , Beijing 100044,","place":["China"]},{"name":"Thoracic Oncology Institute, Peking University People\u2019s Hospital , Beijing 100044,","place":["China"]},{"name":"Research Unit of Intelligence Diagnosis and Treatment in Early Non-small Cell Lung Cancer, Chinese Academy of Medical Sciences, 2021RU002, Peking University People\u2019s Hospital , Beijing 100044,","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yun","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, Peking University People\u2019s Hospital , Beijing 100044,","place":["China"]},{"name":"Thoracic Oncology Institute, Peking University People\u2019s Hospital , Beijing 100044,","place":["China"]},{"name":"Research Unit of Intelligence Diagnosis and Treatment in Early Non-small Cell Lung Cancer, Chinese Academy of Medical Sciences, 2021RU002, Peking University People\u2019s Hospital , Beijing 100044,","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5371-9295","authenticated-orcid":false,"given":"Jian","family":"Zhou","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, Peking University People\u2019s Hospital , Beijing 100044,","place":["China"]},{"name":"Thoracic Oncology Institute, Peking University People\u2019s Hospital , Beijing 100044,","place":["China"]},{"name":"Research Unit of Intelligence Diagnosis and Treatment in Early Non-small Cell Lung Cancer, Chinese Academy of Medical Sciences, 2021RU002, Peking University People\u2019s Hospital , Beijing 100044,","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2025,12,24]]},"reference":[{"key":"2026012304322913400_ivaf211-B1","doi-asserted-by":"publisher","first-page":"S97","DOI":"10.1097\/JTO.0000000000000292","article-title":"A modern definition of mediastinal compartments","volume":"9","author":"Carter","year":"2014","journal-title":"J Thorac Oncol"},{"key":"2026012304322913400_ivaf211-B2","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1016\/S0025-6196(25)38074-2","article-title":"Dumbbell neurogenic tumors of the mediastinum. Diagnosis and management","volume":"53","author":"Akwari","year":"1978","journal-title":"Mayo Clin Proc"},{"key":"2026012304322913400_ivaf211-B3","doi-asserted-by":"publisher","first-page":"304","DOI":"10.7150\/thno.22369","article-title":"Near-infrared intraoperative imaging of thoracic sympathetic nerves: from preclinical study to clinical trial","volume":"8","author":"He","year":"2018","journal-title":"Theranostics"},{"key":"2026012304322913400_ivaf211-B4","doi-asserted-by":"publisher","first-page":"749","DOI":"10.1055\/s-0040-1712499","article-title":"Primary intrathoracic neurogenic tumors: clinical, pathological, and long-term outcomes","volume":"69","author":"Galetta","year":"2021","journal-title":"Thorac Cardiovasc Surg"},{"key":"2026012304322913400_ivaf211-B5","doi-asserted-by":"publisher","first-page":"2767","DOI":"10.1111\/1759-7714.14122","article-title":"Combined minimally invasive resection of thoracic neurogenic dumbbell tumors: a European case series","volume":"12","author":"Harrison","year":"2021","journal-title":"Thorac Cancer"}],"container-title":["Interdisciplinary CardioVascular and Thoracic Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/icvts\/advance-article-pdf\/doi\/10.1093\/icvts\/ivaf211\/66125764\/ivaf211.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/icvts\/article-pdf\/41\/1\/ivaf211\/66125764\/ivaf211.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/icvts\/article-pdf\/41\/1\/ivaf211\/66125764\/ivaf211.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,23]],"date-time":"2026-01-23T09:32:31Z","timestamp":1769160751000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/icvts\/article\/doi\/10.1093\/icvts\/ivaf211\/8404455"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12,24]]},"references-count":5,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,1,6]]}},"URL":"https:\/\/doi.org\/10.1093\/icvts\/ivaf211","relation":{},"ISSN":["2753-670X"],"issn-type":[{"value":"2753-670X","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2026,1]]},"published":{"date-parts":[[2025,12,24]]},"article-number":"ivaf211"}}