{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,15]],"date-time":"2025-12-15T21:18:32Z","timestamp":1765833512295,"version":"3.48.0"},"reference-count":21,"publisher":"Oxford University Press (OUP)","issue":"12","license":[{"start":{"date-parts":[[2025,12,4]],"date-time":"2025-12-04T00:00:00Z","timestamp":1764806400000},"content-version":"vor","delay-in-days":3,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000274","name":"British Heart Foundation","doi-asserted-by":"publisher","award":["SP\/19\/7\/34810"],"award-info":[{"award-number":["SP\/19\/7\/34810"]}],"id":[{"id":"10.13039\/501100000274","id-type":"DOI","asserted-by":"publisher"}]},{"name":"NIHR Biomedical Research Centre at University Hospitals Bristol"},{"name":"Weston NHS Foundation Trust"},{"DOI":"10.13039\/501100000883","name":"University of Bristol","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000883","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,12,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>Chronic kidney disease requiring dialysis significantly increases the risks of coronary artery disease. However, there is limited data on this high-risk patient population requiring coronary artery bypass grafting. Using a UK national registry, we investigated the impact of preoperative dialysis on in-hospital mortality and early morbidity in patients undergoing coronary artery bypass graft (CABG).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A retrospective analysis of National Adult Cardiac Surgery Audit data between January 1996, 2, and March 31, 2019, identified patients who underwent first-time isolated CABG. Propensity matching was performed to balance the baseline characteristics between dialysis and non-dialysis patients, yielding 633 matched pairs. We evaluated trends in CABG among dialysis patients and EuroSCORE 2 performance in predicting in-hospital mortality (calibration, discrimination, and clinical utility).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>There was a steep increase in CABG operations in dialysis patients after 2011. EuroSCORE 2 showed poor calibration, discrimination, and minimal clinical benefit in predicting mortality in dialysis cases. Dialysis patients exhibited a significantly higher in-hospital mortality rate (7.9% vs 2.1%, P\u2009&amp;lt;\u2009.001) than non-dialysis patients. The dialysis patients had longer median hospital stays (12 vs 9 days, P\u2009&amp;lt;\u2009.001) and a higher rate of return to the theatre for bleeding (5.5% vs 2.7%, P\u2009=\u2009.034). We found no difference in postoperative neurological deficit rates between the 2 cohorts. The odds ratio of in-hospital mortality for the dialysis vs non-dialysis patients was 4.62, P\u2009&amp;lt;\u2009.001, 95% (CI: 2.54-8.4). Significant predictors of mortality in the dialysis CABG cohort included advanced age (OR: 2.48), New York Heart Association class IV (OR: 3.06), and pulmonary hypertension (OR: 11.91).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>There has been an overall increase in coronary artery bypass operations performed in renal dialysis-dependent patients in the UK. Preoperative chronic dialysis is associated with considerable in-hospital mortality, return to theatre for bleeding and prolonged hospital stay. EuroSCORE 2 has poor predictive performance in this patient cohort.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/icvts\/ivaf291","type":"journal-article","created":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T12:36:54Z","timestamp":1764592614000},"source":"Crossref","is-referenced-by-count":0,"title":["Coronary Artery Bypass Surgery in Patients on Dialysis: In-Hospital Outcomes from UK Registry Analysis"],"prefix":"10.1093","volume":"40","author":[{"given":"Muhammed A","family":"Mashat","sequence":"first","affiliation":[{"name":"Bristol Heart Institute, University of Bristol , Bristol, BS2 8ED,","place":["UK"]},{"name":"King Abdulaziz University , Jeddah, 21589,","place":["Saudi Arabia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1953-0063","authenticated-orcid":false,"given":"Tim","family":"Dong","sequence":"additional","affiliation":[{"name":"Bristol Heart Institute, University of Bristol , Bristol, BS2 8ED,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2346-1259","authenticated-orcid":false,"given":"Rahul","family":"Kota","sequence":"additional","affiliation":[{"name":"Bristol Heart Institute, University of Bristol , Bristol, BS2 8ED,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ettorino","family":"Di Tommaso","sequence":"additional","affiliation":[{"name":"Bristol Heart Institute, University of Bristol , Bristol, BS2 8ED,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-8984-4473","authenticated-orcid":false,"given":"Pradeep","family":"Narayan","sequence":"additional","affiliation":[{"name":"Bristol Heart Institute, University of Bristol , Bristol, BS2 8ED,","place":["UK"]},{"name":"Department of Cardiac Surgery, Rabindranath Tagore International Institute of Cardiac Sciences, Narayana Health , Kolkata, 700099,","place":["India"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Charles","family":"Tan","sequence":"additional","affiliation":[{"name":"Bristol Heart Institute, University of Bristol , Bristol, BS2 8ED,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cha","family":"Rajakaruna","sequence":"additional","affiliation":[{"name":"Bristol Heart Institute, University of Bristol , Bristol, BS2 8ED,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eltayeb","family":"Mohamed Ahmed","sequence":"additional","affiliation":[{"name":"Bristol Heart Institute, University of Bristol , Bristol, BS2 8ED,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5573-7080","authenticated-orcid":false,"given":"Gianni D","family":"Angelini","sequence":"additional","affiliation":[{"name":"Bristol Heart Institute, University of Bristol , Bristol, BS2 8ED,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6759-7719","authenticated-orcid":false,"given":"Daniel P","family":"Fudulu","sequence":"additional","affiliation":[{"name":"Bristol Heart Institute, University of Bristol , Bristol, BS2 8ED,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2025,12,3]]},"reference":[{"author":"WHO","key":"2025121516164284600_ivaf291-B1"},{"key":"2025121516164284600_ivaf291-B2","doi-asserted-by":"crossref","first-page":"1157","DOI":"10.1161\/CIRCULATIONAHA.120.050686","article-title":"Cardiovascular disease in chronic kidney disease: pathophysiological insights and therapeutic options","volume":"143","author":"Jankowski","year":"2021","journal-title":"Circulation"},{"year":"2023","author":"Registry 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