{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,13]],"date-time":"2026-04-13T02:49:49Z","timestamp":1776048589145,"version":"3.50.1"},"reference-count":39,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2026,3,25]],"date-time":"2026-03-25T00:00:00Z","timestamp":1774396800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,4,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To assess short-term outcomes of coronary artery bypass grafting (CABG) with adjunct coronary endarterectomy (CE) compared with isolated bypass grafting, and to synthesize available confounder-adjusted effect estimates.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We conducted a systematic review and meta-analysis following PRISMA guidelines. MEDLINE, Embase, and CENTRAL were searched from January 2000 to June 2025. Eligible studies compared adult patients undergoing CABG with CE versus isolated CABG. Two reviewers independently screened studies, extracted data, and assessed quality. Random-effects meta-analysis was performed. The primary outcome was 30-day or in-hospital mortality.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Sixteen studies (119\u2009458 patients) were included. CABG with CE was associated with higher mortality (RR 1.84, 95% CI 1.65-2.04). Pooling adjusted odds ratios from 3 studies yielded OR 1.76 (95% CI 1.55-2.00), with 2 of 3 individual estimates not reaching significance. Secondary outcomes showed increased risks of perioperative myocardial infarction (RR 1.99, 95% CI 1.29-3.07), stroke (RR 1.37, 95% CI 1.08-1.75), renal failure (RR 1.62, 95% CI 1.44-1.82), and intra-aortic balloon pump use (RR 1.96, 95% CI 1.41-2.70). Sensitivity analyses confirmed consistency across all the subgroups.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>CABG with CE is associated with higher short-term mortality and morbidity compared with isolated bypass grafting; however, confounder-adjusted analyses suggest this excess risk is partly attributable to greater baseline disease severity rather than an independent procedural effect. The scarcity of data and absence of randomized evidence preclude definitive causal conclusions. These findings provide benchmarking data for counselling when endarterectomy is necessary to achieve complete revascularization.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/icvts\/ivag091","type":"journal-article","created":{"date-parts":[[2026,3,24]],"date-time":"2026-03-24T12:36:23Z","timestamp":1774355783000},"source":"Crossref","is-referenced-by-count":0,"title":["Short-Term Outcomes of Coronary Endarterectomy as an Adjunct to Coronary Artery Bypass Grafting: A Systematic Review and Meta-Analysis of Over 100\u2009000 Patients"],"prefix":"10.1093","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-1073-5825","authenticated-orcid":false,"given":"Joshua J","family":"Hon","sequence":"first","affiliation":[{"name":"Department of Surgery and Cancer, Imperial College London , London, W12 0NN,","place":["United Kingdom"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arian","family":"Arjomandi Rad","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, Oxford University Hospitals NHS Foundation Trust , Oxford, OX3 9DU,","place":["United Kingdom"]},{"name":"Department of Cardiothoracic Surgery, Maastricht University Medical Center+ , Maastricht, 6229 HX,","place":["The Netherlands"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Archie","family":"Egrilmezer","sequence":"additional","affiliation":[{"name":"Department of Surgery and Cancer, Imperial College London , London, W12 0NN,","place":["United Kingdom"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fadi Ibrahim","family":"Al-Zubaidi","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, Oxford University Hospitals NHS Foundation Trust , Oxford, OX3 9DU,","place":["United 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Cardiothoracic Surgery, University General Hospital of Larissa , Larissa, 41110,","place":["Greece"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sadeq","family":"Ali-Hasan-Al-Saegh","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School , Hannover, 30625,","place":["Germany"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexander","family":"Weymann","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School , Hannover, 30625,","place":["Germany"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arjang","family":"Ruhparwar","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School , Hannover, 30625,","place":["Germany"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peyman","family":"Sardari Nia","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, Maastricht University Medical Center+ , Maastricht, 6229 HX,","place":["The Netherlands"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2525-5515","authenticated-orcid":false,"given":"Thanos","family":"Athanasiou","sequence":"additional","affiliation":[{"name":"Department of Surgery and Cancer, Imperial College London , London, W12 0NN,","place":["United Kingdom"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonios","family":"Kourliouros","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, Oxford University Hospitals NHS Foundation Trust , Oxford, OX3 9DU,","place":["United 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