{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,19]],"date-time":"2026-07-19T03:41:11Z","timestamp":1784432471932,"version":"3.55.0"},"reference-count":52,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T00:00:00Z","timestamp":1762473600000},"content-version":"vor","delay-in-days":24,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"National Institutes of Health and the National Cancer Institute","award":["U01 CA164974"],"award-info":[{"award-number":["U01 CA164974"]}]},{"name":"National Institutes of Health and the National Cancer Institute","award":["R01 CA249982"],"award-info":[{"award-number":["R01 CA249982"]}]},{"name":"Karin Grunebaum Cancer Research Foundation"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,10,14]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Black Americans have a &amp;gt;2-fold increased risk of multiple myeloma (MM) compared with other racial\/ethnic groups. The underlying biological and environmental mechanisms contributing to this disparity remain poorly understood. Emerging evidence suggests that social and economic factors associated with neighborhoods may influence risk.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We evaluated associations between two neighborhood-level indices by measuring deprivation and socioeconomic status and MM within the Black Women\u2019s Health Study\u2014a prospective cohort of 59\u2009000 Black women established in 1995. Participant addresses at baseline and over follow-up were geocoded and linked with United States Census Bureau data. We used Cox proportional hazards regression to calculate hazard ratios (HRs) and 95% confidence intervals (CIs) for the association of neighborhood indices, categorized into quartiles, and MM incidence. Multivariable models were adjusted for age, body mass index, educational attainment, alcohol consumption, physical activity, cigarette smoking, and geographic region.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>During follow-up through 2021, we identified 276 incident MM cases. In time-varying age-adjusted models, women living in areas of high disadvantage (vs lowest) and low socioeconomic status (vs highest) had a higher incidence of MM than women living in areas of privilege (multivariable HR: 1.48, 95% CI: 1.02, 2.13; HR: 1.28, 95% CI: 0.87, 1.90, respectively).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Black women living in neighborhoods of high concentrated disadvantage or low socioeconomic status have an increased MM risk. Future studies to identify specific neighborhood-level factors that might influence the risk of MM would be beneficial. Ultimately, community reinvestment may offer an opportunity to reduce the increasing burden of MM among Black women.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/ije\/dyaf188","type":"journal-article","created":{"date-parts":[[2025,11,9]],"date-time":"2025-11-09T08:50:30Z","timestamp":1762678230000},"source":"Crossref","is-referenced-by-count":1,"title":["Neighborhood disadvantage and multiple myeloma incidence in the Black Women\u2019s Health Study"],"prefix":"10.1093","volume":"54","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0877-9058","authenticated-orcid":false,"given":"Etienne X","family":"Holder","sequence":"first","affiliation":[{"name":"Slone Epidemiology Center at Boston University , Boston, MA,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raphael","family":"Szalat","sequence":"additional","affiliation":[{"name":"Boston University Chobanian & Avedisian School of Medicine , Boston, MA,","place":["United 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