{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T23:22:39Z","timestamp":1787008959343,"version":"build-2736575974"},"reference-count":25,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2020,1,6]],"date-time":"2020-01-06T00:00:00Z","timestamp":1578268800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,4,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title\/>\n                    <jats:p\/>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>OBJECTIVES<\/jats:title>\n                    <jats:p>This study sought to determine the percentage of patients potentially eligible for implantation of the Sentinel\u2122 Cerebral Protection System (Sentinel-CPS) during transcatheter aortic valve implantation (TAVI) and to identify the reasons for treatment exclusion.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS<\/jats:title>\n                    <jats:p>We retrospectively performed an analysis of pre-TAVI multislice computed tomography (MSCT) aortograms and data review of all patients undergoing a TAVI procedure in 2017 (n\u2009=\u2009317). MSCT evaluation included the assessment of aortic arch anatomy and the vascular dimensions of the brachiocephalic and left common carotid artery. Data analysis focused on comorbid conditions, precluding 6-Fr sheath radial access and filter deployment due to history of previous artery interventions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS<\/jats:title>\n                    <jats:p>MSCT and data analysis showed Sentinel-CPS compatibility in 61.5% of patients (n\u2009=\u2009195). Sentinel-CPS would have been contraindicated in 38.5% (n\u2009=\u2009122) due to one or more of the following: (i) measured diameters of the filter-landing zones &amp;lt;9 or &amp;gt;15\u2009mm in the brachiocephalic artery and &amp;lt;6.5 or &amp;gt;10\u2009mm in the left common carotid artery (n\u2009=\u2009116; 88 with carotid dimensions too small); (ii) significant subclavian artery stenosis (n\u2009=\u20094) or an aberrant subclavian artery (n\u2009=\u20093) precluding Sentinel-CPS implantation and (iii) clinical characteristics including hypersensitivity to nickel\u2013titanium (n\u2009=\u20091), radial artery occlusion (n\u2009=\u20091) or previous left common carotid artery interventions (n\u2009=\u20095).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSIONS<\/jats:title>\n                    <jats:p>MSCT and clinical data supported Sentinel-CPS compatibility in 61.5% of patients. The most common reason for treatment exclusion was inappropriate diameter within the target landing zone of the left carotid artery. Future device development should address this limitation.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/icvts\/ivz306","type":"journal-article","created":{"date-parts":[[2019,12,5]],"date-time":"2019-12-05T07:10:38Z","timestamp":1575529838000},"page":"605-612","source":"Crossref","is-referenced-by-count":12,"title":["Patient eligibility for application of a two-filter cerebral embolic protection device during transcatheter aortic valve implantation: does one size fit all?"],"prefix":"10.1093","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8685-532X","authenticated-orcid":false,"given":"Stephanie","family":"Voss","sequence":"first","affiliation":[{"name":"Department of Cardiovascular Surgery, German Heart Centre Munich, Technische Universit\u00e4t M\u00fcnchen, Munich, Germany"},{"name":"Department of Cardiovascular Surgery, German Heart Centre Munich, Insure (Institute of Translational Cardiac Surgery), Technische Universit\u00e4t M\u00fcnchen, Munich, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johanna","family":"Schechtl","sequence":"first","affiliation":[{"name":"Department of Cardiovascular Surgery, German Heart Centre Munich, Technische Universit\u00e4t M\u00fcnchen, Munich, Germany"},{"name":"Department of Cardiovascular Surgery, German Heart Centre Munich, Insure (Institute of Translational Cardiac Surgery), Technische Universit\u00e4t M\u00fcnchen, Munich, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"N\u00f6bauer","sequence":"first","affiliation":[{"name":"Department of Cardiovascular Surgery, German Heart Centre Munich, Technische Universit\u00e4t M\u00fcnchen, Munich, Germany"},{"name":"Department of Cardiovascular Surgery, German Heart Centre Munich, Insure (Institute of Translational Cardiac Surgery), Technische Universit\u00e4t M\u00fcnchen, Munich, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sabine","family":"Bleiziffer","sequence":"first","affiliation":[{"name":"Clinic for Thoracic and Cardiovascular Surgery, Heart and Diabetes Centre North Rhine Westphalia, Bad Oeynhausen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R\u00fcdiger","family":"Lange","sequence":"first","affiliation":[{"name":"Department of Cardiovascular Surgery, German Heart Centre Munich, Technische Universit\u00e4t M\u00fcnchen, Munich, Germany"},{"name":"Department of Cardiovascular Surgery, German Heart Centre Munich, Insure (Institute of Translational Cardiac Surgery), Technische Universit\u00e4t M\u00fcnchen, Munich, Germany"},{"name":"DZHK (German Centre for Cardiovascular Research), Partner Site Munich Heart Alliance, Munich, 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