{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,2]],"date-time":"2026-03-02T19:56:06Z","timestamp":1772481366960,"version":"3.50.1"},"reference-count":22,"publisher":"Oxford University Press (OUP)","issue":"12","license":[{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,12,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To compare postoperative outcomes between hydrogel-coated chest drains (HCDs) and conventional non-coated drains (NCDs) in patients undergoing general thoracic surgery, using a propensity score-matched analysis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This retrospective multi-institutional study included adult patients who underwent thoracic surgery across 4 European centres between February and September 2022. Patients were grouped according to drain type (HCD vs NCD), and a propensity score-matched analysis was performed to account for 16 preoperative and intraoperative covariates. The primary outcome was length of postoperative hospital stay (LOS). Secondary outcomes included in-hospital complications, intensive care unit (ICU) admission, chest drain reinsertion, readmission, duration of drainage, and in-hospital mortality. Subgroup analysis was performed in patients undergoing anatomical lung resections.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 773 patients were included (HCD n\u2009=\u2009362; NCD n\u2009=\u2009411). After matching, 724 patients were analysed. HCD use was associated with a significantly shorter LOS (average treatment effect of the treated population \u22121.87 days; 95% CI \u22123.04 to \u22120.695; P\u2009=\u2009.002), lower odds of ICU admission (odds ratio [OR] 0.29; 95% CI 0.16-0.53; P\u2009&amp;lt;\u2009.001), and lower in-hospital complication rates (OR 0.38; 95% CI 0.26-0.55; P\u2009&amp;lt;\u2009.001). Rates of pneumonia (5.2% vs 13.4%; P\u2009=\u2009.001), atrial fibrillation (2.2% vs 9.0%; P\u2009&amp;lt;\u2009.001), and retained pleural effusion (0.8% vs 3.6%; P\u2009=\u2009.015) were significantly lower in the HCD group. There were no significant differences in drain duration, readmission, or mortality. In the anatomical resection subgroup, HCDs were similarly associated with reduced LOS and complications.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Hydrogel-coated drains are associated with fewer postoperative complications and shorter hospital stay compared to conventional drains, particularly in anatomical lung resections. These findings support further prospective evaluation to define the role of HCDs in routine thoracic surgical practice.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/icvts\/ivaf290","type":"journal-article","created":{"date-parts":[[2025,11,29]],"date-time":"2025-11-29T12:59:28Z","timestamp":1764421168000},"source":"Crossref","is-referenced-by-count":0,"title":["Impact of Hydrogel-Coated Chest Drains on Outcomes in Thoracic Surgery"],"prefix":"10.1093","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9170-8618","authenticated-orcid":false,"given":"Akshay J","family":"Patel","sequence":"first","affiliation":[{"name":"Division of Thoracic Surgery, Toronto General Hospital , Toronto, ON M5G 2C4,","place":["Canada"]},{"name":"Institute of Immunology and Immunotherapy, University of Birmingham, Edgbaston , Birmingham B15 2TT,","place":["United Kingdom"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefano","family":"Cafarotti","sequence":"additional","affiliation":[{"name":"Thoracic Surgery Department, Ente Ospedaliero Cantonale , Bellinzona,","place":["Switzerland"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Kiefer","sequence":"additional","affiliation":[{"name":"Thoracic Surgery Department, Lungezentrum Bodensee , Konstanz,","place":["Germany"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesco","family":"Leo","sequence":"additional","affiliation":[{"name":"Thoracic Surgery Department, Ospedale S. Luigi Gonzaga , Orbassano,","place":["Italy"]},{"name":"Department of Oncology, University of Turin , Turin,","place":["Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Puiyee Sophia","family":"Chan","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, Guy\u2019s Hospital, Guy\u2019s and St Thomas NHS Foundation Trust , London SE1 9RT,","place":["United Kingdom"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Federico","family":"Femia","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, Guy\u2019s Hospital, Guy\u2019s and St Thomas NHS Foundation Trust , London SE1 9RT,","place":["United Kingdom"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adele","family":"Tessitore","sequence":"additional","affiliation":[{"name":"Thoracic Surgery Department, Ente Ospedaliero Cantonale , Bellinzona,","place":["Switzerland"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miriam","family":"Patella","sequence":"additional","affiliation":[{"name":"Thoracic Surgery Department, Ente Ospedaliero Cantonale , Bellinzona,","place":["Switzerland"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Simona","family":"Sobrero","sequence":"additional","affiliation":[{"name":"Thoracic Surgery Department, Ospedale S. 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