{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T21:06:45Z","timestamp":1789247205338,"version":"build-2803163510"},"reference-count":28,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2026,6,24]],"date-time":"2026-06-24T00:00:00Z","timestamp":1782259200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"Royal College of Physicians Eden Fellowship in Paediatrics 2002"},{"DOI":"10.13039\/100010269","name":"Wellcome Trust","doi-asserted-by":"publisher","award":["083707"],"award-info":[{"award-number":["083707"]}],"id":[{"id":"10.13039\/100010269","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Wellcome Trust Strategic Award","award":["084774"],"award-info":[{"award-number":["084774"]}]},{"name":"European Commission Strategic Award","award":["FP-7"],"award-info":[{"award-number":["FP-7"]}]},{"DOI":"10.13039\/501100000265","name":"Medical Research Council UK","doi-asserted-by":"crossref","award":["MR\/T038292\/1"],"award-info":[{"award-number":["MR\/T038292\/1"]}],"id":[{"id":"10.13039\/501100000265","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100000265","name":"Medical Research Council UK","doi-asserted-by":"crossref","award":["MR\/V001221\/1"],"award-info":[{"award-number":["MR\/V001221\/1"]}],"id":[{"id":"10.13039\/501100000265","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Australian Government Research Training Program (RTP) Scholarship"},{"name":"University of Bristol and UK Medical Research Council","award":["MC_UU_00032\/5"],"award-info":[{"award-number":["MC_UU_00032\/5"]}]},{"name":"European Union\u2019s Horizon Europe Research and Innovation Programme","award":["874739"],"award-info":[{"award-number":["874739"]}]},{"name":"LongITools","award":["101137146"],"award-info":[{"award-number":["101137146"]}]},{"DOI":"10.13039\/100014013","name":"UKRI","doi-asserted-by":"publisher","award":["10099041"],"award-info":[{"award-number":["10099041"]}],"id":[{"id":"10.13039\/100014013","id-type":"DOI","asserted-by":"publisher"}]},{"name":"National Institution of Nutrition, Indian Council of Medical Research"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,6,24]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Cardiovascular disease (CVD) is the leading cause of disability-adjusted life years in South Asia, with adverse trends in CVD risk seen in rural residents in recent decades. Assessment of life-course trajectories of CVD risk factors is important to understand CVD aetiology.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>The Andhra Pradesh Children and Parents cohort Study included all children (n\u2009=\u20092601) born during 1987\u201390 and their mothers (n\u2009=\u20091963) residing in 29 villages of South India. Participants were followed up in 2003\u201305, 2009\u201310, 2010\u201312, and 2021\u201323. Children (n\u2009=\u20094777 observations, 35% female) were assessed for body mass index (BMI), waist circumference, waist\u2013hip ratio, waist\u2013height ratio, fasting glucose, and central and peripheral skinfolds. For mothers (n\u2009=\u20093830 observations), repeated measures of BMI were available. Linear mixed-effect models with a random slope were used to model trajectories of CVD risk factors.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>BMI increased with age and the predicted mean BMI reached the World Health Organization\u2019s increased risk action point for adult South Asians (\u226523\u2009kg\/m2) at 28\u2009years for male and 31\u2009years for female children, while, for mothers, it was much later at 43\u201365\u2009years. In male children compared with females, there was a faster progression to prediabetes, higher abdominal fat deposition, and a higher rate of increase in subscapular skinfolds.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>South Asians living in rural areas showed increasing trajectories of several CVD risk factors, particularly in males. This highlights the need for interventions to mitigate the potential CVD burden.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/ije\/dyag080","type":"journal-article","created":{"date-parts":[[2026,5,3]],"date-time":"2026-05-03T20:58:56Z","timestamp":1777841936000},"source":"Crossref","is-referenced-by-count":0,"title":["Life-course trajectories of cardiovascular disease risk factors in rural India: Andhra Pradesh Children and Parents Study (APCAPS) 2003\u20132023"],"prefix":"10.1093","volume":"55","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8942-9692","authenticated-orcid":false,"given":"Chitra","family":"Sharma","sequence":"first","affiliation":[{"name":"School of Health Sciences, College of Health and Medicine, University of Tasmania, The Shed , Launceston, TAS 7250,","place":["Australia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2763-4647","authenticated-orcid":false,"given":"Ana","family":"Goncalves 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