{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T21:29:42Z","timestamp":1772141382453,"version":"3.50.1"},"reference-count":29,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T00:00:00Z","timestamp":1770768000000},"content-version":"vor","delay-in-days":10,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,2,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To determine whether CT within 6\u2009months after total arch replacement (TAR) with a frozen elephant trunk (FET) for chronic aortic dissection predicts mid-term outcomes and informs the timing of distal treatment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We analysed 56 consecutive patients who underwent TAR with FET at 2 centres (2009-2022) and had evaluable 6-month postoperative CT. Early remodelling was defined as the change from baseline to 6\u2009months in the maximal outer-to-outer diameter of the proximal descending thoracic aorta at Level A (Ishimaru zone 3, 20\u2009mm distal to the left subclavian artery, measured on centreline-orthogonal reconstructions). Patients were classified as early positive remodelling (EPR; no increase or a decrease) or early negative remodelling (ENR; \u22651-mm increase). Prespecified outcomes were distal aortic reintervention, distal stent graft-induced new entry (dSINE), and overall survival.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Mean follow-up was 5.4\u2009years (standard deviation 3.7). Distal reintervention was required in 36\/56 patients (64%). At 5\u2009years, freedom from distal reintervention was higher with EPR than with ENR (44.6% vs 6.2%; P\u2009=\u2009.003). dSINE occurred in 26\/56 patients (46.4%); 5-year dSINE-free survival was 65.1% (95% CI, 39.6-81.9) with EPR versus 18.2% (95% CI 5.9-35.2) with ENR (P\u2009=\u2009.008). Overall, 5-year survival for the cohort was 80.0% (95% CI 64.7-89.2). Among ENR patients, 5-year survival was 0% with conservative management versus 40.5% with distal intervention (P\u2009&amp;lt;\u2009.001); within EPR, 5-year survival was 65.9% with conservative management versus 85.7% with reintervention (P\u2009=\u2009.210).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>A 6-month CT provides simple, actionable risk stratification after TAR with FET for chronic aortic dissection. Absence of EPR identifies a high-risk subgroup (ENR) that warrants closer surveillance and timely distal intervention, optimizing follow-up intensity and treatment timing.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/icvts\/ivag046","type":"journal-article","created":{"date-parts":[[2026,2,5]],"date-time":"2026-02-05T12:39:06Z","timestamp":1770295146000},"source":"Crossref","is-referenced-by-count":0,"title":["Do Early Aortic Remodelling Patterns at 6\u2009Months Predict Mid-Term Outcomes After Frozen Elephant Trunk for Chronic Aortic Dissection?"],"prefix":"10.1093","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7783-9304","authenticated-orcid":false,"given":"Sho","family":"Akita","sequence":"first","affiliation":[{"name":"Department of Cardiac Surgery, Nagoya University Graduate School of Medicine , Nagoya, Aichi 466-8560,","place":["Japan"]},{"name":"Department of Cardiovascular Surgery, Yokkaichi Municipal Hospital , Yokkaichi, Mie, 510-8567 ,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6405-8752","authenticated-orcid":false,"given":"Yoshiyuki","family":"Tokuda","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery, Nagoya University Graduate School of Medicine , Nagoya, Aichi 466-8560,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akinori","family":"Tamenishi","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Yokkaichi Municipal Hospital , Yokkaichi, Mie, 510-8567 ,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasumoto","family":"Matsumura","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Yokkaichi Municipal Hospital , Yokkaichi, Mie, 510-8567 ,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akitaka","family":"Hayakawa","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Yokkaichi Municipal Hospital , Yokkaichi, Mie, 510-8567 ,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9740-2142","authenticated-orcid":false,"given":"Masato","family":"Mutsuga","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery, Nagoya University Graduate School of Medicine , Nagoya, Aichi 466-8560,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2026,2,10]]},"reference":[{"key":"2026022615511500000_ivag046-B1","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1093\/ejcts\/ezv045","article-title":"Aortic remodelling in aortic dissection after frozen elephant 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