{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T14:05:38Z","timestamp":1784729138022,"version":"3.55.0"},"reference-count":18,"publisher":"Oxford University Press (OUP)","issue":"7","license":[{"start":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T00:00:00Z","timestamp":1782950400000},"content-version":"vor","delay-in-days":1,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,7,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>Minimally invasive mitral valve surgery (MIV-MVS) continues to evolve through refinements in surgical technique and perioperative management. This study evaluated the association between arterial cannulation strategy and perioperative adverse events.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Three arterial cannulations were used: central ascending aortic cannulation (AC), open femoral cannulation via groin cutdown (oFC), and percutaneous femoral cannulation (pFC) using pre-closure devices. Patients from 2 centres were assessed for the composite safety end-point of 30-day mortality or stroke, the composite efficacy end-point of all-cause death, stroke, or cannulation-related adverse events, and postoperative delirium. Cannulation-related adverse events included conversion to sternotomy or re-thoracotomy, vessel dissection or bleeding, and cannulation-site infection.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Between January 2013 and January 2020, 823 patients underwent MIV-MVS. Aortic cannulation was performed in 266 patients (32.3%), oFC in 396 (48.1%), and pFC in 161 (19.6%). The composite end-point of 30-day all-cause death or stroke occurred in 19 patients (2.3%) and was similar between AC and FC (odds ratio [OR] 1.16, 95% CI, 0.41-3.16). The extended composite efficacy end-point occurred less frequently with AC than with any FC (OR 0.46, 95% CI, 0.21-0.94), mainly due to fewer access-site complications. Aortic cannulation was also associated with lower odds of perioperative delirium (OR 0.51, 95% CI, 0.29-0.86). No significant difference was observed between oFC and pFC.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>In patients undergoing MIV-MVS, 30-day death or stroke was similar across cannulation strategies. Aortic cannulation was associated with a lower rate of cannulation-related complications and less perioperative delirium than FC, largely reflecting fewer access-site complications. Further prospective external validation is warranted.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/icvts\/ivag185","type":"journal-article","created":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T20:52:06Z","timestamp":1782852726000},"source":"Crossref","is-referenced-by-count":0,"title":["Comparison of Cannulation Strategies for Minimally Invasive Mitral Valve Surgery"],"prefix":"10.1093","volume":"41","author":[{"given":"Juri","family":"Sromicki","sequence":"first","affiliation":[{"name":"Department of Cardiac Surgery, University Hospital Zurich , CH-8091 Z\u00fcrich,","place":["Switzerland"]},{"name":"Department of Cardiac Surgery, Municipal Hospital Triemli , CH-8063 Z\u00fcrich,","place":["Switzerland"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nestoras","family":"Papadopoulos","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery, University Hospital Zurich , CH-8091 Z\u00fcrich,","place":["Switzerland"]},{"name":"Department of Cardiac Surgery, Municipal Hospital Triemli , CH-8063 Z\u00fcrich,","place":["Switzerland"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisa","family":"Tr\u00f6binger","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery, University Hospital Zurich , CH-8091 Z\u00fcrich,","place":["Switzerland"]},{"name":"Department of Cardiac Surgery, Municipal Hospital Triemli , CH-8063 Z\u00fcrich,","place":["Switzerland"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8573-1018","authenticated-orcid":false,"given":"Vasileios","family":"Ntinopoulos","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery, University Hospital Zurich , CH-8091 Z\u00fcrich,","place":["Switzerland"]},{"name":"Department of Cardiac Surgery, Municipal Hospital Triemli , CH-8063 Z\u00fcrich,","place":["Switzerland"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monika","family":"Hebeisen","sequence":"additional","affiliation":[{"name":"Department of Biostatistics, Epidemiology, Biostatistics and Prevention Institute, University of Zurich , CH-8001 Z\u00fcrich,","place":["Switzerland"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0984-9011","authenticated-orcid":false,"given":"Milan","family":"Milojevic","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery, University Hospital Zurich , CH-8091 Z\u00fcrich,","place":["Switzerland"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hector Rodriguez Cetina","family":"Biefer","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery, University Hospital Zurich , CH-8091 Z\u00fcrich,","place":["Switzerland"]},{"name":"Department of Cardiac Surgery, Municipal Hospital Triemli , CH-8063 Z\u00fcrich,","place":["Switzerland"]},{"name":"Center for Experimental and Translational Cardiology (CTEC), University of Z\u00fcrich , CH-8952 Schlieren,","place":["Switzerland"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7910-5152","authenticated-orcid":false,"given":"Omer","family":"Dzemali","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery, University Hospital Zurich , CH-8091 Z\u00fcrich,","place":["Switzerland"]},{"name":"Department of Cardiac Surgery, Municipal Hospital Triemli , CH-8063 Z\u00fcrich,","place":["Switzerland"]},{"name":"Center for Experimental and Translational Cardiology (CTEC), University of Z\u00fcrich , CH-8952 Schlieren,","place":["Switzerland"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2026,7,1]]},"reference":[{"key":"2026072209415269000_ivag185-B1","doi-asserted-by":"publisher","first-page":"ezaf276","DOI":"10.1093\/ejcts\/ezaf276","article-title":"2025 ESC\/EACTS guidelines for the management of valvular heart disease","volume":"67","author":"Praz","year":"2025","journal-title":"Eur J Cardiothorac Surg"},{"key":"2026072209415269000_ivag185-B2","doi-asserted-by":"publisher","first-page":"410","DOI":"10.1161\/CIRCULATIONAHA.116.023340","article-title":"Twenty-year outcome after mitral repair versus replacement for severe degenerative mitral regurgitation: analysis of a large, prospective, multicenter, international registry","volume":"135","author":"Lazam","year":"2017","journal-title":"Circulation"},{"key":"2026072209415269000_ivag185-B3","doi-asserted-by":"publisher","first-page":"1989","DOI":"10.1016\/j.jtcvs.2014.01.046","article-title":"Mitral valve surgery: right lateral minithoracotomy or sternotomy? 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