{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,20]],"date-time":"2026-06-20T17:32:45Z","timestamp":1781976765668,"version":"3.54.5"},"reference-count":32,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T00:00:00Z","timestamp":1771459200000},"content-version":"vor","delay-in-days":1,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"China Scholarship Council and the European Union programme EU4Health","award":["101101252"],"award-info":[{"award-number":["101101252"]}]},{"name":"National Institutes of Health\/National Cancer Institute","award":["U01CA265729"],"award-info":[{"award-number":["U01CA265729"]}]},{"name":"European Union programme EU4Health","award":["101101252"],"award-info":[{"award-number":["101101252"]}]},{"name":"National Institutes of Health\/National Cancer Institute","award":["K08CA252635"],"award-info":[{"award-number":["K08CA252635"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,2,18]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Evidence of gastric cancer (GC) screening\u2019s impact on GC incidence remains limited. In 2002, South Korea started a nationwide GC screening program. This study uses a quasi-experimental design to evaluate the effect of the program on GC incidence in Seoul.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Using a flexible synthetic control method (SCM), we estimated the impact of GC screening on age-standardized GC incidence in Seoul. Annual age-specific GC incidence data were obtained from the Seoul Cancer Registry and Cancer Incidence in Five Continents Plus database. Post-intervention trends in GC incidence between Seoul and the synthetic control were compared to estimate average rate ratios (RRs) with 95% confidence intervals (CIs). Several sensitivity and alternative analyses were performed, including a modified age-period-cohort (APC) analysis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The screening program was associated with a higher GC incidence in Seoul compared to the synthetic control, with an average post-intervention RR of 1.11 (95% CI: 0.99\u20131.24). After 2002, the start of the screening program, there was a noticeable increase in the post-intervention differences between Seoul and the synthetic control, which peaked in 2011 (RR 1.26), and then began to fall. The results were robust across sensitivity analyses and alternative analyses. The modified APC analysis indicated that after initially expanding and then diminishing, the effect eventually reversed, resulting in a reduction in incidence.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>These findings suggest that healthcare sectors should anticipate an immediate increase in care demands following GC screening implementation. While a subsequent reduction in GC incidence is expected, the potential preventive impact remains inconclusive.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/ije\/dyag018","type":"journal-article","created":{"date-parts":[[2026,1,29]],"date-time":"2026-01-29T12:45:15Z","timestamp":1769690715000},"source":"Crossref","is-referenced-by-count":1,"title":["The impact of an organized screening program on gastric cancer incidence: a quasi-experimental study"],"prefix":"10.1093","volume":"55","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1184-9758","authenticated-orcid":false,"given":"Dianqin","family":"Sun","sequence":"first","affiliation":[{"name":"Department of Public Health, Erasmus MC, University Medical Center Rotterdam , Rotterdam,","place":["The Netherlands"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Duco T","family":"M\u00fclder","sequence":"additional","affiliation":[{"name":"Department of Public Health, Erasmus MC, University Medical Center Rotterdam , Rotterdam,","place":["The Netherlands"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyu-Won","family":"Jung","sequence":"additional","affiliation":[{"name":"National Cancer Control Institute, National Cancer Center , Goyang,","place":["Korea"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jin Young","family":"Park","sequence":"additional","affiliation":[{"name":"Early Detection, Prevention, and Infections Branch, International Agency for Research on Cancer , Lyon,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mina","family":"Suh","sequence":"additional","affiliation":[{"name":"National Cancer Control Institute, National Cancer Center , Goyang,","place":["Korea"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yige","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Biostatistics and CAUSALab, Harvard T.H. Chan School of Public Health, Harvard University , Boston, MA,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4403-6537","authenticated-orcid":false,"given":"Daan","family":"Nieboer","sequence":"additional","affiliation":[{"name":"Department of Public Health, Erasmus MC, University Medical Center Rotterdam , Rotterdam,","place":["The Netherlands"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2585-8479","authenticated-orcid":false,"given":"Chisato","family":"Hamashima","sequence":"additional","affiliation":[{"name":"Division of Health Policy, Department of Nursing, Faculty of Medical Technology, Teikyo University , Tokyo,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weiran","family":"Han","sequence":"additional","affiliation":[{"name":"Department of Public Health, Erasmus MC, University Medical Center Rotterdam , Rotterdam,","place":["The Netherlands"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9103-9757","authenticated-orcid":false,"given":"Manon C W","family":"Spaander","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology, Erasmus MC, University Medical Center Rotterdam , Rotterdam,","place":["the Netherlands"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9328-4545","authenticated-orcid":false,"given":"Uri","family":"Ladabaum","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology, Department of Medicine, Stanford University School of Medicine , Stanford, CA,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert J","family":"Huang","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology, Department of Medicine, Stanford University School 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