{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T09:35:52Z","timestamp":1762853752096,"version":"build-2065373602"},"reference-count":15,"publisher":"Oxford University Press (OUP)","issue":"11","license":[{"start":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T00:00:00Z","timestamp":1761091200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,11,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>The mortality rate of ventricular septal defect (VSD) following acute myocardial infarction remains high. Mechanical circulatory support devices have been shown to facilitate delayed surgery and improve postoperative survival, although clear guidelines for device selection are lacking.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This study presents a retrospective cohort analysis of 18 patients with post-infarction VSD treated with microaxial flow pump (mAFP) from March 2017 to November 2024. Patients were divided into 2 groups: the percutaneous group utilized Impella 2.5 or CP (Abiomed, Danvers, MA, USA) and the axillary access group (Impella 5.0 or 5.5). Their clinical outcomes and early to midterm survival rates were analysed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The survival discharge rate was 31% (4 in 13 patients) in the percutaneous group and 100% (5 patients) in the axillary access group, with a significant difference (P\u2009=\u2009.029). Seven patients who were initially managed with percutaneous mAFP and later required the addition of extracorporeal membrane oxygenation all died perioperatively. The 100-day Kaplan-Meier analysis showed a significant improvement in survival rates in the axillary access group compared to the percutaneous group (log-rank, P\u2009=\u2009.020).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>These findings illustrate variation in surgical timing and device selection and suggest that the early use of an axillary access mAFP may warrant further investigation in post-myocardial infarction VSD patients.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/icvts\/ivaf253","type":"journal-article","created":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T11:25:02Z","timestamp":1760959502000},"source":"Crossref","is-referenced-by-count":0,"title":["Impact of Initial Axillary Microaxial Flow Pump on Post-Myocardial Infarction Ventricular Septal Defect Management"],"prefix":"10.1093","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-4345-9837","authenticated-orcid":false,"given":"Kenta","family":"Murakami","sequence":"first","affiliation":[{"name":"Department of Clinical Engineering, Nagoya Tokushukai General Hospital , Kasugai Aichi 487-0016,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9828-0300","authenticated-orcid":false,"given":"Shin","family":"Hasegawa","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Nagoya Tokushukai General Hospital , Kasugai Aichi 487-0016,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akinao","family":"Miki","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Nagoya Tokushukai General Hospital , Kasugai Aichi 487-0016,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hirotaka","family":"Yamauchi","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Nagoya Tokushukai General Hospital , Kasugai Aichi 487-0016,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1016-0764","authenticated-orcid":false,"given":"Akimitsu","family":"Tanaka","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Nagoya Tokushukai General Hospital , Kasugai Aichi 487-0016,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takeki","family":"Ohashi","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Nagoya Tokushukai General Hospital , Kasugai Aichi 487-0016,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Soh","family":"Hosoba","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Nagoya Tokushukai General Hospital , Kasugai Aichi 487-0016,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2025,10,22]]},"reference":[{"key":"2025111104320079400_ivaf253-B1","first-page":"ivae137","article-title":"Preoperative Impella therapy in patients with ventricular septal rupture and cardiogenic shock: hemodynamic and organ function outcomes","volume":"39","author":"Shibasaki","year":"2024","journal-title":"Interdiscip Cardiovasc Thorac Surg."},{"key":"2025111104320079400_ivaf253-B2","doi-asserted-by":"crossref","first-page":"e491","DOI":"10.1097\/MAT.0000000000002060","article-title":"Impella for the management of ventricular septal defect complicating acute myocardial infarction: a European multicenter 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Thorac Surg."},{"key":"2025111104320079400_ivaf253-B9","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1016\/S1010-7940(00)00482-6","article-title":"Post infarction ventricular septal defect\u2014can we do better?","volume":"18","author":"Deja","year":"2000","journal-title":"Eur J Cardiothorac Surg."},{"key":"2025111104320079400_ivaf253-B10","doi-asserted-by":"crossref","first-page":"1382","DOI":"10.1056\/NEJMoa2312572","article-title":"Microaxial flow pump or standard care in infarct-related cardiogenic shock","volume":"390","author":"M\u00f8ller","year":"2024","journal-title":"N Engl J Med"},{"key":"2025111104320079400_ivaf253-B11","first-page":"115","article-title":"Usefulness of impella support in different clinical settings in cardiogenic shock","volume":"19","author":"Barrionuevo-S\u00e1nchez","year":"2022","journal-title":"J Geriatr Cardiol"},{"key":"2025111104320079400_ivaf253-B12","first-page":"zuae132","article-title":"Device-related adverse events and flow capacity 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