{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T05:44:48Z","timestamp":1791179088124,"version":"4.1.0"},"reference-count":31,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2023,4,4]],"date-time":"2023-04-04T00:00:00Z","timestamp":1680566400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"name":"Dagmar Marshall Foundation","award":["500020"],"award-info":[{"award-number":["500020"]}]},{"name":"Else and Mogens Wedell Wedellsborg Foundation","award":["12-20-1"],"award-info":[{"award-number":["12-20-1"]}]},{"DOI":"10.13039\/501100002739","name":"Aarhus University Research Foundation","doi-asserted-by":"publisher","award":["26101"],"award-info":[{"award-number":["26101"]}],"id":[{"id":"10.13039\/501100002739","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Reinholdt W. Jorck and Wife Foundation","award":["19-JU-0367"],"award-info":[{"award-number":["19-JU-0367"]}]},{"DOI":"10.13039\/501100004954","name":"Augustinus Foundation","doi-asserted-by":"publisher","award":["19\u20133361"],"award-info":[{"award-number":["19\u20133361"]}],"id":[{"id":"10.13039\/501100004954","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005747","name":"A.P. M\u00f8ller Foundation","doi-asserted-by":"publisher","award":["19-L-0064"],"award-info":[{"award-number":["19-L-0064"]}],"id":[{"id":"10.13039\/501100005747","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,8,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Few studies have assessed life expectancy of patients with tuberculosis (TB) against a comparable background population, particularly in low-income, high-incidence settings. This study aimed to estimate the life expectancy (LE) of patients with TB in the West African country of Guinea-Bissau and compare it with the LE of the background population.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>This study used data from the Bandim TB cohort from 2004\u201320 as well as census data from the capital of Guinea-Bissau. LE was estimated using a bootstrapped Kaplan-Meier survival analysis for patients with TB and the background population, stratifying by age of entry and various patient subgroups. The analysis was further stratified by diagnosis period and length of schooling (an indicator of socioeconomic status), to assess their influence on LE. A sensitivity analysis was performed assuming death at loss to follow-up.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>The analysis included 2278 patients and a background population of 169\u200a760 individuals. Overall median LE among 30-year-old patients with TB was 10.7\u2009years (95% CI: 8.7\u201312.6), compared with 35.8 (95% CI: 35.1\u201336.5) in the background population. LE was shorter in HIV-infected patients and those who had unsuccessful treatment outcome; however, even among those who were both uninfected with HIV and experienced successful treatment outcome, LE was 20% shorter than in the background population. Longer schooling appeared to decrease mortality.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>TB substantially shortens LE. This effect is present even in patients who are uninfected with HIV and who have successful treatment outcome.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ije\/dyad039","type":"journal-article","created":{"date-parts":[[2023,4,4]],"date-time":"2023-04-04T21:05:27Z","timestamp":1680642327000},"page":"1112-1123","source":"Crossref","is-referenced-by-count":5,"title":["Life expectancy among patients with pulmonary tuberculosis is less than one-third of life expectancy in the background population in Guinea-Bissau\u2014an observational study"],"prefix":"10.1093","volume":"52","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2302-0461","authenticated-orcid":false,"given":"Anders Solitander","family":"Bohlbro","sequence":"first","affiliation":[{"name":"Bandim Health Project, INDEPTH Network, Apartado 861 , Bissau, Guinea-Bissau"},{"name":"Department of Infectious Diseases, Aarhus University Hospital , Aarhus, Denmark"},{"name":"Center for Global Health, Department of Public Health, Aarhus University , Aarhus, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bo Langhoff","family":"H\u00f8nge","sequence":"additional","affiliation":[{"name":"Bandim Health Project, INDEPTH Network, Apartado 861 , Bissau, Guinea-Bissau"},{"name":"Department of Infectious Diseases, Aarhus University Hospital , Aarhus, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Engell-S\u00f8rensen","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases, Aarhus University Hospital , Aarhus, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio Matteus","family":"Mendes","sequence":"additional","affiliation":[{"name":"Bandim Health Project, INDEPTH Network, Apartado 861 , Bissau, Guinea-Bissau"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Armando","family":"Sifna","sequence":"additional","affiliation":[{"name":"Bandim Health Project, INDEPTH Network, Apartado 861 , Bissau, Guinea-Bissau"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Victor","family":"Gomes","sequence":"additional","affiliation":[{"name":"Bandim Health Project, INDEPTH Network, Apartado 861 , Bissau, Guinea-Bissau"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frauke","family":"Rudolf","sequence":"additional","affiliation":[{"name":"Bandim Health Project, INDEPTH Network, Apartado 861 , Bissau, Guinea-Bissau"},{"name":"Department of Infectious Diseases, Aarhus University Hospital , Aarhus, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Wejse","sequence":"additional","affiliation":[{"name":"Bandim Health Project, INDEPTH Network, Apartado 861 , Bissau, Guinea-Bissau"},{"name":"Department of Infectious Diseases, Aarhus University Hospital , Aarhus, Denmark"},{"name":"Center for Global Health, Department of Public Health, Aarhus University , Aarhus, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2023,4,4]]},"reference":[{"key":"2023080222385179200_dyad039-B1","volume-title":"Global Tuberculosis Report 2020","author":"World Health Organization","year":"2020"},{"key":"2023080222385179200_dyad039-B2","doi-asserted-by":"crossref","first-page":"1329","DOI":"10.1016\/S1473-3099(18)30625-X","article-title":"Global, regional, and national burden of tuberculosis, 1990\u20132016: results from the Global Burden of Diseases, Injuries, and Risk Factors 2016 Study","volume":"18","author":"Kyu","year":"2018","journal-title":"Lancet Infect Dis"},{"key":"2023080222385179200_dyad039-B3","doi-asserted-by":"crossref","first-page":"e1372","DOI":"10.1016\/S2214-109X(21)00299-0","article-title":"Economic impact of tuberculosis mortality in 120 countries and the cost of not achieving the Sustainable Development Goals tuberculosis targets: a full-income 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