{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,23]],"date-time":"2026-01-23T18:28:17Z","timestamp":1769192897694,"version":"3.49.0"},"reference-count":39,"publisher":"Oxford University Press (OUP)","issue":"10","license":[{"start":{"date-parts":[[2025,9,27]],"date-time":"2025-09-27T00:00:00Z","timestamp":1758931200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Open Access Publication Fund of UKE - Universit\u00e4tsklinikum Hamburg-Eppendorf"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,10,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Objectives<\/jats:title>\n                  <jats:p>Concomitant atrial fibrillation ablation is a well-established procedure in patients undergoing mitral valve (MV) surgery. However, data concerning the long-term outcomes of cryoablation performed during totally endoscopic MV surgery remain limited. Furthermore, different lesion sets and energy sources used in endoscopic approach may result in varying outcomes. We therefore, analysed rhythm outcome in patients undergoing left-sided cryoablation during totally endoscopic MV surgery.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>Patients, who underwent totally endoscopic MV surgery with concomitant left-sided cryoablation between 2016 and 2023 at our centre were included in the study. The retrospective data analysis was based on 24-h Holter monitor follow-up data.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>A total of 123 patients were included in the study. No complications related to the ablation procedure were observed. The median follow-up period was 36.0 (interquartile range: 17-60)\u2009months. During this period, 34 episodes of atrial fibrillation recurrence were documented, corresponding to a recurrence rate of 8.43 per 100 patient-years (95% confidence interval: 5.90-11.73). The estimated freedom from AF at 1, 3, and 5\u2009years were 96.6%, 86.3%, and 69.4% respectively. Type of atrial fibrillation (P\u2009=\u2009.004; hazard ratio [HR]: 2.521; 95% confidence interval [CI]: 1.347-4.716) and left atrial volume (P\u2009=\u2009.003; HR: 1.010; 95% CI: 1.003-1.016) were identified as predictors for atrial fibrillation recurrence.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>Concomitant left-sided cryoablation during totally endoscopic MV surgery is a safe and effective procedure for atrial fibrillation treatment. The encouraging long-term outcomes support the consideration of this approach in totally endoscopic mitral surgery.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/icvts\/ivaf217","type":"journal-article","created":{"date-parts":[[2025,9,27]],"date-time":"2025-09-27T15:36:39Z","timestamp":1758987399000},"source":"Crossref","is-referenced-by-count":1,"title":["Long-Term Outcomes of Concomitant Left-Sided Cryoablation During Totally Endoscopic Mitral Valve Surgery"],"prefix":"10.1093","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5004-6929","authenticated-orcid":false,"given":"Ilia","family":"Bazhanov","sequence":"first","affiliation":[{"name":"Department of Cardiovascular Surgery, University Heart and Vascular Center Hamburg, University Medical-Center Hamburg-Eppendorf , Hamburg 20246,","place":["Germany"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3415-3385","authenticated-orcid":false,"given":"Johannes","family":"Petersen","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, University Heart and Vascular Center Hamburg, University Medical-Center Hamburg-Eppendorf , Hamburg 20246,","place":["Germany"]},{"name":"DZHK (German Centre for Cardiovascular Research), Partner Site Hamburg\/Kiel\/L\u00fcbeck , Hamburg 20246,","place":["Germany"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yalin","family":"Yildirim","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, University Heart and Vascular Center Hamburg, University Medical-Center Hamburg-Eppendorf , Hamburg 20246,","place":["Germany"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7418-1815","authenticated-orcid":false,"given":"Jonas","family":"Pausch","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, University Heart and Vascular Center Hamburg, University Medical-Center Hamburg-Eppendorf , Hamburg 20246,","place":["Germany"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Evaldas","family":"Girdauskas","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, University Hospital Augsburg , Augsburg 86156,","place":["Germany"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yousuf","family":"Al Assar","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, University Heart and Vascular Center Hamburg, University Medical-Center Hamburg-Eppendorf , Hamburg 20246,","place":["Germany"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hermann","family":"Reichenspurner","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, University Heart and Vascular Center Hamburg, University Medical-Center Hamburg-Eppendorf , Hamburg 20246,","place":["Germany"]},{"name":"DZHK (German Centre for Cardiovascular Research), Partner Site Hamburg\/Kiel\/L\u00fcbeck , Hamburg 20246,","place":["Germany"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8747-166X","authenticated-orcid":false,"given":"Simon","family":"Pecha","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, University Heart and Vascular Center Hamburg, University Medical-Center Hamburg-Eppendorf , Hamburg 20246,","place":["Germany"]},{"name":"DZHK (German Centre for Cardiovascular Research), Partner Site Hamburg\/Kiel\/L\u00fcbeck , Hamburg 20246,","place":["Germany"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2025,9,27]]},"reference":[{"key":"2025101011021574300_ivaf217-B1","doi-asserted-by":"crossref","first-page":"213","DOI":"10.2147\/CLEP.S47385","article-title":"Epidemiology of atrial fibrillation: European perspective","volume":"6","author":"Zoni-Berisso","year":"2014","journal-title":"Clin Epidemiol"},{"key":"2025101011021574300_ivaf217-B2","doi-asserted-by":"crossref","first-page":"2746","DOI":"10.1093\/eurheartj\/eht280","article-title":"Projections on the number of individuals with atrial fibrillation in the european union, from 2000 to 2060","volume":"34","author":"Krijthe","year":"2013","journal-title":"Eur Heart J"},{"key":"2025101011021574300_ivaf217-B3","doi-asserted-by":"crossref","first-page":"E93","DOI":"10.1161\/CIR.0000000000001123","article-title":"Heart disease and stroke statistics - 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