{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,17]],"date-time":"2026-02-17T13:25:23Z","timestamp":1771334723870,"version":"3.50.1"},"reference-count":18,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T00:00:00Z","timestamp":1770681600000},"content-version":"vor","delay-in-days":9,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,2,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>Sex differences in outcomes after transcatheter aortic valve implantation (TAVI) remain incompletely understood. Earlier studies described a \u201csex paradox,\u201d with women experiencing more procedural complications but similar or superior survival compared with men. However, most data derive from earlier device generations, and contemporary evidence is limited.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We retrospectively analysed all patients with severe aortic stenosis who underwent TAVI at the University Hospital of Angers between January 2012 and December 2023. Clinical and procedural characteristics were collected from a dedicated database. Propensity-score matching (1:1) was performed to account for baseline differences. The primary end-point was 30-day mortality.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 2718 patients underwent TAVI, of whom 49.1% were women. Women were older but had fewer comorbidities than men. After matching (1320 pairs), procedural duration was similar, but women more often required alternative access and received self-expandable valves. Thirty-day mortality did not differ between sexes, but all-cause mortality was significantly higher in men (P\u2009&amp;lt;\u2009.01). Women had a greater incidence of postoperative stroke, particularly in low-risk patients, whereas men had higher rates of acute renal failure and pacemaker implantation. The survival probability was higher for women in overall population and in low- and intermediate-risk patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>In this large, contemporary cohort, women experienced more strokes, whereas men had higher all-cause mortality and conduction-related complications. These findings underscore persistent sex-specific differences in TAVI outcomes and highlight the need for tailored procedural strategies.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/icvts\/ivag034","type":"journal-article","created":{"date-parts":[[2026,2,4]],"date-time":"2026-02-04T12:49:01Z","timestamp":1770209341000},"source":"Crossref","is-referenced-by-count":0,"title":["Sex-Related Differences After Transcatheter Aortic Valve Implantation: A Retrospective Propensity-Matched Cohort"],"prefix":"10.1093","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5433-2607","authenticated-orcid":false,"given":"Maroua","family":"Eid","sequence":"first","affiliation":[{"name":"University Hospital of Angers Department of Cardiac Surgery, , 4 rue Larrey , Angers 49933,","place":["France"]},{"name":"University Hospital of Angers Mitovasc Institute INSERM U1083 UMR-CNRS 6214, , 3 rue Roger Amsler , Angers 49055,","place":["France"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9195-1375","authenticated-orcid":false,"given":"Fr\u00e9d\u00e9ric","family":"Pinaud","sequence":"additional","affiliation":[{"name":"University Hospital of Angers Department of Cardiac Surgery, , 4 rue Larrey , Angers 49933,","place":["France"]},{"name":"University Hospital of Angers Mitovasc Institute INSERM U1083 UMR-CNRS 6214, , 3 rue Roger Amsler , Angers 49055,","place":["France"]},{"name":"University Hospital of Angers Department of Medico-Surgical Heart Valve Disease, , 4 rue Larrey , Angers 49933,","place":["France"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3065-9247","authenticated-orcid":false,"given":"Simon Dang","family":"Van","sequence":"additional","affiliation":[{"name":"University Hospital of Angers Department of Cardiac Surgery, , 4 rue Larrey , Angers 49933,","place":["France"]},{"name":"University Hospital of Angers Department of Medico-Surgical Heart Valve Disease, , 4 rue Larrey , Angers 49933,","place":["France"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8626-0011","authenticated-orcid":false,"given":"Antoine","family":"Ducroix","sequence":"additional","affiliation":[{"name":"University Hospital of Angers Department of Cardiac Surgery, , 4 rue Larrey , Angers 49933,","place":["France"]},{"name":"University Hospital of Angers Mitovasc Institute INSERM U1083 UMR-CNRS 6214, , 3 rue Roger Amsler , Angers 49055,","place":["France"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4276-7755","authenticated-orcid":false,"given":"Audrey","family":"Camarzana","sequence":"additional","affiliation":[{"name":"University Hospital of Angers Department of Medico-Surgical Heart Valve Disease, , 4 rue Larrey , Angers 49933,","place":["France"]},{"name":"University Hospital of Angers Department of Cardiology, , 4 rue Larrey , Angers 49933,","place":["France"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1293-1120","authenticated-orcid":false,"given":"Emmanuel","family":"Rineau","sequence":"additional","affiliation":[{"name":"University Hospital of Angers Mitovasc Institute INSERM U1083 UMR-CNRS 6214, , 3 rue Roger Amsler , Angers 49055,","place":["France"]},{"name":"University Hospital of Angers Department of Anesthesiology, , 4 rue Larrey , Angers 49933,","place":["France"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emmanuelle","family":"Longeau","sequence":"additional","affiliation":[{"name":"University Hospital of Angers Department of Anesthesiology, , 4 rue Larrey , Angers 49933,","place":["France"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4733-8346","authenticated-orcid":false,"given":"Wissam","family":"Abi-Khalil","sequence":"additional","affiliation":[{"name":"University Hospital of Angers Department of Medico-Surgical Heart Valve Disease, , 4 rue Larrey , Angers 49933,","place":["France"]},{"name":"University Hospital of Angers Department of Anesthesiology, , 4 rue Larrey , Angers 49933,","place":["France"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patrice","family":"Binuani","sequence":"additional","affiliation":[{"name":"University Hospital of Angers Department of Cardiac Surgery, , 4 rue Larrey , Angers 49933,","place":["France"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4176-3739","authenticated-orcid":false,"given":"Christophe","family":"Baufreton","sequence":"additional","affiliation":[{"name":"University Hospital of Angers Department of Cardiac Surgery, , 4 rue Larrey , Angers 49933,","place":["France"]},{"name":"University Hospital of Angers Mitovasc Institute INSERM U1083 UMR-CNRS 6214, , 3 rue Roger Amsler , Angers 49055,","place":["France"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fr\u00e9d\u00e9ric","family":"Rouleau","sequence":"additional","affiliation":[{"name":"University Hospital of Angers Department of Medico-Surgical Heart Valve Disease, , 4 rue Larrey , Angers 49933,","place":["France"]},{"name":"University Hospital of Angers Department of Cardiology, , 4 rue Larrey , Angers 49933,","place":["France"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9191-9095","authenticated-orcid":false,"given":"Olivier","family":"Fouquet","sequence":"additional","affiliation":[{"name":"University Hospital of Angers Department of Cardiac Surgery, , 4 rue Larrey , Angers 49933,","place":["France"]},{"name":"University Hospital of 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